IN2012DN00549A - - Google Patents
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- Publication number
- IN2012DN00549A IN2012DN00549A IN549DEN2012A IN2012DN00549A IN 2012DN00549 A IN2012DN00549 A IN 2012DN00549A IN 549DEN2012 A IN549DEN2012 A IN 549DEN2012A IN 2012DN00549 A IN2012DN00549 A IN 2012DN00549A
- Authority
- IN
- India
- Prior art keywords
- subject
- activity
- relates
- compounds
- hif levels
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 230000007954 hypoxia Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910089274 | 2009-07-15 | ||
| PCT/CN2010/001057 WO2011006355A1 (en) | 2009-07-15 | 2010-07-14 | Compounds as hypoxia mimetics, and compositions, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN00549A true IN2012DN00549A (ro) | 2015-06-12 |
Family
ID=43448908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN549DEN2012 IN2012DN00549A (ro) | 2009-07-15 | 2010-07-14 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8742138B2 (ro) |
| EP (1) | EP2454249B1 (ro) |
| JP (1) | JP5847710B2 (ro) |
| KR (1) | KR20120065311A (ro) |
| CN (1) | CN102164905B (ro) |
| AU (1) | AU2010273101B2 (ro) |
| CA (1) | CA2767911C (ro) |
| ES (1) | ES2702524T3 (ro) |
| IL (1) | IL217531A0 (ro) |
| IN (1) | IN2012DN00549A (ro) |
| SG (1) | SG177598A1 (ro) |
| WO (1) | WO2011006355A1 (ro) |
| ZA (1) | ZA201200293B (ro) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104024227B8 (zh) | 2011-07-22 | 2025-07-29 | 北京贝美拓新药研发有限公司 | 抑制脯氨酸羟化酶活性的化合物的晶型及其应用 |
| JP2014523917A (ja) * | 2011-07-29 | 2014-09-18 | ベイジン ベータ ファーマシューティカルズ カンパニー， リミテッド | 低酸素模倣剤としての化合物の安定な多形体、およびその使用 |
| ES2898476T3 (es) | 2014-09-02 | 2022-03-07 | Sunshine Lake Pharma Co Ltd | Compuesto de quinolona y uso del mismo |
| WO2016111523A2 (ko) * | 2015-01-05 | 2016-07-14 | 국립암센터 | HNF4-α 길항제 및 이의 용도 |
| WO2017027839A1 (en) * | 2015-08-13 | 2017-02-16 | Somagenics, Inc. | Methods and compositions of short small hairpin rnas and micrornas for wound healing |
| CN113004271A (zh) | 2017-05-09 | 2021-06-22 | 杭州安道药业有限公司 | 吲哚嗪衍生物及其在医药上的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003228348A1 (en) * | 2002-03-20 | 2003-10-08 | John T. Fassett | Induction of hepatocyte proliferation in vitro by inhibition of cell cycle inhibitors |
| JP2009506068A (ja) * | 2005-08-25 | 2009-02-12 | エモリー・ユニバーシティ | Ｈｉｆ阻害剤 |
| WO2007038571A2 (en) * | 2005-09-26 | 2007-04-05 | Smithkline Beecham Corporation | Prolyl hydroxylase antagonists |
| AU2006326662B2 (en) | 2005-12-09 | 2011-07-28 | Amgen Inc. | Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof |
| TW200808793A (en) * | 2006-03-07 | 2008-02-16 | Smithkline Beecham Corp | Prolyl hydroxylase inhibitors |
| WO2008119744A1 (en) | 2007-03-29 | 2008-10-09 | Novartis Ag | Heterocyclic spiro-compounds |
| US8324405B2 (en) * | 2008-02-05 | 2012-12-04 | Fibrogen, Inc. | Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors |
| WO2010024908A1 (en) * | 2008-08-26 | 2010-03-04 | Fibrogen, Inc. | Methods for treatment of multiple sclerosis |
-
2010
- 2010-07-14 CN CN201080002367.7A patent/CN102164905B/zh not_active Expired - Fee Related
- 2010-07-14 IN IN549DEN2012 patent/IN2012DN00549A/en unknown
- 2010-07-14 WO PCT/CN2010/001057 patent/WO2011006355A1/en not_active Ceased
- 2010-07-14 US US13/384,097 patent/US8742138B2/en active Active
- 2010-07-14 AU AU2010273101A patent/AU2010273101B2/en not_active Ceased
- 2010-07-14 ES ES10799353T patent/ES2702524T3/es active Active
- 2010-07-14 SG SG2012001806A patent/SG177598A1/en unknown
- 2010-07-14 JP JP2012519871A patent/JP5847710B2/ja not_active Expired - Fee Related
- 2010-07-14 EP EP10799353.7A patent/EP2454249B1/en not_active Not-in-force
- 2010-07-14 KR KR1020127001420A patent/KR20120065311A/ko not_active Ceased
- 2010-07-14 CA CA2767911A patent/CA2767911C/en not_active Expired - Fee Related
-
2012
- 2012-01-12 IL IL217531A patent/IL217531A0/en unknown
- 2012-01-13 ZA ZA2012/00293A patent/ZA201200293B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010273101A2 (en) | 2012-03-15 |
| EP2454249A1 (en) | 2012-05-23 |
| CN102164905A (zh) | 2011-08-24 |
| SG177598A1 (en) | 2012-02-28 |
| US20120172399A1 (en) | 2012-07-05 |
| CA2767911C (en) | 2016-03-29 |
| EP2454249A4 (en) | 2012-12-12 |
| JP5847710B2 (ja) | 2016-01-27 |
| WO2011006355A1 (en) | 2011-01-20 |
| US8742138B2 (en) | 2014-06-03 |
| EP2454249B1 (en) | 2018-09-19 |
| IL217531A0 (en) | 2012-02-29 |
| ES2702524T3 (es) | 2019-03-01 |
| CN102164905B (zh) | 2014-04-30 |
| KR20120065311A (ko) | 2012-06-20 |
| JP2012532897A (ja) | 2012-12-20 |
| AU2010273101A1 (en) | 2012-02-02 |
| ZA201200293B (en) | 2012-09-26 |
| HK1161234A1 (en) | 2012-08-24 |
| CA2767911A1 (en) | 2011-01-20 |
| AU2010273101B2 (en) | 2016-02-25 |
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