IN2012DN00361A - - Google Patents

Info

Publication number
IN2012DN00361A
IN2012DN00361A IN361DEN2012A IN2012DN00361A IN 2012DN00361 A IN2012DN00361 A IN 2012DN00361A IN 361DEN2012 A IN361DEN2012 A IN 361DEN2012A IN 2012DN00361 A IN2012DN00361 A IN 2012DN00361A
Authority
IN
India
Prior art keywords
spilanthol
configurations
amide ester
group
alkyl group
Prior art date
Application number
Inventor
Tanaka Shigeru
Ishida Kenya
Yagi Kenji
Ujihara Hideo
Original Assignee
Takasago Perfumery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takasago Perfumery Co Ltd filed Critical Takasago Perfumery Co Ltd
Publication of IN2012DN00361A publication Critical patent/IN2012DN00361A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/56—Flavouring or bittering agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/202—Aliphatic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0007—Aliphatic compounds

Abstract

Provided is an amide ester that is useful as an intermediate manufacturing product for an aroma compound such as spilanthol or the like. Also provided is a spilanthol manufacturing method using said amide ester. High-purity spilanthol can be manufactured by reacting an amide ester represented by general formula (1) with a basic compound. (In the formula, R1 represents a phenyl group that may be substituted with a C1-6 alkyl group and either a C1-4 alkyl group, a C1-4 alkoxy group, or a halogen atom; R2 represents a C1-8 hydrocarbon group; and the wavy lines represent cis configurations, trans configurations, or a mixture of the two configurations.)
IN361DEN2012 2009-07-14 2010-07-14 IN2012DN00361A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009165530 2009-07-14
PCT/JP2010/061912 WO2011007807A1 (en) 2009-07-14 2010-07-14 Method for manufacturing spilanthol and intermediate manufacturing product therefor

Publications (1)

Publication Number Publication Date
IN2012DN00361A true IN2012DN00361A (en) 2015-05-22

Family

ID=43449415

Family Applications (1)

Application Number Title Priority Date Filing Date
IN361DEN2012 IN2012DN00361A (en) 2009-07-14 2010-07-14

Country Status (7)

Country Link
US (1) US9029593B2 (en)
EP (1) EP2455363B1 (en)
JP (1) JP5587313B2 (en)
CN (1) CN102471238B (en)
ES (1) ES2512240T3 (en)
IN (1) IN2012DN00361A (en)
WO (1) WO2011007807A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2986001B1 (en) 2012-01-24 2014-08-15 Robertet Sa NOVEL METHOD OF CONCENTRATING SPILANTHOL AND / OR ITS ISOMERS AND / OR HOMOLOGISTS
WO2013140973A1 (en) * 2012-03-23 2013-09-26 大正製薬株式会社 Beverage
TW201625140A (en) * 2014-08-29 2016-07-16 San Ei Gen Ffi Inc Additive for orally administered composition
BR102016017871B1 (en) * 2016-07-29 2023-03-21 Universidade Estadual De Campinas - Unicamp PROCESS FOR OBTAINING SPILANTHOL AND ANALOGS, SPILANTHOL AND ANALOGS OBTAINED

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0790294A (en) * 1993-09-20 1995-04-04 Lion Corp Essential oil having high spilanthol content, production thereof and composition for oral cavity blended with essential oil having high spilanthol content
ATE344032T1 (en) * 2003-06-13 2006-11-15 Ecopia Biosciences Inc POLYENOXAZOLES WITH ANTITUMOR EFFECT AND METHOD FOR THE PRODUCTION THEREOF USING A STREPTOMYCES STRAIN
FR2865131B1 (en) * 2004-01-15 2007-08-24 Gattefosse Ets Sa USE OF AN EXTRACT OF ACMELLA OLERACEA FOR ITS BOTOX LIKE EFFECT IN AN ANTI-WRINKLE COSMETIC COMPOSITION
JP4679132B2 (en) * 2004-12-20 2011-04-27 小川香料株式会社 Carbonated beverage additive
JP4688517B2 (en) * 2005-02-15 2011-05-25 小川香料株式会社 Taste improver for high-intensity sweeteners
JP4530906B2 (en) 2005-04-25 2010-08-25 小川香料株式会社 Flavor enhancer for food and drink
JP4508932B2 (en) 2005-04-25 2010-07-21 小川香料株式会社 Taste enhancer, flavor containing the taste enhancer, and food and drink containing the flavor
US8828469B2 (en) * 2007-11-08 2014-09-09 Symrise Ag Use of alkamides for masking an unpleasant flavor
CN101910116B (en) * 2008-01-18 2013-06-19 高砂香料工业株式会社 Method for production of (2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide (spilanthol), and foods, beverages, cosmetics and pharmaceutical preparations each comprising the compound

Also Published As

Publication number Publication date
EP2455363A1 (en) 2012-05-23
ES2512240T3 (en) 2014-10-23
EP2455363A4 (en) 2012-12-26
US9029593B2 (en) 2015-05-12
JPWO2011007807A1 (en) 2012-12-27
JP5587313B2 (en) 2014-09-10
CN102471238A (en) 2012-05-23
CN102471238B (en) 2014-04-02
US20120116116A1 (en) 2012-05-10
WO2011007807A1 (en) 2011-01-20
EP2455363B1 (en) 2014-10-01

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