IL95391A - N-) Quinoline-2-Il-Methoxy (benzyl-sulfonylureas, their preparation and pharmaceutical preparations containing them - Google Patents

N-) Quinoline-2-Il-Methoxy (benzyl-sulfonylureas, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL95391A
IL95391A IL9539190A IL9539190A IL95391A IL 95391 A IL95391 A IL 95391A IL 9539190 A IL9539190 A IL 9539190A IL 9539190 A IL9539190 A IL 9539190A IL 95391 A IL95391 A IL 95391A
Authority
IL
Israel
Prior art keywords
carbon atoms
chain
straight
branched alkyl
optionally substituted
Prior art date
Application number
IL9539190A
Other languages
English (en)
Hebrew (he)
Other versions
IL95391A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL95391A0 publication Critical patent/IL95391A0/xx
Publication of IL95391A publication Critical patent/IL95391A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Quinoline Compounds (AREA)
IL9539190A 1989-08-19 1990-08-16 N-) Quinoline-2-Il-Methoxy (benzyl-sulfonylureas, their preparation and pharmaceutical preparations containing them IL95391A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927369A DE3927369A1 (de) 1989-08-19 1989-08-19 Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe

Publications (2)

Publication Number Publication Date
IL95391A0 IL95391A0 (en) 1991-06-30
IL95391A true IL95391A (en) 1994-05-30

Family

ID=6387408

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9539190A IL95391A (en) 1989-08-19 1990-08-16 N-) Quinoline-2-Il-Methoxy (benzyl-sulfonylureas, their preparation and pharmaceutical preparations containing them

Country Status (18)

Country Link
US (1) US5179106A (da)
EP (1) EP0414019B1 (da)
JP (1) JPH0390062A (da)
KR (1) KR910004568A (da)
CN (2) CN1040440C (da)
AT (1) ATE138651T1 (da)
AU (1) AU632846B2 (da)
CA (1) CA2023517A1 (da)
DD (1) DD298089A5 (da)
DE (2) DE3927369A1 (da)
DK (1) DK0414019T3 (da)
FI (1) FI904058A0 (da)
HU (1) HU208813B (da)
IE (1) IE902987A1 (da)
IL (1) IL95391A (da)
NZ (1) NZ234931A (da)
PT (1) PT95024A (da)
ZA (1) ZA906531B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3916663A1 (de) * 1989-05-23 1990-11-29 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate
DE4125270A1 (de) * 1991-07-31 1993-02-04 Bayer Ag Chinolin-2-yl-methoxybenzylhydroxyharnstoffe
DE4139750A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Chinolylmethoxyphenylessigsaeure-acylamide und -harnstoffe
EP0562796A1 (en) * 1992-03-23 1993-09-29 Terumo Kabushiki Kaisha Phenoxyacetic acid compounds and medical preparations containing them
DE4226519A1 (de) * 1992-08-11 1994-02-17 Bayer Ag 3-Substituierte Chinolylmethoxy-phenylessigsäurederivate
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
US5612377A (en) * 1994-08-04 1997-03-18 Minnesota Mining And Manufacturing Company Method of inhibiting leukotriene biosynthesis
EP0753499B1 (de) 1995-07-12 2001-06-13 Bayer Ag Verfahren zur Herstellung von Cyclopentylbromid
TR199901816T2 (xx) * 1997-01-29 1999-11-22 Pfizer Inc S�lfonil �re t�revleri, bunlar�n interl�kin-1 aktivitesinin kontrol�nde kullan�mlar�.
CN1295215C (zh) * 2002-12-31 2007-01-17 中国医学科学院药物研究所 黄皮酰胺的光学活性衍生物、其制法和其药物组合物与用途
BRPI0417543A (pt) 2003-12-12 2007-03-27 Wyeth Corp quinolinas úteis no tratamento de doença cardiovascular
CN102101850B (zh) * 2011-03-10 2013-06-12 广州诺浩医药科技有限公司 Swern氧化法制备黄皮酰胺中间体
CN102249976B (zh) 2011-06-10 2012-11-14 中国科学院化学研究所 一种光学纯的（-）-黄皮酰胺类化合物的制备方法
WO2016015333A1 (en) * 2014-08-01 2016-02-04 F.Hoffmann-La Roche Ag 2-oxa-5-azabicyclo [2.2.1] heptan-3-yl derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2948472A1 (de) * 1979-12-01 1981-06-11 Hoechst Ag, 6000 Frankfurt Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung
IE58870B1 (en) * 1985-03-08 1993-11-17 Leo Pharm Prod Ltd Pyridine derivatives
US4876346A (en) * 1985-05-02 1989-10-24 American Home Products Corporation Quinoline compounds
GB2185741B (en) * 1986-01-27 1989-10-25 American Home Prod Heterocyclic sulphonamides
DE3632329A1 (de) * 1986-09-24 1988-03-31 Bayer Ag Substituierte phenylsulfonamide
JPH01502755A (ja) * 1987-03-18 1989-09-21 アメリカン・ホーム・プロダクツ・コーポレイション スルホニルカルボキシアミド
US4920132A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
AU617386B2 (en) * 1987-12-01 1991-11-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Substituted quinolines

Also Published As

Publication number Publication date
DE3927369A1 (de) 1991-02-21
DE59010347D1 (de) 1996-07-04
DD298089A5 (de) 1992-02-06
CN1040440C (zh) 1998-10-28
CN1049656A (zh) 1991-03-06
NZ234931A (en) 1992-07-28
EP0414019B1 (de) 1996-05-29
ATE138651T1 (de) 1996-06-15
HU905055D0 (en) 1991-01-28
DK0414019T3 (da) 1996-10-07
PT95024A (pt) 1991-05-22
IL95391A0 (en) 1991-06-30
HUT54988A (en) 1991-04-29
FI904058A0 (fi) 1990-08-16
EP0414019A2 (de) 1991-02-27
JPH0390062A (ja) 1991-04-16
HU208813B (en) 1994-01-28
CA2023517A1 (en) 1991-02-20
EP0414019A3 (en) 1992-05-13
KR910004568A (ko) 1991-03-28
IE902987A1 (en) 1991-02-27
AU632846B2 (en) 1993-01-14
US5179106A (en) 1993-01-12
AU6114090A (en) 1991-02-21
CN1050022A (zh) 1991-03-20
ZA906531B (en) 1991-06-26

Similar Documents

Publication Publication Date Title
US5179106A (en) Substituted n-(quinolin-2-yl-methoxy) benzyl-sulphonylurea leukotriene synthesis inhibitors
IE62888B1 (en) alfa-substituted 4-(quinolin-2-yl-methoxy) phenylacetic acids and esters
CA2017135C (en) Substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and -cyanamides, processes for their preparation and their use in medicaments
US5192771A (en) (quinolin-2-yl-methoxy)phenylacetic acid derivatives containing cyclic substituents
US5126354A (en) Leukotriene synthesis-inhibiting disubstituted (quinolin-2-yl-methoxy) phenylacetic acid derivatives
AU641585B2 (en) 2-substituted quinolines, process for their preparation and their use in medicaments
US4315940A (en) Antidiabetic 1-piperidine-sulfonylureas
AU660742B2 (en) Thiazolyl-substituted quinolylmethoxphenylacetic acid derivatives
EP0005156B1 (en) 4,5-diaryl-2-(substituted-thio)-pyrroles and their corresponding sulfoxides and sulfones, process for their preparation and pharmaceutical compositions containing them
US5045547A (en) Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas
CA2077465A1 (en) Heterocyclically substituted quinolylmethoxy-phenylacetamides
IL28873A (en) Benzenesulfonyl ureas and process for their manufacture
US4379153A (en) Benzenesulfonyl ureas, and pharmaceutical preparations
IE57330B1 (en) Pyrimidine-thioalkyl pyridine derivatives,a process for their production and medicaments containing these compounds
US4282239A (en) Sulfonyl ureas and pharmaceutical preparations thereof
JPH03145467A (ja) 置換（キノリン―２―イル―メトキシ）フエニル―カルボニル尿素
US5120744A (en) Substituted (quinolin-2-yl-methoxy)phenylthioureas
WO1992020666A1 (en) Benzothiadiazine derivative
US3790630A (en) Benzenesulfonyl-ureas
NZ245326A (en) Quinolylmethoxyphenylacetic acid acylamides and ureas; preparation and pharmaceutical compositions thereof

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void