IL98757A - Piperidine derivatives their preparation and pharmaceutical compositions containing them - Google Patents
Piperidine derivatives their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL98757A IL98757A IL9875791A IL9875791A IL98757A IL 98757 A IL98757 A IL 98757A IL 9875791 A IL9875791 A IL 9875791A IL 9875791 A IL9875791 A IL 9875791A IL 98757 A IL98757 A IL 98757A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- preparation
- piperidine derivatives
- compositions containing
- piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK172490A DK172490D0 (da) | 1990-07-18 | 1990-07-18 | Ny heterocyklisk kemi |
| DK11791A DK11791D0 (da) | 1991-01-24 | 1991-01-24 | Ny heterocyklisk kemi |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL98757A0 IL98757A0 (en) | 1992-07-15 |
| IL98757A true IL98757A (en) | 1997-01-10 |
Family
ID=26063347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9875791A IL98757A (en) | 1990-07-18 | 1991-07-08 | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5328917A (no) |
| EP (1) | EP0558487B1 (no) |
| JP (1) | JPH06500076A (no) |
| CN (1) | CN1058207A (no) |
| AT (1) | ATE171943T1 (no) |
| AU (1) | AU661276B2 (no) |
| CA (1) | CA2087538A1 (no) |
| DE (1) | DE69130326D1 (no) |
| FI (1) | FI930171A0 (no) |
| IE (1) | IE912456A1 (no) |
| IL (1) | IL98757A (no) |
| NO (1) | NO179974C (no) |
| NZ (1) | NZ238990A (no) |
| PT (1) | PT98375B (no) |
| WO (1) | WO1992001672A1 (no) |
| ZW (1) | ZW9791A1 (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2150951A1 (en) * | 1992-12-14 | 1994-06-23 | Angus Murray Macleod | 4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperidines as tachykinin receptor antagonists |
| DE4302051A1 (de) * | 1993-01-26 | 1994-07-28 | Thomae Gmbh Dr K | 5-gliedrige Heterocyclen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| EP0639568A1 (en) * | 1993-08-19 | 1995-02-22 | Novo Nordisk A/S | Piperidine compounds, their preparation and use in the treatment of neurodegenerative disorders |
| GB9526645D0 (en) * | 1995-12-28 | 1996-02-28 | Chiroscience Ltd | Stereoselective synthesis |
| GB9623359D0 (en) * | 1996-11-09 | 1997-01-08 | Smithkline Beecham Plc | Novel process |
| AP9901698A0 (en) * | 1997-05-29 | 1999-12-31 | Smithkline Beecham Corp | Novel process. |
| GB9725541D0 (en) * | 1997-12-02 | 1998-02-04 | Pharmacia & Upjohn Spa | Amino-benzothiazole derivatives |
| GB9912411D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
| JP2004509103A (ja) | 2000-09-11 | 2004-03-25 | セプレイコー インコーポレイテッド | モノアミン受容体及び輸送体のリガンドならびにその使用方法 |
| US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
| US6727264B1 (en) | 2001-07-05 | 2004-04-27 | Synaptic Pharmaceutical Corporation | Substituted anilinic piperidines as MCH selective antagonists |
| WO2005032479A2 (en) | 2003-10-01 | 2005-04-14 | Unviversity Of Florida Research Foundation, Inc. | Compositions and methods for selective inhibition of nicotine acetylcholine receptors |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
| US7872022B2 (en) * | 2006-04-03 | 2011-01-18 | Hoffmann-La Roche Inc. | Serotonin transporter (SERT) inhibitors for the treatment of depression and anxiety |
| EP2085383A4 (en) | 2006-11-16 | 2010-09-22 | Astellas Pharma Inc | Piperidin derivatives or salts thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| DK149624C (da) * | 1983-03-07 | 1987-02-02 | Ferrosan As | Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne |
| EP0190496A3 (en) * | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Piperidine derivatives having a gastro-intestinal activity |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| US5017585A (en) * | 1986-11-03 | 1991-05-21 | Novo Nordisk A/S | Method of treating calcium overload |
| DK231088D0 (da) * | 1988-04-28 | 1988-04-28 | Ferrosan As | Piperidinforbindelser, deres fremstilling og anvendelse |
| DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
| DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
-
1991
- 1991-07-08 IL IL9875791A patent/IL98757A/xx not_active IP Right Cessation
- 1991-07-15 WO PCT/DK1991/000206 patent/WO1992001672A1/en active IP Right Grant
- 1991-07-15 CA CA002087538A patent/CA2087538A1/en not_active Abandoned
- 1991-07-15 EP EP91913359A patent/EP0558487B1/en not_active Expired - Lifetime
- 1991-07-15 AT AT91913359T patent/ATE171943T1/de not_active IP Right Cessation
- 1991-07-15 IE IE245691A patent/IE912456A1/en unknown
- 1991-07-15 JP JP3512512A patent/JPH06500076A/ja active Pending
- 1991-07-15 DE DE69130326T patent/DE69130326D1/de not_active Expired - Lifetime
- 1991-07-15 AU AU82241/91A patent/AU661276B2/en not_active Ceased
- 1991-07-16 NZ NZ238990A patent/NZ238990A/en unknown
- 1991-07-17 ZW ZW97/91A patent/ZW9791A1/xx unknown
- 1991-07-18 PT PT98375A patent/PT98375B/pt not_active IP Right Cessation
- 1991-07-18 CN CN91104954A patent/CN1058207A/zh active Pending
-
1993
- 1993-01-15 NO NO930143A patent/NO179974C/no unknown
- 1993-01-15 FI FI930171A patent/FI930171A0/fi not_active Application Discontinuation
- 1993-05-20 US US08/065,513 patent/US5328917A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL98757A0 (en) | 1992-07-15 |
| AU8224191A (en) | 1992-02-18 |
| PT98375A (pt) | 1992-05-29 |
| ZW9791A1 (en) | 1991-10-09 |
| FI930171A (fi) | 1993-01-15 |
| WO1992001672A1 (en) | 1992-02-06 |
| IE912456A1 (en) | 1992-01-29 |
| DE69130326D1 (de) | 1998-11-12 |
| FI930171A0 (fi) | 1993-01-15 |
| NZ238990A (en) | 1994-06-27 |
| EP0558487B1 (en) | 1998-10-07 |
| NO930143D0 (no) | 1993-01-15 |
| NO930143L (no) | 1993-01-18 |
| NO179974C (no) | 1997-01-22 |
| AU661276B2 (en) | 1995-07-20 |
| EP0558487A1 (en) | 1993-09-08 |
| CA2087538A1 (en) | 1992-01-19 |
| ATE171943T1 (de) | 1998-10-15 |
| PT98375B (pt) | 1999-01-29 |
| CN1058207A (zh) | 1992-01-29 |
| NO179974B (no) | 1996-10-14 |
| JPH06500076A (ja) | 1994-01-06 |
| US5328917A (en) | 1994-07-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW221811B (no) | ||
| IL108087A (en) | 2-substituted-3-azaindolyl- acrylonitrile and 3-(azaindolyl-methylene) oxindole derivatives, process for their preparation and pharmaceutical compositions containing them | |
| AP9801378A0 (en) | 9-amino-3- keto erythromycin derivatives. | |
| CA2258548A1 (en) | Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases | |
| IL98757A0 (en) | Piperidine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL110494A0 (en) | Perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them | |
| NZ240230A (en) | Mercaptoacetylamide derivatives; preparation, use and pharmaceutical compositions thereof | |
| IL94433A0 (en) | Aminophenol derivatives,their preparation and pharmaceutical compositions containing them | |
| IL111077A (en) | Pyridine derivatives processes for the preparation thereof and pharmaceutical compositions containing them | |
| BG103947A (en) | Derivatives of 9-oxymerythromycin | |
| IL102759A0 (en) | Hydantoin derivatives,their preparation and pharmaceutical compositions containing them | |
| GR1001597B (el) | Νέα βιολογικώς δραστικά παράγωγα εμπουρναμενίνης, φαρμακευτικές συν?έσεις οι οποίες περιέχουν αυτά και μέ?οδος δια την παρασκευή αυτών. | |
| AP9801377A0 (en) | Tricyclic erythromycin derivatives. | |
| IL110460A0 (en) | Bis-naphthalimides and pharmaceutical compositions containing them | |
| ZA93494B (en) | Napthalene amides and sulphonamides, processes for their preparation and pharmaceutical compositions containing them | |
| ES2019840A6 (es) | Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina. | |
| TW252979B (no) | ||
| GR3023757T3 (en) | Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents. | |
| AP9801235A0 (en) | Erythromycin derivatives. | |
| ZA955052B (en) | Pyrrolidine derivatives their preparation and compositions containing them | |
| MX9703610A (es) | Nuevas (5,6)-heteroaril condensado-pirimidin-4-onas 2,3 disustituidas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |