IL98090A - Dihydrobenzofiran-2-carboxylic acids converted by alkoxy and their history and pharmaceutical preparations containing them - Google Patents
Dihydrobenzofiran-2-carboxylic acids converted by alkoxy and their history and pharmaceutical preparations containing themInfo
- Publication number
- IL98090A IL98090A IL9809091A IL9809091A IL98090A IL 98090 A IL98090 A IL 98090A IL 9809091 A IL9809091 A IL 9809091A IL 9809091 A IL9809091 A IL 9809091A IL 98090 A IL98090 A IL 98090A
- Authority
- IL
- Israel
- Prior art keywords
- propyl
- carbon atoms
- compound
- dihydro
- benzopyran
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/521,777 US5073562A (en) | 1990-05-10 | 1990-05-10 | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL98090A0 IL98090A0 (en) | 1992-06-21 |
| IL98090A true IL98090A (en) | 1995-07-31 |
Family
ID=24078110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9809091A IL98090A (en) | 1990-05-10 | 1991-05-09 | Dihydrobenzofiran-2-carboxylic acids converted by alkoxy and their history and pharmaceutical preparations containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5073562A (fr) |
| EP (1) | EP0527922B1 (fr) |
| JP (1) | JPH05507084A (fr) |
| AT (1) | ATE119528T1 (fr) |
| AU (1) | AU647487B2 (fr) |
| CA (1) | CA2082500A1 (fr) |
| DE (1) | DE69108025T2 (fr) |
| DK (1) | DK0527922T3 (fr) |
| ES (1) | ES2069295T3 (fr) |
| GR (1) | GR3015349T3 (fr) |
| IE (1) | IE62719B1 (fr) |
| IL (1) | IL98090A (fr) |
| NZ (1) | NZ238092A (fr) |
| PT (1) | PT97614A (fr) |
| WO (1) | WO1991017160A1 (fr) |
| ZA (1) | ZA913546B (fr) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677021B1 (fr) * | 1991-05-31 | 1993-10-01 | Upsa Laboratoires | Nouveaux derives de thiazole antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| US5352690A (en) * | 1992-07-01 | 1994-10-04 | Eli Lilly And Company | 1,2,4-trioxygenated benzene derivatives useful as leukotriene antagonists |
| AU2585595A (en) * | 1994-05-25 | 1995-12-18 | G.D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-sulfonimides derivatives, their preparation and their use as leukotriene b4 antagonists |
| US5516917A (en) * | 1994-06-08 | 1996-05-14 | G. D. Searle & Co. | Leukotriene B4 antagonists |
| AU696890B2 (en) * | 1994-10-13 | 1998-09-24 | Pfizer Inc. | Benzopyran and benzo-fused compounds, their preparation and their use as leukotriene B4 (LTB4) antagonists |
| CA2202056A1 (fr) * | 1994-10-13 | 1996-04-25 | Mark A. Dombroski | Composes de benzopyranne et composes benzo-fusionnes, leur preparation et leur utilisation comme antagonistes du leucotriene b4' (ltb4) |
| AU1707700A (en) * | 1998-10-29 | 2000-05-22 | Bristol-Myers Squibb Company | Novel inhibitors of impdh enzyme |
| PE20020453A1 (es) | 2000-09-27 | 2002-06-06 | Merck & Co Inc | Derivados del acido benzopirancarboxilico para el tratamiento de la diabetes y los trastornos de lipidos |
| EP1347755A2 (fr) * | 2000-10-31 | 2003-10-01 | Merck & Co., Inc. | Derives d'acide benzopyranocarboxylique pour traiter le diabete et d'autres troubles lipidiques |
| US7446127B2 (en) * | 2003-08-27 | 2008-11-04 | Sk Holdings Co, Ltd. | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| EP3492602A1 (fr) | 2005-06-15 | 2019-06-05 | Complete Genomics, Inc. | Réseaux de molécules simples pour l'analyse génétique et chimique |
| EP1951900B1 (fr) | 2005-10-07 | 2016-06-15 | Callida Genomics, Inc. | Biopuces à molécules simples autoassemblées et utilisations |
| CA2643700A1 (fr) | 2006-02-24 | 2007-11-22 | Callida Genomics, Inc. | Sequencage genomique a haut debit sur des puces a adn |
| EP2766498B1 (fr) | 2011-10-14 | 2019-06-19 | President and Fellows of Harvard College | Séquençage par assemblage structurel |
| WO2013184754A2 (fr) | 2012-06-05 | 2013-12-12 | President And Fellows Of Harvard College | Séquençage spatial d'acides nucléiques à l'aide de sondes d'origami d'adn |
| US9476089B2 (en) | 2012-10-18 | 2016-10-25 | President And Fellows Of Harvard College | Methods of making oligonucleotide probes |
| US9540685B2 (en) | 2013-03-15 | 2017-01-10 | President And Fellows Of Harvard College | Methods of identifying homologous genes using FISH |
| CN107075546B (zh) | 2014-08-19 | 2021-08-31 | 哈佛学院董事及会员团体 | 用于对核酸探测并作图的rna-引导的系统 |
| US20230109070A1 (en) | 2019-10-18 | 2023-04-06 | The Board of Trustees og the Leland Standford Junior University | Clinical- and industrial-scale intact-tissue sequencing |
| US20220228200A1 (en) | 2021-01-19 | 2022-07-21 | 10X Genomics, Inc. | Methods and compositions for internally controlled in situ assays |
| CN117396613A (zh) | 2021-06-01 | 2024-01-12 | 10X基因组学有限公司 | 用于分析物检测和探针解析的方法和组合物 |
| EP4347880A1 (fr) | 2021-06-02 | 2024-04-10 | 10X Genomics, Inc. | Analyse d'échantillon à l'aide de sondes circularisables asymétriques |
| CN117651855A (zh) | 2021-07-13 | 2024-03-05 | 10X基因组学有限公司 | 用于制备具有可控厚度的聚合基质的方法 |
| WO2023015192A1 (fr) | 2021-08-03 | 2023-02-09 | 10X Genomics, Inc. | Concatémères d'acide nucléique et procédés de stabilisation et/ou de compactage de ceux-ci |
| US20230061542A1 (en) | 2021-08-16 | 2023-03-02 | 10X Genomics, Inc. | Probes comprising a split barcode region and methods of use |
| US20230242974A1 (en) | 2021-12-27 | 2023-08-03 | 10X Genomics, Inc. | Methods and compositions for rolling circle amplification |
| US20230279475A1 (en) | 2022-01-21 | 2023-09-07 | 10X Genomics, Inc. | Multiple readout signals for analyzing a sample |
| WO2023164570A1 (fr) | 2022-02-23 | 2023-08-31 | Insitro, Inc. | Criblage optique groupé et mesures transcriptionnelles de cellules comprenant des perturbations génétiques à code-barres |
| WO2023215603A1 (fr) | 2022-05-06 | 2023-11-09 | 10X Genomics, Inc. | Procédés et compositions pour l'analyse in situ de séquences v(d)j |
| WO2023245190A1 (fr) | 2022-06-17 | 2023-12-21 | 10X Genomics, Inc. | DÉ-RÉTICULATION CATALYTIQUE D'ÉCHANTILLONS POUR ANALYSE IN SITU <i /> |
| US20240191297A1 (en) | 2022-10-14 | 2024-06-13 | 10X Genomics, Inc. | Methods, compositions, and systems for assessing biological sample quality |
| WO2024102736A1 (fr) | 2022-11-08 | 2024-05-16 | 10X Genomics, Inc. | Procédés et compositions d'immobilisation pour détection in situ |
| US20240158852A1 (en) | 2022-11-16 | 2024-05-16 | 10X Genomics, Inc. | Methods and compositions for assessing performance of in situ assays |
| WO2024130203A1 (fr) | 2022-12-16 | 2024-06-20 | 10X Genomics, Inc. | Procédés et compositions d'évaluation de performances |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| EP0017332B1 (fr) * | 1979-03-20 | 1985-07-31 | FISONS plc | Composés hétérocycliques à activité pharmaceutique, procédés pour leur préparation et compositions les contenant |
| US4474788A (en) * | 1981-11-12 | 1984-10-02 | Fisons Plc | Anti-SRSA quinoline carboxylic acid derivatives |
| US4788214A (en) * | 1983-06-24 | 1988-11-29 | Hoffman-La Roche Inc. | 3,4-dihydro-2H-1-benzopyran derivatives |
| ZA844519B (en) * | 1983-06-24 | 1985-02-27 | Hoffmann La Roche | Dihydrobenzopyran derivatives |
| US4665203A (en) * | 1983-08-08 | 1987-05-12 | G. D. Searle & Co. | Substituted dihydrobenzopyrans useful as leukotriene D4 inhibitors |
| US4778903A (en) * | 1983-12-12 | 1988-10-18 | G. D. Searle & Co. | Substituted dihydrobenzopyrans |
| ZA84345B (en) * | 1983-08-08 | 1985-02-27 | Searle & Co | Substituted dihydrobenzopyrans |
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US4546194A (en) * | 1984-05-29 | 1985-10-08 | G. D. Searle & Co. | Substituted chromanon-2-yl alkanols and derivatives thereof |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| MX13485A (es) * | 1987-10-19 | 1993-05-01 | Pfizer | Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos |
-
1990
- 1990-05-10 US US07/521,777 patent/US5073562A/en not_active Expired - Fee Related
-
1991
- 1991-05-01 ES ES91910026T patent/ES2069295T3/es not_active Expired - Lifetime
- 1991-05-01 AU AU79020/91A patent/AU647487B2/en not_active Ceased
- 1991-05-01 DE DE69108025T patent/DE69108025T2/de not_active Expired - Fee Related
- 1991-05-01 EP EP91910026A patent/EP0527922B1/fr not_active Expired - Lifetime
- 1991-05-01 CA CA002082500A patent/CA2082500A1/fr not_active Abandoned
- 1991-05-01 DK DK91910026.3T patent/DK0527922T3/da active
- 1991-05-01 AT AT91910026T patent/ATE119528T1/de not_active IP Right Cessation
- 1991-05-01 JP JP91509388A patent/JPH05507084A/ja active Pending
- 1991-05-01 WO PCT/US1991/002981 patent/WO1991017160A1/fr active IP Right Grant
- 1991-05-09 PT PT97614A patent/PT97614A/pt not_active Application Discontinuation
- 1991-05-09 IL IL9809091A patent/IL98090A/en not_active IP Right Cessation
- 1991-05-09 NZ NZ238092A patent/NZ238092A/xx unknown
- 1991-05-09 IE IE158391A patent/IE62719B1/en not_active IP Right Cessation
- 1991-05-10 ZA ZA913546A patent/ZA913546B/xx unknown
-
1995
- 1995-03-09 GR GR950400438T patent/GR3015349T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU647487B2 (en) | 1994-03-24 |
| IL98090A0 (en) | 1992-06-21 |
| DK0527922T3 (da) | 1995-05-22 |
| EP0527922B1 (fr) | 1995-03-08 |
| CA2082500A1 (fr) | 1991-11-11 |
| DE69108025D1 (de) | 1995-04-13 |
| ES2069295T3 (es) | 1995-05-01 |
| IE62719B1 (en) | 1995-02-22 |
| WO1991017160A1 (fr) | 1991-11-14 |
| ATE119528T1 (de) | 1995-03-15 |
| US5073562A (en) | 1991-12-17 |
| NZ238092A (en) | 1993-10-26 |
| AU7902091A (en) | 1991-11-27 |
| IE911583A1 (en) | 1991-11-20 |
| EP0527922A1 (fr) | 1993-02-24 |
| ZA913546B (en) | 1992-07-29 |
| DE69108025T2 (de) | 1995-08-10 |
| GR3015349T3 (en) | 1995-06-30 |
| PT97614A (pt) | 1992-01-31 |
| JPH05507084A (ja) | 1993-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU647487B2 (en) | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof | |
| EP0593478B1 (fr) | Antagonistes de leukotriene b 4 | |
| EP0605729B1 (fr) | Derive d'oxazolidine et son sel pharmaceutiquement acceptable | |
| JP4276074B2 (ja) | ペルオキシソーム増殖剤応答性受容体δの活性化剤 | |
| EP0243018B1 (fr) | Dérivés d'acide thiolactame-N-acétique, leur préparation et leur application | |
| EP0456835A1 (fr) | Derive de l'acide quinazoline-3-alcanoique, sels derives de ce compose et sa production | |
| KR20000016412A (ko) | 신규한 치환 2,4-티아졸리디네디온 유도체, 이의제조 방법 및이를 함유하는 약제학적 조성물 | |
| US4746669A (en) | Substituted thiazoles as immunoregulants | |
| EP0528935B1 (fr) | Acides dihydrobenzopyran-2-carboxyliques a substitution alcoxy et leurs derives | |
| US5516917A (en) | Leukotriene B4 antagonists | |
| US5192782A (en) | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof | |
| US5212198A (en) | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof | |
| US5578619A (en) | Alkoxy-substituted dihydrobenzopyran-2-sulfonimides | |
| US5380740A (en) | Anti-inflammatory compounds, compositions and method of use thereof | |
| JPH04270273A (ja) | チアゾリジン−２，４−ジオン誘導体とその塩及びその製造法 | |
| US4855426A (en) | Process of preparing 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins | |
| US4761413A (en) | 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins and use in treatment of ulcers | |
| IE914409A1 (en) | Anti-inflammatory compounds | |
| US4910198A (en) | 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |