IL98354A0 - Method for preparing interferon alpha-2 crystals - Google Patents

Method for preparing interferon alpha-2 crystals

Info

Publication number
IL98354A0
IL98354A0 IL98354A IL9835491A IL98354A0 IL 98354 A0 IL98354 A0 IL 98354A0 IL 98354 A IL98354 A IL 98354A IL 9835491 A IL9835491 A IL 9835491A IL 98354 A0 IL98354 A0 IL 98354A0
Authority
IL
Israel
Prior art keywords
crystals
interferon alpha
preparing interferon
preparing
zinc
Prior art date
Application number
IL98354A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL98354A0 publication Critical patent/IL98354A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL98354A 1990-06-04 1991-06-03 Method for preparing interferon alpha-2 crystals IL98354A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53322590A 1990-06-04 1990-06-04

Publications (1)

Publication Number Publication Date
IL98354A0 true IL98354A0 (en) 1992-07-15

Family

ID=24125036

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98354A IL98354A0 (en) 1990-06-04 1991-06-03 Method for preparing interferon alpha-2 crystals

Country Status (24)

Country Link
US (2) US5460956A (xx)
EP (1) EP0597851B1 (xx)
JP (1) JPH0749440B2 (xx)
CN (2) CN1033035C (xx)
AT (1) ATE149523T1 (xx)
AU (1) AU636043B2 (xx)
CA (1) CA2084406A1 (xx)
DE (1) DE69125035T2 (xx)
ES (1) ES2098358T3 (xx)
FI (1) FI925515A (xx)
HU (1) HUT63185A (xx)
IE (1) IE911892A1 (xx)
IL (1) IL98354A0 (xx)
MX (1) MX9203319A (xx)
MY (1) MY107450A (xx)
NO (1) NO924672D0 (xx)
NZ (1) NZ238384A (xx)
OA (1) OA09720A (xx)
PL (1) PL166045B1 (xx)
PT (1) PT97849A (xx)
SG (1) SG45207A1 (xx)
TW (1) TW342395B (xx)
WO (1) WO1991018927A1 (xx)
ZA (1) ZA914200B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912015A (en) * 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US5711968A (en) 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
SE9302278D0 (sv) * 1992-10-28 1993-07-02 Kabi Pharmacia Ab Growth hormone
US5441734A (en) * 1993-02-25 1995-08-15 Schering Corporation Metal-interferon-alpha crystals
AU706180B2 (en) * 1994-07-25 1999-06-10 Alkermes Controlled Therapeutics, Inc. Controlled release of metal cation-stabilized interferon
AU710347B2 (en) * 1995-08-31 1999-09-16 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
US5972331A (en) * 1995-12-22 1999-10-26 Schering Corporation Crystalline interferon alpha for pulmonary delivery and method for producing the same
US6392069B2 (en) 1996-01-08 2002-05-21 Canji, Inc. Compositions for enhancing delivery of nucleic acids to cells
US20100251425A9 (en) * 1998-05-15 2010-09-30 University Of Central Florida Expression of human interferon in transgenic chloroplasts
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
DE19859876A1 (de) 1998-12-23 2000-06-29 Fraunhofer Ges Forschung Verfahren zur Kristallisation aus Lösungen
US6465425B1 (en) 2000-02-10 2002-10-15 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
EP1441727B1 (en) * 2001-10-30 2010-12-29 Novartis AG Depot formulations of iloperidone and a star polymer
GB0216416D0 (en) * 2002-07-15 2002-08-21 Novartis Ag Organic compounds
DE60332358D1 (de) * 2002-09-09 2010-06-10 Hanall Pharmaceutical Co Ltd Protease-resistente modifizierte interferon alpha polypeptide
CA2512052C (en) 2002-12-31 2016-06-21 Altus Pharmaceuticals Inc. Human growth hormone crystals and methods for preparing them
KR20050094832A (ko) * 2002-12-31 2005-09-28 알투스 파마슈티컬스 인코포레이티드 단백질 결정과 이온성 중합체를 함유하는 복합체
US8778880B2 (en) 2004-02-02 2014-07-15 Ambrx, Inc. Human growth hormone modified at position 35
US8679472B1 (en) 2006-10-05 2014-03-25 Merck, Sharp & Dohme Corp. Crystal of human interferon alpha 2B in complex with zinc
MX2010008632A (es) 2008-02-08 2010-08-30 Ambrx Inc Leptina-polipeptidos modificados y sus usos.
US20110027229A1 (en) 2009-07-31 2011-02-03 Medtronic, Inc. Continuous subcutaneous administration of interferon-alpha to hepatitis c infected patients
WO2015088990A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2882203A (en) * 1951-06-26 1959-04-14 Novo Terapeutisk Labor As Injectable insulin preparation with protracted effect
US2822203A (en) * 1955-02-17 1958-02-04 Gen Motors Corp Door latch and control means
US4315852A (en) * 1980-11-26 1982-02-16 Schering Corporation Extraction of interferon from bacteria
US4672108A (en) * 1981-12-07 1987-06-09 Hoffmann-La Roche Inc. Crystalline human leukocyte interferon
US4853218A (en) * 1987-02-24 1989-08-01 Schering Corporation Zinc-protamine-alpha interferon complex
US5441734A (en) * 1993-02-25 1995-08-15 Schering Corporation Metal-interferon-alpha crystals

Also Published As

Publication number Publication date
CN1044709C (zh) 1999-08-18
SG45207A1 (en) 1998-01-16
PL166045B1 (pl) 1995-03-31
US5460956A (en) 1995-10-24
JPH05503292A (ja) 1993-06-03
AU7955291A (en) 1991-12-31
TW342395B (en) 1998-10-11
IE911892A1 (en) 1991-12-04
ZA914200B (en) 1992-03-25
ES2098358T3 (es) 1997-05-01
EP0597851A1 (en) 1994-05-25
CN1132212A (zh) 1996-10-02
ATE149523T1 (de) 1997-03-15
US5741485A (en) 1998-04-21
MX9203319A (es) 1992-07-31
PT97849A (pt) 1992-03-31
CN1033035C (zh) 1996-10-16
DE69125035T2 (de) 1997-07-10
WO1991018927A1 (en) 1991-12-12
CN1058022A (zh) 1992-01-22
MY107450A (en) 1995-12-30
NZ238384A (en) 1992-11-25
FI925515A0 (fi) 1992-12-04
HUT63185A (en) 1993-07-28
OA09720A (en) 1993-08-30
NO924672L (no) 1992-12-03
JPH0749440B2 (ja) 1995-05-31
NO924672D0 (no) 1992-12-03
AU636043B2 (en) 1993-04-08
EP0597851B1 (en) 1997-03-05
FI925515A (fi) 1992-12-04
HU9203828D0 (en) 1993-03-29
CA2084406A1 (en) 1991-12-05
DE69125035D1 (de) 1997-04-10

Similar Documents

Publication Publication Date Title
ZA914200B (en) Method for preparing interferon alpha-2 crystals
EP0288316A3 (en) Compositionally modulated, nitrided alloy films and method for making the same
HK14094A (en) Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same
AU8071391A (en) Method, system and mold assembly for use in preparing a dental restoration
ZA928993B (en) Process for preparing sintered shapes and compositions used therein.
EP0445738A3 (en) Perfluoropolyethers and processes for preparing them
AU7644391A (en) Powdered leather and method of producing the same
EP0439755A3 (en) Process for preparing graft polyols and the polyols prepared thereby
MY106109A (en) 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions
ZA929001B (en) Process for preparing sintered shapes and compositions for use therein.
GB2163750B (en) Method for producing human leukocyte interferon alpha-2
AU7252391A (en) Device for subcutaneous introduction, in particular for the implantation of artificial hairs
EP0637915A4 (en) COMPOSITIONS AND METHODS FOR REGULATING THE PRODUCTION OF INTERLEUKIN-6 IN VIVO.
AU658314B2 (en) Growth promotion in swine
GR3037000T3 (en) One-pot process for preparing pergolide.
IL91392A0 (en) Method of increasing the ovulation rate in swine
CS390590A3 (en) Substituted 5,15-diphenylporphyrins and process for preparing thereof
AU2018595A (en) Intermediates useful in preparing piperidin-4-spiro-oxiranes
HU902516D0 (en) Cosmetical composition, primarily for coitus suspectus, and process for the production thereof
EP0462452B1 (de) Polycyanopyrimidine und Verfahren zu ihrer Herstellung.
DE3163650D1 (en) Peptide, a process for producing the heptacosapeptide and the use of the heptacosapeptide for producing secretin
AU9047091A (en) Immunotherapeutic agents, compositions and methods
YU270280A (en) Process for preparing (trimethoxy-3,'4,'5,')-cinnamoyl-1-piperazine and chlorohydrate thereof
SG3294G (en) Pharmacologically active 1, 5-diaryl-3-substituted-pyrazoles and method for synthesizing the same
ZA873842B (en) Pharmacologically active 1,5-diarly-3-substituted-pyrazoles and method for synthesizing the same