IL97677A - Method for recovering fetal cells from a blood sample containing a mixed population of maternal and fetal cells - Google Patents

Method for recovering fetal cells from a blood sample containing a mixed population of maternal and fetal cells

Info

Publication number
IL97677A
IL97677A IL9767791A IL9767791A IL97677A IL 97677 A IL97677 A IL 97677A IL 9767791 A IL9767791 A IL 9767791A IL 9767791 A IL9767791 A IL 9767791A IL 97677 A IL97677 A IL 97677A
Authority
IL
Israel
Prior art keywords
cells
antibody
maternal
fetal
labeled
Prior art date
Application number
IL9767791A
Other languages
English (en)
Other versions
IL97677A0 (en
Original Assignee
Genetype Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetype Ag filed Critical Genetype Ag
Publication of IL97677A0 publication Critical patent/IL97677A0/xx
Publication of IL97677A publication Critical patent/IL97677A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/824Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
IL9767791A 1990-03-27 1991-03-26 Method for recovering fetal cells from a blood sample containing a mixed population of maternal and fetal cells IL97677A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/499,932 US5153117A (en) 1990-03-27 1990-03-27 Fetal cell recovery method

Publications (2)

Publication Number Publication Date
IL97677A0 IL97677A0 (en) 1992-06-21
IL97677A true IL97677A (en) 1996-07-23

Family

ID=23987348

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9767791A IL97677A (en) 1990-03-27 1991-03-26 Method for recovering fetal cells from a blood sample containing a mixed population of maternal and fetal cells

Country Status (16)

Country Link
US (2) US5153117A (fr)
EP (1) EP0521909B1 (fr)
JP (1) JP2965699B2 (fr)
AT (1) ATE194166T1 (fr)
AU (1) AU649027B2 (fr)
CA (1) CA2059554C (fr)
DE (1) DE69132269T2 (fr)
DK (1) DK0521909T3 (fr)
ES (1) ES2149760T3 (fr)
GR (1) GR3034487T3 (fr)
IE (1) IE910996A1 (fr)
IL (1) IL97677A (fr)
NZ (1) NZ237589A (fr)
SG (1) SG79188A1 (fr)
WO (1) WO1991014768A1 (fr)
ZA (1) ZA912317B (fr)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
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AU658132B2 (en) * 1989-11-13 1995-04-06 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
US5627029A (en) * 1991-05-03 1997-05-06 Genzyme Corporation Method for obtaining informative cells
EP0635067A1 (fr) * 1992-04-09 1995-01-25 Ig Laboratories Inc. Sondes pour detecter les aneuplo dies chromosomiques courantes d'enfants nes vivants
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
JPH07509136A (ja) * 1992-07-17 1995-10-12 バイシス,インク. インサイチュ(in situ)・ハイブリダイゼーションのための母体血液中の胎児細胞の富化と同定
US5275933A (en) * 1992-09-25 1994-01-04 The Board Of Trustees Of The Leland Stanford Junior University Triple gradient process for recovering nucleated fetal cells from maternal blood
CA2153257A1 (fr) * 1993-01-06 1994-07-21 Terry J. Fetterhoff Detection par fluorescence de cellules non viables
US5457024A (en) * 1993-01-22 1995-10-10 Aprogenex, Inc. Isolation of fetal erythrocytes
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US6890755B1 (en) * 1997-12-08 2005-05-10 The Trustees Of Columbia University In The City Of New York Recovery of fetal cells from maternal blood using chaotic advection
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US6210889B1 (en) * 1998-01-28 2001-04-03 The Universite Laval Method for enrichment of fetal cells from maternal blood and use of same in determination of fetal sex and detection of chromosomal abnormalities
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US4835098A (en) * 1985-09-04 1989-05-30 Regents Of University Of Minnesota Characterization of HLA alleles with locus-specific DNA probes
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US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method

Also Published As

Publication number Publication date
CA2059554A1 (fr) 1991-09-28
EP0521909A4 (en) 1993-11-18
CA2059554C (fr) 2004-06-22
DK0521909T3 (da) 2000-10-30
IE910996A1 (en) 1991-10-09
WO1991014768A1 (fr) 1991-10-03
ATE194166T1 (de) 2000-07-15
JPH05506144A (ja) 1993-09-16
AU649027B2 (en) 1994-05-12
EP0521909B1 (fr) 2000-06-28
ES2149760T3 (es) 2000-11-16
ZA912317B (en) 1991-12-24
JP2965699B2 (ja) 1999-10-18
DE69132269D1 (de) 2000-08-03
EP0521909A1 (fr) 1993-01-13
IL97677A0 (en) 1992-06-21
AU7471691A (en) 1991-10-21
US5153117A (en) 1992-10-06
NZ237589A (en) 1992-04-28
SG79188A1 (en) 2001-03-20
GR3034487T3 (en) 2000-12-29
DE69132269T2 (de) 2001-03-15
US5447842A (en) 1995-09-05

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