IN2012DN06061A - - Google Patents

Download PDF

Info

Publication number
IN2012DN06061A
IN2012DN06061A IN6061DEN2012A IN2012DN06061A IN 2012DN06061 A IN2012DN06061 A IN 2012DN06061A IN 6061DEN2012 A IN6061DEN2012 A IN 6061DEN2012A IN 2012DN06061 A IN2012DN06061 A IN 2012DN06061A
Authority
IN
India
Prior art keywords
pyrazol
thiazole
disorders
inhibitors
diseases
Prior art date
Application number
Other languages
English (en)
Inventor
Nicole Cathleen Goodwin
David Brent Rawlins
Original Assignee
Lexicon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexicon Pharmaceuticals Inc filed Critical Lexicon Pharmaceuticals Inc
Publication of IN2012DN06061A publication Critical patent/IN2012DN06061A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
IN6061DEN2012 2010-01-22 2011-01-21 IN2012DN06061A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29739710P 2010-01-22 2010-01-22
PCT/US2011/021970 WO2011091204A1 (en) 2010-01-22 2011-01-21 5-(1h-pyrazol-5-yl)thiazole-based compounds for the treatment of diseases and disorders of the eye

Publications (1)

Publication Number Publication Date
IN2012DN06061A true IN2012DN06061A (ja) 2015-09-18

Family

ID=43760212

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6061DEN2012 IN2012DN06061A (ja) 2010-01-22 2011-01-21

Country Status (8)

Country Link
US (1) US20130059896A1 (ja)
EP (1) EP2525794A1 (ja)
JP (1) JP2013518048A (ja)
CN (1) CN102711758A (ja)
AU (1) AU2011207280A1 (ja)
CA (1) CA2786730A1 (ja)
IN (1) IN2012DN06061A (ja)
WO (1) WO2011091204A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012170931A2 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
US20130143927A1 (en) * 2011-06-10 2013-06-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2013059677A1 (en) 2011-10-19 2013-04-25 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2018055097A1 (en) 2016-09-23 2018-03-29 Cellipse Lim kinase inhibitors, pharmaceutical composition and method of use in limk-mediated diseases
CN115197166B (zh) * 2022-07-11 2024-07-02 安徽英瑞骐生物科技有限公司 一种4-甲基-2-肼基苯并噻唑的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
AU8998598A (en) * 1997-09-11 1999-03-29 Nissan Chemical Industries Ltd. Pyrazole compounds and plant disease control agent
WO2002099140A1 (en) 2001-06-05 2002-12-12 Exelixis, Inc. GLRAs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
CA2452202A1 (en) 2001-06-27 2003-01-09 The Walter And Eliza Hall Institute Of Medical Research Diagnostic methods and agents
WO2004047868A1 (ja) * 2002-11-27 2004-06-10 Santen Pharmaceutical Co., Ltd. Limキナーゼ阻害作用を有する化合物を有効成分とする緑内障治療剤
TWI336257B (en) 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
EP2532240A3 (en) 2007-04-03 2013-03-13 E. I. du Pont de Nemours and Company Substituted benzene fungicides
EP2188289B1 (en) 2007-08-08 2015-10-28 Lexicon Pharmaceuticals, Inc. (7h-pyrrolo[2,3-d]pyrimidin-4-yl)-piperazines as kinase inhibitors for the treatment of cancer and inflammation
US8193202B2 (en) 2008-04-21 2012-06-05 Lexicon Pharmaceuticals, Inc. LIMK2 inhibitors, compositions comprising them, and methods of their use

Also Published As

Publication number Publication date
EP2525794A1 (en) 2012-11-28
JP2013518048A (ja) 2013-05-20
CN102711758A (zh) 2012-10-03
AU2011207280A1 (en) 2012-07-19
WO2011091204A1 (en) 2011-07-28
CA2786730A1 (en) 2011-07-28
US20130059896A1 (en) 2013-03-07

Similar Documents

Publication Publication Date Title
WO2014028600A3 (en) 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
TN2013000348A1 (en) Compounds and compositions as trk inhibitors
PH12014501947A1 (en) Serine/threonine kinase inhibitors
WO2014028591A3 (en) N-ALKYLATED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
MX2015012431A (es) Pirrol amida como inhibidores.
WO2014031928A3 (en) Heterocyclic modulators of hif activity for treatment of disease
WO2014179564A8 (en) Thiazolopyrrolidine inhibitors of ror-gamma
MX2014012695A (es) Derivados de isoindolona.
MX2013011908A (es) Composiciones y usos terapeuticos de inhibidores de cinasa epsilon relacionados con cinasa i-kappa b (ikk) y cinasa 1 de union tank.
EA023222B8 (ru) Пиразолилхиноксалиновые ингибиторы киназы
AU2012214029A8 (en) Rorgammat inhibitors
MX353806B (es) Quinolinas como moduladores de cinasas del receptor del factor de crecimiento de fibroblasto (fgfr).
EA024842B9 (ru) Соединения в качестве модуляторов протеинкиназы pi3k
MX2016008449A (es) Inhibidores de serina/treonina cinasa.
AU2012258977A8 (en) Inhibitors of LRRK2 kinase activity
WO2012013282A8 (en) Bicyclic azaheterocyclic carboxamides as inhibitors of the kinase p70s6k
WO2014031933A3 (en) Heterocyclic modulators of hif activity for treatment of disease
IN2015DN01151A (ja)
MY167898A (en) Co-crystals and salts of ccr3-inhibitors
WO2012048129A3 (en) Inhibitors of polo-like kinase
WO2014031936A3 (en) Heterocyclic modulators of hif activity for treatment of disease
MX337849B (es) Composiciones y metodos para inhibicion de la via jak.
MX345127B (es) Derivados de tiazol.
WO2011150201A3 (en) Azolyl amide compounds and methods of use thereof
EA032271B9 (ru) Вещества, фармацевтическая композиция и методы применения при лечении воспалительных заболеваний