IN185730B - - Google Patents

Info

Publication number
IN185730B
IN185730B IN101CA1999A IN185730B IN 185730 B IN185730 B IN 185730B IN 101CA1999 A IN101CA1999 A IN 101CA1999A IN 185730 B IN185730 B IN 185730B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Brid Burruano
Michael R Hoy
Richard D Bruce
John D Higgins Iii
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/025,952 external-priority patent/US6110502A/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of IN185730B publication Critical patent/IN185730B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seeds, Soups, And Other Foods (AREA)
IN101CA1999 1998-02-19 1999-02-10 IN185730B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/025,952 US6110502A (en) 1998-02-19 1998-02-19 Method for producing water dispersible sterol formulations
US09/185,788 US6054144A (en) 1998-02-19 1998-11-04 Method for producing water dispersible sterol formulations

Publications (1)

Publication Number Publication Date
IN185730B true IN185730B (el) 2001-04-14

Family

ID=26700515

Family Applications (1)

Application Number Title Priority Date Filing Date
IN101CA1999 IN185730B (el) 1998-02-19 1999-02-10

Country Status (16)

Country Link
EP (1) EP0947197B1 (el)
JP (1) JPH11313644A (el)
CN (1) CN1161123C (el)
AT (1) ATE264683T1 (el)
AU (1) AU760314B2 (el)
BR (1) BR9902325A (el)
CZ (1) CZ298506B6 (el)
DE (1) DE69916522T2 (el)
DK (1) DK0947197T3 (el)
ES (1) ES2216439T3 (el)
HU (1) HUP9900434A2 (el)
IN (1) IN185730B (el)
NO (1) NO990747L (el)
NZ (1) NZ334189A (el)
PL (1) PL192906B1 (el)
PT (1) PT947197E (el)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE512958C2 (sv) * 1998-04-30 2000-06-12 Triple Crown Ab Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning
US6123978A (en) 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6376481B2 (en) * 1998-09-02 2002-04-23 Mcneil-Ppc, Inc. Sterol esters in tableted solid dosage forms
US6677327B1 (en) 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
GB0021498D0 (en) * 2000-09-01 2000-10-18 Novartis Nutrition Ag New formulation
AU2005234649B2 (en) * 2000-09-01 2008-01-17 Forbes Medi-Tech, Inc. Water-dispersible encapsulated sterols
KR20020026053A (ko) 2000-09-30 2002-04-06 노승권 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료
GB0104074D0 (en) * 2001-02-19 2001-04-04 Novartis Ag New composition
US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
CA2454636A1 (en) 2001-07-24 2003-02-06 Cargill, Incorporated Process for isolating phenolic compounds
CN1297216C (zh) * 2002-03-20 2007-01-31 尤金科学(有限)公司 植物甾醇与乳化剂的混合粉末及其制备方法
US6623780B1 (en) 2002-03-26 2003-09-23 Cargill, Inc. Aqueous dispersible sterol product
CA2481705A1 (en) * 2002-04-10 2003-10-23 Thomas P. Binder Hydrothermically processed compositions containing phytosterols
DK1549159T3 (da) 2002-06-12 2009-03-02 Coca Cola Co Drikkevarer indeholdende plantesteroler
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
US7732000B2 (en) 2002-06-20 2010-06-08 General Mills, Inc. Food intermediate having sequestered phytosteryl esters in a polysaccharide matrix
US20060035009A1 (en) * 2004-08-10 2006-02-16 Kraft Foods Holdings, Inc. Compositions and processes for water-dispersible phytosterols and phytostanols
AU2005324945A1 (en) * 2005-01-14 2006-07-20 Unilever Plc Sachets comprising plant sterol
DE102005008445A1 (de) 2005-02-24 2006-08-31 Cognis Ip Management Gmbh Zuckerhaltige Sterolfeststoffdispersionen
DE102005039835A1 (de) * 2005-08-23 2007-03-01 Cognis Ip Management Gmbh Pulverförmige Sterolformulierungen mit Kolloidbildnern
CN111529500B (zh) * 2020-06-28 2021-09-24 江西谷物源食品有限公司 一种提高谷维素溶解度的药物组合物及其制备方法
CN112618665B (zh) * 2020-12-19 2022-06-14 杭州益品新五丰药业有限公司 一种提高免疫反应的糠甾醇-谷维素联合用药制剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881005A (en) * 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
US4195084A (en) * 1977-01-07 1980-03-25 Eli Lilly And Company Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof
DE3829643A1 (de) * 1988-09-01 1990-03-15 Roecar Holdings Nv Phyto- und zoosterole und deren derivate mit verbesserter wasserloeslichkeit
WO1991001139A1 (de) * 1989-07-21 1991-02-07 Marigen S.A. Sterole, deren fettsäureester und glucoside; verfahren zu ihrer herstellung; spontan dispergierbare mittel mit diesen verbindungen, sowie ihre verwendung zur behandlung von tumoren
CH681153A5 (de) * 1991-01-28 1993-01-29 Marigen S.A. Neue sterolester- und sterolphosphorverbindungen.
DE69127207T2 (de) * 1991-05-03 1998-01-22 Raision Tehtaat Oy Ab Substanz zur absenkung eines hohen cholesterolspiegels im serum und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
CN1161123C (zh) 2004-08-11
PL192906B1 (pl) 2006-12-29
PT947197E (pt) 2004-08-31
NO990747L (no) 1999-08-20
NO990747D0 (no) 1999-02-18
DE69916522T2 (de) 2005-07-21
CZ54799A3 (cs) 1999-09-15
AU760314B2 (en) 2003-05-15
HUP9900434A2 (hu) 2001-06-28
DK0947197T3 (da) 2004-07-26
DE69916522D1 (de) 2004-05-27
NZ334189A (en) 1999-07-29
ATE264683T1 (de) 2004-05-15
JPH11313644A (ja) 1999-11-16
AU1735899A (en) 2000-06-08
BR9902325A (pt) 2000-04-11
ES2216439T3 (es) 2004-10-16
HU9900434D0 (en) 1999-04-28
CN1232668A (zh) 1999-10-27
CZ298506B6 (cs) 2007-10-24
PL331546A1 (en) 1999-08-30
EP0947197A1 (en) 1999-10-06
EP0947197B1 (en) 2004-04-21

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