IN2012DN02589A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN02589A IN2012DN02589A IN2589DEN2012A IN2012DN02589A IN 2012DN02589 A IN2012DN02589 A IN 2012DN02589A IN 2589DEN2012 A IN2589DEN2012 A IN 2589DEN2012A IN 2012DN02589 A IN2012DN02589 A IN 2012DN02589A
- Authority
- IN
- India
- Prior art keywords
- binding
- hla
- peptide
- mhc
- binding peptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23714709P | 2009-08-26 | 2009-08-26 | |
US33561110P | 2010-01-06 | 2010-01-06 | |
PCT/US2010/002330 WO2011031298A1 (en) | 2009-08-26 | 2010-08-24 | Compositions that induce t cell help |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN02589A true IN2012DN02589A (sl) | 2015-08-28 |
Family
ID=43732728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN2589DEN2012 IN2012DN02589A (sl) | 2009-08-26 | 2010-08-24 |
Country Status (15)
Country | Link |
---|---|
US (1) | US20110110965A1 (sl) |
EP (2) | EP2470554B1 (sl) |
JP (2) | JP5933437B2 (sl) |
KR (2) | KR101873179B1 (sl) |
CN (3) | CN107715118A (sl) |
AU (2) | AU2010293059B2 (sl) |
BR (1) | BR112012003977A2 (sl) |
CA (1) | CA2771863A1 (sl) |
EA (2) | EA023897B1 (sl) |
ES (1) | ES2641892T3 (sl) |
IL (2) | IL218254A (sl) |
IN (1) | IN2012DN02589A (sl) |
MX (1) | MX343908B (sl) |
PL (1) | PL2470554T3 (sl) |
WO (1) | WO2011031298A1 (sl) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA028288B1 (ru) | 2009-05-27 | 2017-10-31 | Селекта Байосайенсиз, Инк. | Наноносители, имеющие компоненты с различными скоростями высвобождения |
EA023897B1 (ru) * | 2009-08-26 | 2016-07-29 | Селекта Байосайенсиз, Инк. | Композиции, которые индуцируют хелперное действие т-клеток |
US20110293700A1 (en) | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Nanocarrier compositions with uncoupled adjuvant |
WO2012061717A1 (en) | 2010-11-05 | 2012-05-10 | Selecta Biosciences, Inc. | Modified nicotinic compounds and related methods |
AU2011329850B2 (en) * | 2010-11-16 | 2017-03-02 | Selecta Biosciences, Inc. | Immunostimulatory oligonucleotides |
WO2012149405A2 (en) | 2011-04-29 | 2012-11-01 | Selecta Biosciences, Inc. | Tolerogenic synthetic nanocarriers for regulating innate immune responses |
KR20120132183A (ko) | 2011-05-27 | 2012-12-05 | 포항공과대학교 산학협력단 | 종양 조직에서 유래한 나노소포체 및 이를 이용한 암 백신 |
EP2736537A4 (en) | 2011-07-29 | 2015-04-15 | Selecta Biosciences Inc | SYNTHETIC NANOTRANSPORTERS FOR THE PRODUCTION OF HUMOROUS AND CYTOTOXIC T-LYMPHOCY (CTL) IMMUNE REACTIONS |
EP2791160B1 (en) | 2011-12-16 | 2022-03-02 | ModernaTX, Inc. | Modified mrna compositions |
US10258698B2 (en) | 2013-03-14 | 2019-04-16 | Modernatx, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
ES2842206T3 (es) | 2013-05-03 | 2021-07-13 | Selecta Biosciences Inc | Métodos y composiciones para potenciar linfocitos T reguladores CD4+ |
PT3134131T (pt) | 2014-04-23 | 2022-03-24 | Modernatx Inc | Vacinas de ácidos nucleicos |
US20170204152A1 (en) | 2014-07-16 | 2017-07-20 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
EA201790533A1 (ru) | 2014-09-07 | 2017-07-31 | Селекта Байосайенсиз, Инк. | Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса, предназначенного для модулирования экспрессии генов |
JP2018508481A (ja) * | 2015-02-02 | 2018-03-29 | ザ ユニバーシティ オブ バーミンガム | 複数のt細胞エピトープを有する標的化部分ペプチドエピトープ複合体 |
AU2018236123B2 (en) | 2017-03-11 | 2024-04-18 | Selecta Biosciences, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
CA3061206A1 (en) * | 2017-04-22 | 2018-10-25 | Immunomic Therapeutics, Inc. | Improved lamp constructs |
KR20240027895A (ko) | 2017-05-02 | 2024-03-04 | 이뮤노믹 쎄라퓨틱스, 인크. | 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물 |
JP7340517B2 (ja) * | 2017-08-31 | 2023-09-07 | シングロン エスエー | バクテリオシン及び抗菌ペプチドを作製するための方法及び組成物 |
WO2019061297A1 (zh) * | 2017-09-29 | 2019-04-04 | 苏州工业园区唯可达生物科技有限公司 | 一种cd4辅助性t细胞表位融合肽及其疫苗 |
TW202003031A (zh) | 2018-04-10 | 2020-01-16 | 瑞士商Ac免疫有限公司 | 抗Aβ治療性疫苗 |
Family Cites Families (125)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4946929A (en) | 1983-03-22 | 1990-08-07 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
US6309669B1 (en) * | 1984-03-16 | 2001-10-30 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix |
US4638045A (en) | 1985-02-19 | 1987-01-20 | Massachusetts Institute Of Technology | Non-peptide polyamino acid bioerodible polymers |
US4806621A (en) | 1986-01-21 | 1989-02-21 | Massachusetts Institute Of Technology | Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article |
US5804178A (en) | 1986-11-20 | 1998-09-08 | Massachusetts Institute Of Technology | Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue |
CA1340581C (en) | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
US5736372A (en) | 1986-11-20 | 1998-04-07 | Massachusetts Institute Of Technology | Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure |
US5912017A (en) * | 1987-05-01 | 1999-06-15 | Massachusetts Institute Of Technology | Multiwall polymeric microspheres |
US5019379A (en) | 1987-07-31 | 1991-05-28 | Massachusetts Institute Of Technology | Unsaturated polyanhydrides |
US6130082A (en) | 1988-05-05 | 2000-10-10 | American Cyanamid Company | Recombinant flagellin vaccines |
US5180806A (en) * | 1988-05-16 | 1993-01-19 | The Scripps Research Institute | Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods |
US5010167A (en) | 1989-03-31 | 1991-04-23 | Massachusetts Institute Of Technology | Poly(amide-and imide-co-anhydride) for biological application |
US5389640A (en) | 1991-03-01 | 1995-02-14 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
GB9113809D0 (en) * | 1991-06-26 | 1991-08-14 | Cancer Res Campaign Tech | Papillomavirus l2 protein |
JP3755890B2 (ja) * | 1992-06-25 | 2006-03-15 | スミスクライン・ビーチャム・バイオロジカルス(ソシエテ・アノニム) | アジュバント含有ワクチン組成物 |
US6337070B1 (en) * | 1993-04-29 | 2002-01-08 | Takara Shuzo Co., Ltd. | Polypeptides for use in generating anti-human influenza virus antibodies |
US5399665A (en) | 1992-11-05 | 1995-03-21 | Massachusetts Institute Of Technology | Biodegradable polymers for cell transplantation |
ES2131676T3 (es) * | 1993-01-11 | 1999-08-01 | Dana Farber Cancer Inst Inc | Induccion de respuestas con linfocitos t citotoxicos. |
US5512600A (en) | 1993-01-15 | 1996-04-30 | Massachusetts Institute Of Technology | Preparation of bonded fiber structures for cell implantation |
US5514378A (en) | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
US5565215A (en) | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
WO1995003035A1 (en) * | 1993-07-23 | 1995-02-02 | Massachusetts Institute Of Technology | Polymerized liposomes with enhanced stability for oral delivery |
US5543158A (en) | 1993-07-23 | 1996-08-06 | Massachusetts Institute Of Technology | Biodegradable injectable nanoparticles |
US6485729B1 (en) * | 1993-09-13 | 2002-11-26 | Protein Sciences Corporation | Neuraminidase-supplemented compositions |
AUPM358894A0 (en) * | 1994-01-31 | 1994-02-24 | Csl Limited | Modified papilloma virus l2 protein and vlps formed therefrom |
US5693325A (en) * | 1994-03-15 | 1997-12-02 | Molecumetics, Ltd. | Peptide vaccines and methods relating thereto |
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6007845A (en) | 1994-07-22 | 1999-12-28 | Massachusetts Institute Of Technology | Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
GB9420146D0 (en) * | 1994-10-06 | 1994-11-23 | Cancer Res Campaign Tech | Papillomavirus vaccine |
US5716404A (en) | 1994-12-16 | 1998-02-10 | Massachusetts Institute Of Technology | Breast tissue engineering |
US6123727A (en) | 1995-05-01 | 2000-09-26 | Massachusetts Institute Of Technology | Tissue engineered tendons and ligaments |
US5866132A (en) * | 1995-06-07 | 1999-02-02 | Alberta Research Council | Immunogenic oligosaccharide compositions |
US6095148A (en) | 1995-11-03 | 2000-08-01 | Children's Medical Center Corporation | Neuronal stimulation using electrically conducting polymers |
US5902599A (en) | 1996-02-20 | 1999-05-11 | Massachusetts Institute Of Technology | Biodegradable polymer networks for use in orthopedic and dental applications |
US6946133B1 (en) * | 1996-03-20 | 2005-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Prostate specific antigen oligo-epitope peptide |
US6599739B1 (en) * | 1996-07-17 | 2003-07-29 | The United States Of America As Represented By The Department Of Health & Human Services | Infectious papillomavirus pseudoviral particles |
CA2262001C (en) * | 1996-08-05 | 2003-05-20 | President And Fellows Of Harvard College | Mhc binding peptide oligomers and methods of use |
US6368598B1 (en) * | 1996-09-16 | 2002-04-09 | Jcrt Radiation Oncology Support Services, Inc. | Drug complex for treatment of metastatic prostate cancer |
KR100518903B1 (ko) | 1996-10-25 | 2005-10-06 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | Th2 매개 질병 및 관련 질병의 치료용 면역 반응 조절 화합물 |
US6211159B1 (en) | 1997-04-11 | 2001-04-03 | University Of Toronto | Flagellin gene, FlaC of campylobacter |
US6060082A (en) * | 1997-04-18 | 2000-05-09 | Massachusetts Institute Of Technology | Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery |
US5837752A (en) | 1997-07-17 | 1998-11-17 | Massachusetts Institute Of Technology | Semi-interpenetrating polymer networks |
ES2323098T3 (es) * | 1997-09-16 | 2009-07-06 | Oregon Health And Science University | Moleculas de mhc recombinantes utiles para la manipulacion de celulas t especificas de antigeno. |
US6329381B1 (en) | 1997-11-28 | 2001-12-11 | Sumitomo Pharmaceuticals Company, Limited | Heterocyclic compounds |
US6254890B1 (en) * | 1997-12-12 | 2001-07-03 | Massachusetts Institute Of Technology | Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids |
US6197229B1 (en) * | 1997-12-12 | 2001-03-06 | Massachusetts Institute Of Technology | Method for high supercoiled DNA content microspheres |
US6686446B2 (en) | 1998-03-19 | 2004-02-03 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
US6506577B1 (en) | 1998-03-19 | 2003-01-14 | The Regents Of The University Of California | Synthesis and crosslinking of catechol containing copolypeptides |
US6632922B1 (en) | 1998-03-19 | 2003-10-14 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
GB9808932D0 (en) * | 1998-04-27 | 1998-06-24 | Chiron Spa | Polyepitope carrier protein |
EP1078092B1 (en) * | 1998-05-13 | 2011-08-03 | Epimmune Inc. | Expression vectors for stimulating an immune response and methods of using the same |
EP1388586A3 (en) * | 1998-05-29 | 2004-05-26 | Epimmune Inc. | Identification of broadly reactive DR restricted epitopes |
WO1999061916A1 (en) * | 1998-05-29 | 1999-12-02 | Epimmune, Inc. | Identification of broadly reactive dr restricted epitopes |
US6306640B1 (en) * | 1998-10-05 | 2001-10-23 | Genzyme Corporation | Melanoma antigenic peptides |
TR200100936T2 (tr) * | 1998-10-05 | 2001-08-21 | Pharmexa A/S | Terapötik aşılama |
AU750587B2 (en) * | 1998-10-16 | 2002-07-25 | Smithkline Beecham Biologicals (Sa) | Adjuvant systems and vaccines |
US6232082B1 (en) * | 1998-12-01 | 2001-05-15 | Nabi | Hapten-carrier conjugates for treating and preventing nicotine addiction |
DE60014076T2 (de) * | 1999-04-19 | 2005-10-13 | Glaxosmithkline Biologicals S.A. | Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid |
MXPA01010750A (es) * | 1999-04-23 | 2003-08-20 | Alza Corp | Conjugado que tiene un enlace dividible para utilizarse en un liposoma. |
US7238368B2 (en) * | 1999-04-23 | 2007-07-03 | Alza Corporation | Releasable linkage and compositions containing same |
US6800296B1 (en) * | 1999-05-19 | 2004-10-05 | Massachusetts Institute Of Technology | Modification of surfaces using biological recognition events |
US7223398B1 (en) | 1999-11-15 | 2007-05-29 | Dynavax Technologies Corporation | Immunomodulatory compositions containing an immunostimulatory sequence linked to antigen and methods of use thereof |
CN1406140A (zh) | 2000-02-28 | 2003-03-26 | 吉倪塞思公司 | 纳米胶囊包封系统与方法 |
US20030129251A1 (en) | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
US20020165176A1 (en) * | 2000-05-01 | 2002-11-07 | Haynes Joel R. | Nucleic acid immunization |
WO2001085208A2 (en) * | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
US7192725B2 (en) | 2000-05-19 | 2007-03-20 | University Of Toronto | Flagellin gene, flaC of Campylobacter |
GB0025414D0 (en) | 2000-10-16 | 2000-11-29 | Consejo Superior Investigacion | Nanoparticles |
US7097837B2 (en) * | 2001-02-19 | 2006-08-29 | Pharmexa A/S | Synthetic vaccine agents |
US20030175950A1 (en) * | 2001-05-29 | 2003-09-18 | Mcswiggen James A. | RNA interference mediated inhibition of HIV gene expression using short interfering RNA |
WO2003020797A1 (en) | 2001-08-30 | 2003-03-13 | The Regents Of The University Of California | Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers |
US20040230380A1 (en) * | 2002-01-04 | 2004-11-18 | Xencor | Novel proteins with altered immunogenicity |
NZ535952A (en) | 2002-04-04 | 2009-01-31 | Coley Pharm Gmbh | Immunostimulatory G,U-containing oligoribonucleotides |
FR2840499B1 (fr) * | 2002-05-30 | 2004-12-10 | Cit Alcatel | Procede et dispositif de controle d'acces a un reseau local de communications sans fil |
AU2003302226A1 (en) * | 2002-09-24 | 2004-06-30 | University Of Kentucky Research Foundation | Nanoparticle-based vaccine delivery system containing adjuvant |
JP5404990B2 (ja) * | 2002-10-23 | 2014-02-05 | グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム | マラリアに対するワクチン接種の方法 |
DE602004008582T2 (de) * | 2003-02-17 | 2008-05-21 | Peter Burkhard | Peptidische nanoteilchen als arzneimittelabgabe- und antigen-display-systeme |
US7727969B2 (en) * | 2003-06-06 | 2010-06-01 | Massachusetts Institute Of Technology | Controlled release nanoparticle having bound oligonucleotide for targeted delivery |
CA2534060C (en) * | 2003-07-30 | 2012-06-12 | Vaccine Research Institute Of San Diego | Hepatitis virus core proteins as vaccine platforms and methods of use thereof |
US20050137156A1 (en) * | 2003-08-09 | 2005-06-23 | Johnston Stephen A. | Methods and compositions for generating an immune response |
US20080160089A1 (en) * | 2003-10-14 | 2008-07-03 | Medivas, Llc | Vaccine delivery compositions and methods of use |
DE10347710B4 (de) * | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
JP2007512355A (ja) * | 2003-11-21 | 2007-05-17 | アルザ コーポレイション | 開裂性のpegで表面修飾されたリポソーム−dna複合体で媒介される遺伝子送達 |
JP6067954B2 (ja) | 2003-12-19 | 2017-01-25 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill | ナノサイズ物品、及びソフトリソグラフィー又はインプリントリソグラフィーを用いる分離構造の作製方法によって製造されたナノサイズ物品 |
EP1720568A2 (en) | 2004-02-19 | 2006-11-15 | Coley Pharmaceutical Group, Inc. | Immunostimulatory viral rna oligonucleotides |
CA2566506A1 (en) * | 2004-06-01 | 2005-12-15 | Innogenetics N.V. | Peptides for inducing a ctl and/or htl response to hepatitis c virus |
CA2571899A1 (en) | 2004-07-01 | 2006-08-03 | Yale University | Targeted and high density drug loaded polymeric materials |
WO2006014579A2 (en) * | 2004-07-08 | 2006-02-09 | The Regents Of California | Enhancing class i antigen presentation with synthetic sequences |
US8017151B2 (en) * | 2004-09-07 | 2011-09-13 | Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center | Amphiphilic polymer-protein conjugates and methods of use thereof |
EP1793863B1 (en) * | 2004-10-01 | 2017-04-12 | Midatech Ltd. | Nanoparticles comprising antigens and adjuvants capable of stimulating t helper cells |
US20060148009A1 (en) * | 2004-10-12 | 2006-07-06 | Xencor, Inc. | Prediction and assessment of immunogenicity |
MY159370A (en) | 2004-10-20 | 2016-12-30 | Coley Pharm Group Inc | Semi-soft-class immunostimulatory oligonucleotides |
WO2007001448A2 (en) * | 2004-11-04 | 2007-01-04 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
US20090162400A1 (en) * | 2004-12-21 | 2009-06-25 | Powell Thomas J | Compositions of influenza viral proteins and methods of use thereof |
AU2006210792B2 (en) * | 2005-02-01 | 2012-07-26 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Papillomavirus L2 N-terminal peptides for the induction of broadly cross-neutralizing antibodies |
US20060241076A1 (en) | 2005-04-26 | 2006-10-26 | Coley Pharmaceutical Gmbh | Modified oligoribonucleotide analogs with enhanced immunostimulatory activity |
JP2009512421A (ja) * | 2005-08-15 | 2009-03-26 | ヴァクシン インコーポレイテッド | 非複製性ベクターワクチン投与による鳥類への免疫方法 |
US7662949B2 (en) | 2005-11-25 | 2010-02-16 | Coley Pharmaceutical Gmbh | Immunostimulatory oligoribonucleotides |
EP1986609A2 (en) * | 2006-01-26 | 2008-11-05 | University of Massachusetts | Rna silencing agents for use in therapy and nanotransporters for efficient delivery of same |
JP5630998B2 (ja) * | 2006-05-15 | 2014-11-26 | マサチューセッツ インスティテュート オブ テクノロジー | 機能的粒子のためのポリマー |
US20110052697A1 (en) * | 2006-05-17 | 2011-03-03 | Gwangju Institute Of Science & Technology | Aptamer-Directed Drug Delivery |
WO2008033432A2 (en) | 2006-09-12 | 2008-03-20 | Coley Pharmaceutical Group, Inc. | Immune modulation by chemically modified ribonucleosides and oligoribonucleotides |
WO2008036981A1 (en) * | 2006-09-22 | 2008-03-27 | Dana-Farber Cancer Research, Inc. | Methods for treating mica-related disorders |
EP2842570B1 (en) * | 2007-03-07 | 2020-05-06 | UTI Limited Partnership | Compositions and methods for the prevention and treatment of autoimmune conditions |
JP2010523595A (ja) * | 2007-04-04 | 2010-07-15 | マサチューセッツ インスティテュート オブ テクノロジー | ポリ(アミノ酸)ターゲッティング部分 |
CA3016942C (en) * | 2007-05-31 | 2022-09-20 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Hpv epitopes targeted by t cells infiltrating cervical malignancies for use in vaccines |
WO2009026465A2 (en) * | 2007-08-21 | 2009-02-26 | Dynavax Technologies Corporation | Composition and methods of making and using influenza proteins |
US10736848B2 (en) * | 2007-10-12 | 2020-08-11 | Massachusetts Institute Of Technology | Vaccine nanotechnology |
AU2009221419B2 (en) * | 2008-02-01 | 2013-09-26 | Alpha-O Peptides Ag | Self-assembling peptide nanoparticles useful as vaccines |
ES2545886T3 (es) * | 2008-02-14 | 2015-09-16 | Life Sciences Research Partners Vzw | Inmunoterapia dirigida a patógenos intracelulares |
EP2250189A4 (en) * | 2008-02-26 | 2012-07-04 | Univ California | GYLCOPEPTIDES AND METHOD FOR THEIR PREPARATION AND USE |
BRPI1011836A2 (pt) * | 2009-04-21 | 2017-05-16 | Selecta Biosciences Inc | imunonanoterapêuticos que fornecem uma resposta induzida por th1 |
EA028288B1 (ru) * | 2009-05-27 | 2017-10-31 | Селекта Байосайенсиз, Инк. | Наноносители, имеющие компоненты с различными скоростями высвобождения |
EA023897B1 (ru) * | 2009-08-26 | 2016-07-29 | Селекта Байосайенсиз, Инк. | Композиции, которые индуцируют хелперное действие т-клеток |
US20110171248A1 (en) * | 2010-01-08 | 2011-07-14 | Selecta Biosciences, Inc. | Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines |
US20110262491A1 (en) * | 2010-04-12 | 2011-10-27 | Selecta Biosciences, Inc. | Emulsions and methods of making nanocarriers |
US20110293700A1 (en) * | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Nanocarrier compositions with uncoupled adjuvant |
US20120058153A1 (en) * | 2010-08-20 | 2012-03-08 | Selecta Biosciences, Inc. | Synthetic nanocarrier vaccines comprising proteins obtained or derived from human influenza a virus hemagglutinin |
US20120070493A1 (en) * | 2010-08-23 | 2012-03-22 | Selecta Biosciences, Inc. | Targeted multi-epitope dosage forms for induction of an immune response to antigens |
WO2012061717A1 (en) * | 2010-11-05 | 2012-05-10 | Selecta Biosciences, Inc. | Modified nicotinic compounds and related methods |
WO2012092552A1 (en) * | 2010-12-30 | 2012-07-05 | Selecta Biosciences, Inc. | Synthetic nanocarriers with reactive groups that release biologically active agents |
KR20140022025A (ko) * | 2011-03-25 | 2014-02-21 | 셀렉타 바이오사이언시즈, 인크. | 삼투적 매개 방출 합성 나노담체 |
WO2012149405A2 (en) * | 2011-04-29 | 2012-11-01 | Selecta Biosciences, Inc. | Tolerogenic synthetic nanocarriers for regulating innate immune responses |
EP2736537A4 (en) * | 2011-07-29 | 2015-04-15 | Selecta Biosciences Inc | SYNTHETIC NANOTRANSPORTERS FOR THE PRODUCTION OF HUMOROUS AND CYTOTOXIC T-LYMPHOCY (CTL) IMMUNE REACTIONS |
WO2013036297A1 (en) * | 2011-09-06 | 2013-03-14 | Selecta Biosciences, Inc. | Therapeutic protein-specific induced tolerogenic dendritic cells and methods of use |
-
2010
- 2010-08-24 EA EA201270313A patent/EA023897B1/ru not_active IP Right Cessation
- 2010-08-24 KR KR1020177017217A patent/KR101873179B1/ko active IP Right Grant
- 2010-08-24 ES ES10815729.8T patent/ES2641892T3/es active Active
- 2010-08-24 IN IN2589DEN2012 patent/IN2012DN02589A/en unknown
- 2010-08-24 US US12/862,076 patent/US20110110965A1/en not_active Abandoned
- 2010-08-24 EP EP10815729.8A patent/EP2470554B1/en active Active
- 2010-08-24 AU AU2010293059A patent/AU2010293059B2/en not_active Ceased
- 2010-08-24 WO PCT/US2010/002330 patent/WO2011031298A1/en active Application Filing
- 2010-08-24 MX MX2012002357A patent/MX343908B/es active IP Right Grant
- 2010-08-24 CA CA2771863A patent/CA2771863A1/en not_active Abandoned
- 2010-08-24 CN CN201710829621.4A patent/CN107715118A/zh active Pending
- 2010-08-24 KR KR1020127007388A patent/KR20120059572A/ko active Application Filing
- 2010-08-24 BR BR112012003977A patent/BR112012003977A2/pt not_active Application Discontinuation
- 2010-08-24 CN CN2010800428527A patent/CN102574891A/zh active Pending
- 2010-08-24 PL PL10815729T patent/PL2470554T3/pl unknown
- 2010-08-24 JP JP2012526724A patent/JP5933437B2/ja not_active Expired - Fee Related
- 2010-08-24 CN CN201710829622.9A patent/CN107617110A/zh active Pending
- 2010-08-24 EA EA201592264A patent/EA201592264A1/ru unknown
- 2010-08-24 EP EP17171181.5A patent/EP3311833A3/en not_active Withdrawn
-
2012
- 2012-02-22 IL IL218254A patent/IL218254A/en active IP Right Grant
-
2015
- 2015-12-25 JP JP2015252769A patent/JP2016121149A/ja not_active Ceased
-
2017
- 2017-03-02 AU AU2017201438A patent/AU2017201438A1/en not_active Abandoned
- 2017-10-15 IL IL255009A patent/IL255009A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2470554B1 (en) | 2017-06-28 |
WO2011031298A1 (en) | 2011-03-17 |
EP2470554A1 (en) | 2012-07-04 |
ES2641892T3 (es) | 2017-11-14 |
MX343908B (es) | 2016-11-28 |
JP2013503159A (ja) | 2013-01-31 |
IL218254A (en) | 2017-11-30 |
BR112012003977A2 (pt) | 2017-06-06 |
KR20170076804A (ko) | 2017-07-04 |
KR20120059572A (ko) | 2012-06-08 |
EP3311833A2 (en) | 2018-04-25 |
PL2470554T3 (pl) | 2018-02-28 |
EA201592264A1 (ru) | 2016-08-31 |
AU2010293059B2 (en) | 2017-03-16 |
AU2010293059A1 (en) | 2012-03-08 |
CN102574891A (zh) | 2012-07-11 |
CN107715118A (zh) | 2018-02-23 |
EA023897B1 (ru) | 2016-07-29 |
CA2771863A1 (en) | 2011-03-17 |
AU2017201438A1 (en) | 2017-03-16 |
MX2012002357A (es) | 2012-04-10 |
CN107617110A (zh) | 2018-01-23 |
KR101873179B1 (ko) | 2018-06-29 |
IL255009A0 (en) | 2017-12-31 |
EA201270313A1 (ru) | 2012-09-28 |
US20110110965A1 (en) | 2011-05-12 |
JP5933437B2 (ja) | 2016-06-08 |
EP3311833A3 (en) | 2018-07-25 |
EP2470554A4 (en) | 2014-05-07 |
IL218254A0 (en) | 2012-04-30 |
JP2016121149A (ja) | 2016-07-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2012DN02589A (sl) | ||
PH12018501517B1 (en) | Neisseria meningitidis compositions and methods thereof | |
EA201792245A1 (ru) | Биоконъюгаты и их применения | |
EP3533461A3 (en) | Prame derived peptides and immunogenic compositions comprising these | |
WO2009088401A3 (en) | Immunostimulatory combinations of tlr3 ligands with tlr2 and/or tlr9 agonists and methods of use | |
UA97095C2 (ru) | Противораковая вакцина, которая содержит опухолевоассоциированный пептид, который связывается с молекулами лейкоцитарного антигена человека (hla) класса i или ii, и ее применение в производстве лекарственного средства | |
MX2007015935A (es) | Agentes y metodos basados en el uso del dominio eda de la fibronectina. | |
UA103774C2 (uk) | Модифіковані поліпептиди бичачого гранулоцитарного колонієстимулювального фактора (g-csf) та їх застосування | |
GB0710529D0 (en) | Vaccine | |
EP2166845A4 (en) | ALPHA CONNEXIN C TERMINAL (ACT) PEPTIDES FOR THE TREATMENT OF AGE-RELATED MACULAR AGENCY | |
MX2010010457A (es) | Vectores recombinantes de rinovirus. | |
EP2402364A3 (en) | A nonapeptide with anti-tumour activity | |
HK1142803A1 (en) | Compositions comprising myelin basic protein peptides and medical uses thereof | |
MY148915A (en) | An extended-release composition comprising a somatostatin derivative in microparticles | |
NZ594268A (en) | Grass peptides for vaccine | |
EP2552462A4 (en) | CCN3 PEPTIDES AND ANALOGS THEREOF FOR THERAPEUTIC USE | |
PH12015501033A1 (en) | Peptides | |
WO2014039074A3 (en) | Therapeutic compositions and related methods | |
MX2011012270A (es) | Peptidos de factor vii tolerogenico. | |
WO2009095646A3 (en) | Peptides from factor viii | |
EA201200889A1 (ru) | Пептид | |
GB0818080D0 (en) | Immunogenic peptides | |
EA200870188A1 (ru) | Связывающие fgf2 пептиды и их применение | |
WO2009147384A3 (en) | Peptides derived from the neural-restrictive silencer factor rest and use thereof | |
MY178220A (en) | Gold binding polypeptide |