IN2012DN02301A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02301A
IN2012DN02301A IN2301DEN2012A IN2012DN02301A IN 2012DN02301 A IN2012DN02301 A IN 2012DN02301A IN 2301DEN2012 A IN2301DEN2012 A IN 2301DEN2012A IN 2012DN02301 A IN2012DN02301 A IN 2012DN02301A
Authority
IN
India
Prior art keywords
formula
compound
resulting
6alkyl
alkylating
Prior art date
Application number
Other languages
English (en)
Inventor
Augustinus De Kock Herman
Ferdinand Maria Filliers Walter
Albert Alex Aelterman Wim
Original Assignee
Janssen R & D Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen R & D Ireland filed Critical Janssen R & D Ireland
Publication of IN2012DN02301A publication Critical patent/IN2012DN02301A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN2301DEN2012 2003-09-30 2004-09-30 IN2012DN02301A (https=)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03103630 2003-09-30
US50799603P 2003-10-02 2003-10-02
PCT/EP2004/052382 WO2005030739A1 (en) 2003-09-30 2004-09-30 Methods for the preparation of benzoxazole sulfonamide compounds and intermediates thereof

Publications (1)

Publication Number Publication Date
IN2012DN02301A true IN2012DN02301A (https=) 2015-08-14

Family

ID=34395298

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2301DEN2012 IN2012DN02301A (https=) 2003-09-30 2004-09-30

Country Status (24)

Country Link
US (1) US20070123574A1 (https=)
EP (1) EP1670773B1 (https=)
JP (1) JP4919802B2 (https=)
KR (1) KR101090102B1 (https=)
CN (1) CN1860107B (https=)
AP (1) AP1985A (https=)
AT (1) ATE353323T1 (https=)
AU (1) AU2004276017B2 (https=)
BR (1) BRPI0414916A (https=)
CA (1) CA2537877C (https=)
DE (1) DE602004004674T2 (https=)
DK (1) DK1670773T3 (https=)
EA (1) EA011891B1 (https=)
ES (1) ES2281828T3 (https=)
IL (1) IL173891A0 (https=)
IN (1) IN2012DN02301A (https=)
MX (1) MXPA06003575A (https=)
NO (1) NO20061951L (https=)
NZ (1) NZ546279A (https=)
PL (1) PL1670773T3 (https=)
PT (1) PT1670773E (https=)
SI (1) SI1670773T1 (https=)
WO (1) WO2005030739A1 (https=)
ZA (1) ZA200602603B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR053845A1 (es) * 2005-04-15 2007-05-23 Tibotec Pharm Ltd 5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450
US8575186B2 (en) 2009-10-05 2013-11-05 Albany Molecular Research, Inc. Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
AU2012207335A1 (en) 2011-01-19 2013-07-25 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-HT6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
WO2014194519A1 (en) 2013-06-07 2014-12-11 Merck Sharp & Dohme Corp. Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968942A (en) * 1992-08-25 1999-10-19 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
CN1530372A (zh) * 1995-03-10 2004-09-22 G.D.ɪ����˾ 杂环羰基氨基酸羟乙氨基磺酰胺逆转录病毒蛋白酶抑制剂
AU7722296A (en) * 1995-11-15 1997-06-05 G.D. Searle & Co. Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
EP1208092B1 (en) * 2000-04-07 2006-06-21 Samsung Electronics Co., Ltd. Sulfonamide derivative as a matrix metalloproteinase inhibitor
US6455738B1 (en) * 2000-07-13 2002-09-24 Rhodia Chimie Process for the sulfonation of an aromatic compound
ES2275866T3 (es) * 2001-02-14 2007-06-16 Tibotec Pharmaceuticals Ltd. 2-(aminosustituido)-benzotiazol-sulfonamidas de amplio esprecto inhibidoras de la proteasa de vih.
EA009590B1 (ru) * 2001-05-11 2008-02-28 Тиботек Фармасьютикалз Лтд. 2-аминобензоксазолсульфонамидные ингибиторы вич-протеазы широкого спектра
TWI286476B (en) * 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
MY142238A (en) * 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors

Also Published As

Publication number Publication date
EP1670773A1 (en) 2006-06-21
CN1860107B (zh) 2013-08-21
DE602004004674T2 (de) 2007-11-22
AU2004276017A1 (en) 2005-04-07
PT1670773E (pt) 2007-05-31
CA2537877C (en) 2015-03-17
DE602004004674D1 (de) 2007-03-22
AU2004276017B2 (en) 2010-08-19
NZ546279A (en) 2008-09-26
KR101090102B1 (ko) 2011-12-07
EA011891B1 (ru) 2009-06-30
ZA200602603B (en) 2008-05-28
IL173891A0 (en) 2006-07-05
ES2281828T3 (es) 2007-10-01
JP4919802B2 (ja) 2012-04-18
EA200600699A1 (ru) 2006-08-25
BRPI0414916A (pt) 2006-11-07
MXPA06003575A (es) 2006-06-05
CA2537877A1 (en) 2005-04-07
AP1985A (en) 2009-03-30
WO2005030739A1 (en) 2005-04-07
AP2006003603A0 (en) 2006-04-30
JP2007507468A (ja) 2007-03-29
NO20061951L (no) 2006-05-02
CN1860107A (zh) 2006-11-08
SI1670773T1 (sl) 2007-06-30
EP1670773B1 (en) 2007-02-07
KR20060092224A (ko) 2006-08-22
PL1670773T3 (pl) 2007-06-29
DK1670773T3 (da) 2007-05-29
ATE353323T1 (de) 2007-02-15
US20070123574A1 (en) 2007-05-31

Similar Documents

Publication Publication Date Title
MY138525A (en) Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
BG103413A (en) Derivatives of sulphinic acid, their production and application
GB9801690D0 (en) Therapeutic agents
WO2002049641A3 (en) Anti-endoparasitic amidoacetonitrils
SE0004245D0 (sv) Novel compounds and their use
WO1999000373A8 (en) Benzimidazole derivatives
NZ505103A (en) Phenylaminoalkylcarboxylic acid derivatives useful as beta 3 adrenoceptor stimulants
IN2012DN02301A (https=)
WO2000046210A3 (en) New process for preparing pesticidal intermediates
TW200621685A (en) Hydroxynaphthoic acid hydrazide compound and method for preparing the same
IT1293777B1 (it) Processo per la preparazione di tetraazamacrocicli
MY130488A (en) Process for preparing 3,3',6,6'-tetraalkyl-2,2'-biphenols and 3,3',6,6'-tetraalkyl-5,5'-dihalo-2,2'-biphenols
WO2002060878A1 (fr) Derives de benzimidazolidinone
IL154466A0 (en) Process for preparing a substituted imidazopyridine compound
MXPA02001406A (es) Heterociclilos-2h-cromenos substituidos.
WO2004024727A3 (en) Synthesis of indolizines
WO2004024681A3 (fr) NOUVEAUX COMPOSES COMPRENANT UN GROUPEMENT THIOCARBONYLSULFANYLE UTILES POUR LA SYNTHESE DE COMPOSES α-PERFLUOROALKYLAMINES PAR VOIE RADICALAIRE
GB9920959D0 (en) Novel process
SE0101323D0 (sv) New process
EP0753514A4 (en) ALKYLENEDIAMINE DERIVATIVES
SE0000382D0 (sv) New process
DE60313124D1 (de) Verfahren zur herstellung einer 1,2,3-triazolverbindung
WO2001010862A3 (de) Substituierte heterocyclylbenzofurane
NO20053117L (no) Cyklopenta[c]isoksazol-3-aminer anvendt som materialbeskyttelsesmidler..
CA2390934A1 (en) Process for producing benzylamine compound