IN2012DN02129A - - Google Patents

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Publication number
IN2012DN02129A
IN2012DN02129A IN2129DEN2012A IN2012DN02129A IN 2012DN02129 A IN2012DN02129 A IN 2012DN02129A IN 2129DEN2012 A IN2129DEN2012 A IN 2129DEN2012A IN 2012DN02129 A IN2012DN02129 A IN 2012DN02129A
Authority
IN
India
Prior art keywords
brightfield
image
generating
biological sample
fluorescent images
Prior art date
Application number
Other languages
English (en)
Inventor
Can Ali
j gerdes Michael
O Bello Musodiq
Li Qing
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Electric filed Critical Gen Electric
Publication of IN2012DN02129A publication Critical patent/IN2012DN02129A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00Image enhancement or restoration
    • G06T5/50Image enhancement or restoration using two or more images, e.g. averaging or subtraction
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693Acquisition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • G01N2021/6423Spectral mapping, video display
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10064Fluorescence image
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20212Image combination
    • G06T2207/20221Image fusion; Image merging
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Multimedia (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Processing Or Creating Images (AREA)
IN2129DEN2012 2009-09-29 2010-09-29 IN2012DN02129A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/569,396 US8269827B2 (en) 2009-09-29 2009-09-29 System and methods for mapping fluorescent images into a bright field color space
PCT/SE2010/051046 WO2011040872A1 (en) 2009-09-29 2010-09-29 System and method for generating a brightfield image using fluorescent images

Publications (1)

Publication Number Publication Date
IN2012DN02129A true IN2012DN02129A (pt) 2015-08-21

Family

ID=43779911

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2129DEN2012 IN2012DN02129A (pt) 2009-09-29 2010-09-29

Country Status (10)

Country Link
US (1) US8269827B2 (pt)
EP (1) EP2483668A4 (pt)
JP (1) JP5631999B2 (pt)
KR (1) KR20120079080A (pt)
CN (1) CN102575990B (pt)
AU (1) AU2010301166A1 (pt)
CA (1) CA2773268A1 (pt)
IN (1) IN2012DN02129A (pt)
RU (1) RU2012111453A (pt)
WO (1) WO2011040872A1 (pt)

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US8725237B2 (en) 2012-03-19 2014-05-13 Genetic Innovations, Inc. Devices, systems, and methods for virtual staining
AU2013240127B2 (en) * 2012-03-30 2018-07-12 Leica Microsystems Cms Gmbh Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample
RU2014137125A (ru) * 2012-03-30 2016-05-27 Клариент Дайагностик Сервисез, Инк. Способы формирования изображения биологического образца
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US20150105283A1 (en) 2012-05-30 2015-04-16 Clarient Diagnostics Services, Inc. Multiplexed diagnosis method for classical hodgkin lymphoma
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KR20160117440A (ko) * 2013-12-31 2016-10-10 메모리얼 슬로안-케터링 캔서 센터 실시간 형광 소스들의 다채널 이미징을 위한 시스템들, 방법들 및 장치
WO2015195642A1 (en) * 2014-06-16 2015-12-23 Siemens Healthcare Diagnostics Inc. Analyzing digital holographic microscopy data for hematology applications
US10614287B2 (en) 2014-06-16 2020-04-07 Siemens Healthcare Diagnostics Inc. Virtual staining of cells in digital holographic microscopy images using general adversarial networks
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JP6702339B2 (ja) * 2015-12-24 2020-06-03 コニカミノルタ株式会社 画像処理装置及びプログラム
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JP6901072B2 (ja) * 2017-08-30 2021-07-14 学校法人 埼玉医科大学 画像処理装置、画像処理方法、画像処理プログラム
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WO2019191697A1 (en) 2018-03-30 2019-10-03 The Regents Of The University Of California Method and system for digital staining of label-free fluorescence images using deep learning
CN110346291A (zh) * 2018-04-03 2019-10-18 锐准医光股份有限公司 一种生物样本的影像合成方法及采用该方法的光学系统
TWI683283B (zh) 2018-04-03 2020-01-21 薩摩亞商銳準醫光股份有限公司 一種生物樣本之影像合成方法及採用該方法之光學系統
US12106552B2 (en) 2018-07-19 2024-10-01 The Regents Of The University Of California Method and system for digital staining of label-free phase images using deep learning
AU2019416121A1 (en) * 2018-12-28 2021-05-20 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample and systems for same
JP7470339B2 (ja) * 2019-03-06 2024-04-18 学校法人 埼玉医科大学 染色画像推定器学習装置、画像処理装置、染色画像推定器学習方法、画像処理方法、染色画像推定器学習プログラム、及び、画像処理プログラム
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Also Published As

Publication number Publication date
EP2483668A4 (en) 2017-11-15
KR20120079080A (ko) 2012-07-11
US20110074944A1 (en) 2011-03-31
AU2010301166A1 (en) 2012-03-29
EP2483668A1 (en) 2012-08-08
US8269827B2 (en) 2012-09-18
RU2012111453A (ru) 2013-11-20
WO2011040872A1 (en) 2011-04-07
JP2013506129A (ja) 2013-02-21
CA2773268A1 (en) 2011-04-07
JP5631999B2 (ja) 2014-11-26
CN102575990B (zh) 2015-06-17
CN102575990A (zh) 2012-07-11

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