IL95880A - השימוש בתולדות 3-מותמרות של-2- אוקסינדול להכנת תכשירי רוקחות לעיכוב ביוסינטזה של אינטרלאוקיו-1 - Google Patents

השימוש בתולדות 3-מותמרות של-2- אוקסינדול להכנת תכשירי רוקחות לעיכוב ביוסינטזה של אינטרלאוקיו-1

Info

Publication number
IL95880A
IL95880A IL9588090A IL9588090A IL95880A IL 95880 A IL95880 A IL 95880A IL 9588090 A IL9588090 A IL 9588090A IL 9588090 A IL9588090 A IL 9588090A IL 95880 A IL95880 A IL 95880A
Authority
IL
Israel
Prior art keywords
pharmaceutically
compound
acceptable base
base salt
mammal
Prior art date
Application number
IL9588090A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL95880A publication Critical patent/IL95880A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL9588090A 1989-10-13 1990-10-02 השימוש בתולדות 3-מותמרות של-2- אוקסינדול להכנת תכשירי רוקחות לעיכוב ביוסינטזה של אינטרלאוקיו-1 IL95880A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42144589A 1989-10-13 1989-10-13
US52905090A 1990-05-25 1990-05-25

Publications (1)

Publication Number Publication Date
IL95880A true IL95880A (he) 1995-12-31

Family

ID=27025248

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9588090A IL95880A (he) 1989-10-13 1990-10-02 השימוש בתולדות 3-מותמרות של-2- אוקסינדול להכנת תכשירי רוקחות לעיכוב ביוסינטזה של אינטרלאוקיו-1

Country Status (14)

Country Link
US (1) US5192790A (he)
EP (1) EP0425109B1 (he)
JP (1) JPH0684300B2 (he)
KR (1) KR910007526A (he)
AT (1) ATE109349T1 (he)
AU (1) AU624739B2 (he)
CA (1) CA2027394C (he)
DE (1) DE69011272T2 (he)
DK (1) DK0425109T3 (he)
HU (2) HUT59004A (he)
IE (1) IE63140B1 (he)
IL (1) IL95880A (he)
MY (1) MY106834A (he)
PT (1) PT95566B (he)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6266485B1 (en) 1998-02-19 2001-07-24 Emerson Electric Co. One-piece plastic tank and temperature control system for a hot water dispenser
JP2002525362A (ja) * 1998-09-30 2002-08-13 エスヴァイン、アンゲリカ 代謝性骨障害の治療および予防のためのロダニンカルボン酸誘導体
US20020077276A1 (en) * 1999-04-27 2002-06-20 Fredeking Terry M. Compositions and methods for treating hemorrhagic virus infections and other disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
IN162090B (he) * 1984-03-19 1988-03-26 Pfizer
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
IN161509B (he) * 1984-05-04 1987-12-19 Pfizer
US4678802A (en) * 1985-07-09 1987-07-07 Pfizer Inc. 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
GB8517958D0 (en) * 1985-07-16 1985-08-21 Cellena Cell Eng Ag Compositions containing melatonin/homologues
AU6898287A (en) * 1986-01-30 1987-08-25 University Of Utah, The Treatment of bone loss
US4677132A (en) * 1986-03-12 1987-06-30 American Home Products Corporation Inhibition of bone resorption by etodolac
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives

Also Published As

Publication number Publication date
HU210902A9 (en) 1995-09-28
EP0425109B1 (en) 1994-08-03
IE903648A1 (en) 1991-04-24
PT95566B (pt) 1997-11-28
AU624739B2 (en) 1992-06-18
CA2027394A1 (en) 1991-04-14
DE69011272D1 (de) 1994-09-08
AU6458290A (en) 1991-04-18
DK0425109T3 (da) 1994-11-21
EP0425109A3 (en) 1992-01-15
ATE109349T1 (de) 1994-08-15
HU906436D0 (en) 1991-04-29
MY106834A (en) 1995-07-31
KR910007526A (ko) 1991-05-30
CA2027394C (en) 1995-01-03
JPH03133929A (ja) 1991-06-07
EP0425109A2 (en) 1991-05-02
HUT59004A (en) 1992-04-28
IE63140B1 (en) 1995-03-22
PT95566A (pt) 1991-08-14
US5192790A (en) 1993-03-09
JPH0684300B2 (ja) 1994-10-26
DE69011272T2 (de) 1994-11-24

Similar Documents

Publication Publication Date Title
EP1259239B1 (en) USE OF 2-(4-ETHOXY-PHENYL)-3-(4-METHANESULFONYL-PHENYL)-PYRAZOLO[1,5-b]PYRIDAZINE FOR THE TREATMENT OF NON-ULCERATIVE DYSPEPSIA
US7790738B2 (en) Methods of treating and preventing AIDS using of COX-2 inhibitors
CA2440744C (en) Il-12 expression controlling agent
US4861794A (en) 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
JP3306830B2 (ja) レトロウイルスインテグラーゼの阻害剤
KR20020075797A (ko) 엔도텔린 유발성 질환 치료제
US4853409A (en) 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
EP0425109B1 (en) 3-Substituted-2-oxindole derivatives as inhibitors of interleukin-1 biosynthesis
JPH10511978A (ja) アルツハイマー病の治療用薬剤
AU605702B2 (en) Derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines as inhibitors of interleukin-1 production
NZ237451A (en) The use of 5-chloro-2,3-dihydro-2-oxo-3-(2-thienylcarbonyl)indole-1-carboxamide in the preparation of a pharmaceutical composition
WO1992003130A1 (en) Use of aryl hydroxyurea compounds for the treatment of atherosclerosis
US20040053968A1 (en) Methods and compositions for treating peridontal disease
NZ235638A (en) The use of indole derivatives for treating interleukin-1 related disorders
US5071852A (en) Derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines as inhibitors of interleukin-1 production
CA2156120A1 (en) 3-substituted-2-oxindoles as inhibitors of viral replication

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void