ZA906531B - Substituted n-(quinolin-2-yl-methoxy)benzyl-sulphonyl-ureas - Google Patents

Substituted n-(quinolin-2-yl-methoxy)benzyl-sulphonyl-ureas

Info

Publication number
ZA906531B
ZA906531B ZA906531A ZA906531A ZA906531B ZA 906531 B ZA906531 B ZA 906531B ZA 906531 A ZA906531 A ZA 906531A ZA 906531 A ZA906531 A ZA 906531A ZA 906531 B ZA906531 B ZA 906531B
Authority
ZA
South Africa
Prior art keywords
quinolin
substituted
sulphonyl
ureas
methoxy
Prior art date
Application number
ZA906531A
Other languages
English (en)
Inventor
Klaus Mohrs
Mohrs Klaus
Siegfried Raddatz
Raddatz Siegfried
Romanis Fruchtmann
Fruchtmann Romanis
Christian Kohlsdorfer
Kohlsdorfer Christian
Reiner Mueller-Peddinghaus
Mueller-Peddinghaus Reiner
Pia Theisen-Popp
Theisen-Popp Pia
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA906531B publication Critical patent/ZA906531B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Quinoline Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA906531A 1989-08-19 1990-08-17 Substituted n-(quinolin-2-yl-methoxy)benzyl-sulphonyl-ureas ZA906531B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927369A DE3927369A1 (de) 1989-08-19 1989-08-19 Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe

Publications (1)

Publication Number Publication Date
ZA906531B true ZA906531B (en) 1991-06-26

Family

ID=6387408

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA906531A ZA906531B (en) 1989-08-19 1990-08-17 Substituted n-(quinolin-2-yl-methoxy)benzyl-sulphonyl-ureas

Country Status (18)

Country Link
US (1) US5179106A (da)
EP (1) EP0414019B1 (da)
JP (1) JPH0390062A (da)
KR (1) KR910004568A (da)
CN (2) CN1040440C (da)
AT (1) ATE138651T1 (da)
AU (1) AU632846B2 (da)
CA (1) CA2023517A1 (da)
DD (1) DD298089A5 (da)
DE (2) DE3927369A1 (da)
DK (1) DK0414019T3 (da)
FI (1) FI904058A0 (da)
HU (1) HU208813B (da)
IE (1) IE902987A1 (da)
IL (1) IL95391A (da)
NZ (1) NZ234931A (da)
PT (1) PT95024A (da)
ZA (1) ZA906531B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3916663A1 (de) * 1989-05-23 1990-11-29 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate
DE4125270A1 (de) * 1991-07-31 1993-02-04 Bayer Ag Chinolin-2-yl-methoxybenzylhydroxyharnstoffe
DE4139750A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Chinolylmethoxyphenylessigsaeure-acylamide und -harnstoffe
EP0562796A1 (en) * 1992-03-23 1993-09-29 Terumo Kabushiki Kaisha Phenoxyacetic acid compounds and medical preparations containing them
DE4226519A1 (de) * 1992-08-11 1994-02-17 Bayer Ag 3-Substituierte Chinolylmethoxy-phenylessigsäurederivate
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
US5612377A (en) * 1994-08-04 1997-03-18 Minnesota Mining And Manufacturing Company Method of inhibiting leukotriene biosynthesis
EP0753499B1 (de) 1995-07-12 2001-06-13 Bayer Ag Verfahren zur Herstellung von Cyclopentylbromid
ES2198598T3 (es) * 1997-01-29 2004-02-01 Pfizer Inc. Derivados de sulfonilurea y su uso en el control de la actividad de la interleuquina-1.
CN1295215C (zh) * 2002-12-31 2007-01-17 中国医学科学院药物研究所 黄皮酰胺的光学活性衍生物、其制法和其药物组合物与用途
KR20070001922A (ko) 2003-12-12 2007-01-04 와이어쓰 심장혈관질환 치료에 유용한 퀴놀린
CN102101850B (zh) * 2011-03-10 2013-06-12 广州诺浩医药科技有限公司 Swern氧化法制备黄皮酰胺中间体
CN102249976B (zh) 2011-06-10 2012-11-14 中国科学院化学研究所 一种光学纯的（-）-黄皮酰胺类化合物的制备方法
WO2016015333A1 (en) * 2014-08-01 2016-02-04 F.Hoffmann-La Roche Ag 2-oxa-5-azabicyclo [2.2.1] heptan-3-yl derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2948472A1 (de) * 1979-12-01 1981-06-11 Hoechst Ag, 6000 Frankfurt Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung
IE58870B1 (en) * 1985-03-08 1993-11-17 Leo Pharm Prod Ltd Pyridine derivatives
US4876346A (en) * 1985-05-02 1989-10-24 American Home Products Corporation Quinoline compounds
GB2185741B (en) * 1986-01-27 1989-10-25 American Home Prod Heterocyclic sulphonamides
DE3632329A1 (de) * 1986-09-24 1988-03-31 Bayer Ag Substituierte phenylsulfonamide
AU1549788A (en) * 1987-03-18 1988-10-10 American Home Products Corporation Sulfonylcarboxamides
US4920132A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
AU617386B2 (en) * 1987-12-01 1991-11-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Substituted quinolines

Also Published As

Publication number Publication date
DD298089A5 (de) 1992-02-06
AU6114090A (en) 1991-02-21
HU208813B (en) 1994-01-28
US5179106A (en) 1993-01-12
JPH0390062A (ja) 1991-04-16
NZ234931A (en) 1992-07-28
AU632846B2 (en) 1993-01-14
KR910004568A (ko) 1991-03-28
CN1049656A (zh) 1991-03-06
FI904058A0 (fi) 1990-08-16
DE3927369A1 (de) 1991-02-21
EP0414019A3 (en) 1992-05-13
CN1040440C (zh) 1998-10-28
HUT54988A (en) 1991-04-29
IL95391A (en) 1994-05-30
DK0414019T3 (da) 1996-10-07
HU905055D0 (en) 1991-01-28
CA2023517A1 (en) 1991-02-20
CN1050022A (zh) 1991-03-20
DE59010347D1 (de) 1996-07-04
IL95391A0 (en) 1991-06-30
EP0414019B1 (de) 1996-05-29
PT95024A (pt) 1991-05-22
EP0414019A2 (de) 1991-02-27
IE902987A1 (en) 1991-02-27
ATE138651T1 (de) 1996-06-15

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