IL99628A - Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them - Google Patents
Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing themInfo
- Publication number
- IL99628A IL99628A IL9962891A IL9962891A IL99628A IL 99628 A IL99628 A IL 99628A IL 9962891 A IL9962891 A IL 9962891A IL 9962891 A IL9962891 A IL 9962891A IL 99628 A IL99628 A IL 99628A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- compound
- group
- amino acid
- give
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL9962891A IL99628A (en) | 1991-10-02 | 1991-10-02 | Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them |
JP30434792A JP3509029B2 (ja) | 1991-10-02 | 1992-10-02 | 生物活性環化ポリペプチド |
DE69230610T DE69230610T2 (de) | 1991-10-02 | 1992-10-02 | Peptide mit zyklischen Hauptketten, deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
EP92309016A EP0564739B1 (en) | 1991-10-02 | 1992-10-02 | Backbone cyclic peptides, processes for their preparation and pharmaceutical compositions containing them |
AT92309016T ATE189228T1 (de) | 1991-10-02 | 1992-10-02 | Peptide mit zyklischen hauptketten, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen |
US08/444,135 US5723575A (en) | 1991-10-02 | 1995-05-18 | Process for the preparation of backbone cyclic peptides |
US08/569,042 US6117974A (en) | 1991-10-02 | 1995-12-07 | Libraries of backbone-cyclized peptidomimetics |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL9962891A IL99628A (en) | 1991-10-02 | 1991-10-02 | Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
IL99628A0 IL99628A0 (en) | 1992-08-18 |
IL99628A true IL99628A (en) | 2004-07-25 |
Family
ID=11062920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9962891A IL99628A (en) | 1991-10-02 | 1991-10-02 | Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them |
Country Status (6)
Country | Link |
---|---|
US (1) | US5723575A (es) |
EP (1) | EP0564739B1 (es) |
JP (1) | JP3509029B2 (es) |
AT (1) | ATE189228T1 (es) |
DE (1) | DE69230610T2 (es) |
IL (1) | IL99628A (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6117974A (en) * | 1991-10-02 | 2000-09-12 | Peptor Limited | Libraries of backbone-cyclized peptidomimetics |
US6872803B1 (en) | 1993-09-21 | 2005-03-29 | Kyowa Hakko Kogyo Co., Ltd. | Peptides |
IL109943A (en) | 1994-06-08 | 2006-08-01 | Develogen Israel Ltd | Conformationally constrained backbone cyclized peptide analogs |
AU724386B2 (en) * | 1994-06-08 | 2000-09-21 | Peptor Ltd | Conformationally constrained backbone cyclized peptide analogs |
US6407059B1 (en) | 1994-06-08 | 2002-06-18 | Peptor Limited | Conformationally constrained backbone cyclized peptide analogs |
US6051554A (en) * | 1995-06-07 | 2000-04-18 | Peptor Limited | Conformationally constrained backbone cyclized somatostatin analogs |
US5770687A (en) * | 1995-06-07 | 1998-06-23 | Peptor Limited | Comformationally constrained backbone cyclized somatostatin analogs |
US6841533B1 (en) | 1995-12-07 | 2005-01-11 | Peptor Limited | Conformationally constrained backbone cyclized interleukin-6 antagonists |
US6117641A (en) | 1996-04-11 | 2000-09-12 | Mitotix, Inc. | Assays and reagents for identifying anti-fungal agents and uses related thereto |
US6727082B1 (en) | 1996-04-11 | 2004-04-27 | Gpc Biotech Inc. | Assays and reagents for identifying anti-fungal agents, and uses related thereto |
AU717165B2 (en) | 1996-04-11 | 2000-03-16 | Gpc Biotech Inc. | Assays and reagents for identifying anti-fungal agents, and uses related thereto |
US6355613B1 (en) | 1996-07-31 | 2002-03-12 | Peptor Limited | Conformationally constrained backbone cyclized somatostatin analogs |
IL122343A0 (en) * | 1997-11-27 | 1998-04-05 | Yissum Res Dev Co | Inhibition of nuclear import by backbone cyclic peptide analogs |
AU1254299A (en) * | 1997-12-02 | 1999-06-16 | State Of Israel - Ministry Of Agriculture | Backbone cyclic peptide fragments and their analogs derived from pban 1-33, use ful as insecticides |
WO1999031121A2 (en) | 1997-12-15 | 1999-06-24 | Peptor Ltd. | Branched building units for synthesizing cyclic peptides |
US6632429B1 (en) | 1999-12-17 | 2003-10-14 | Joan M. Fallon | Methods for treating pervasive development disorders |
US20070053895A1 (en) | 2000-08-14 | 2007-03-08 | Fallon Joan M | Method of treating and diagnosing parkinsons disease and related dysautonomic disorders |
US6660831B2 (en) | 2000-08-14 | 2003-12-09 | Joan M. Fallon | Method for diagnosing and treating dysautonomia and other dysautonomic conditions |
US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
IL162604A0 (en) * | 2002-01-03 | 2005-11-20 | Yissum Res Dev Co | Conformationally constrained c-backbone cyclic peptides |
US20030144260A1 (en) * | 2002-01-03 | 2003-07-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Heterocyclic compounds, method of developing new drug leads and combinatorial libraries used in such method |
IL148921A0 (en) * | 2002-03-26 | 2002-09-12 | Peptor Ltd | Photo active backbone cyclized somatostatin analogs for optical imaging and photodynamic therapy |
US6987167B2 (en) * | 2002-05-22 | 2006-01-17 | Wockhardt Limited | Process for production of the somatostatin analog, octreotide |
IL150384A0 (en) * | 2002-06-24 | 2002-12-01 | Peptor Ltd | Radiolabelled somatostatin analogs backbone cyclized through metal complexation |
US20060211507A1 (en) * | 2005-03-21 | 2006-09-21 | Intertex, Inc. | Stake for securing inflatable devices |
AU2006253733A1 (en) * | 2005-05-31 | 2006-12-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Backbone cyclized melanocortin stimulating hormone (alpha S ) analogs |
US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
US8658163B2 (en) | 2008-03-13 | 2014-02-25 | Curemark Llc | Compositions and use thereof for treating symptoms of preeclampsia |
US8084025B2 (en) | 2008-04-18 | 2011-12-27 | Curemark Llc | Method for the treatment of the symptoms of drug and alcohol addiction |
US9320780B2 (en) | 2008-06-26 | 2016-04-26 | Curemark Llc | Methods and compositions for the treatment of symptoms of Williams Syndrome |
ES2732453T3 (es) | 2008-07-01 | 2019-11-22 | Curemark Llc | Métodos y composiciones para el tratamiento de síntomas de trastornos neurológicos y de salud mental |
US10776453B2 (en) | 2008-08-04 | 2020-09-15 | Galenagen, Llc | Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain |
US20100092447A1 (en) | 2008-10-03 | 2010-04-15 | Fallon Joan M | Methods and compositions for the treatment of symptoms of prion diseases |
AU2010203714C1 (en) | 2009-01-06 | 2013-12-12 | Galenagen, Llc | Compositions and methods for the treatment or the prevention of infections by e. coli |
CN105664144B (zh) | 2009-01-06 | 2020-08-11 | 加尔纳根有限责任公司 | 治疗或预防金黄色葡萄球菌感染以及根除或减少表面上金黄色葡萄球菌的组合物和方法 |
US9056050B2 (en) | 2009-04-13 | 2015-06-16 | Curemark Llc | Enzyme delivery systems and methods of preparation and use |
US9511125B2 (en) | 2009-10-21 | 2016-12-06 | Curemark Llc | Methods and compositions for the treatment of influenza |
AU2012245287B2 (en) | 2011-04-21 | 2017-04-13 | Curemark, Llc | Compounds for the treatment of neuropsychiatric disorders |
US10350278B2 (en) | 2012-05-30 | 2019-07-16 | Curemark, Llc | Methods of treating Celiac disease |
US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE150199C (es) * | ||||
FR2611722B1 (fr) * | 1987-03-02 | 1989-08-11 | Inst Nat Sante Rech Med | Nouveaux peptides derives de la cck8, leur preparation et les compositions pharmaceutiques qui les contiennent |
GB8807246D0 (en) * | 1988-03-25 | 1988-04-27 | Merck Sharp & Dohme | Therapeutic agents |
CA2036973A1 (en) * | 1990-02-27 | 1991-08-28 | Mark G. Bock | Cyclic hexapeptide oxytocin antagonists |
US5169935A (en) * | 1990-06-20 | 1992-12-08 | The Salk Institute For Biological Studies | Method of making peptides |
-
1991
- 1991-10-02 IL IL9962891A patent/IL99628A/en not_active IP Right Cessation
-
1992
- 1992-10-02 EP EP92309016A patent/EP0564739B1/en not_active Expired - Lifetime
- 1992-10-02 AT AT92309016T patent/ATE189228T1/de not_active IP Right Cessation
- 1992-10-02 JP JP30434792A patent/JP3509029B2/ja not_active Expired - Fee Related
- 1992-10-02 DE DE69230610T patent/DE69230610T2/de not_active Expired - Fee Related
-
1995
- 1995-05-18 US US08/444,135 patent/US5723575A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0564739A3 (es) | 1995-04-26 |
DE69230610T2 (de) | 2000-12-28 |
DE69230610D1 (de) | 2000-03-02 |
US5723575A (en) | 1998-03-03 |
JP3509029B2 (ja) | 2004-03-22 |
JPH06263797A (ja) | 1994-09-20 |
EP0564739A2 (en) | 1993-10-13 |
ATE189228T1 (de) | 2000-02-15 |
EP0564739B1 (en) | 2000-01-26 |
IL99628A0 (en) | 1992-08-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |