IL93680A - Intracellular MACI-2) 2 molecule and an antibody capable of binding it - Google Patents

Intracellular MACI-2) 2 molecule and an antibody capable of binding it

Info

Publication number
IL93680A
IL93680A IL9368090A IL9368090A IL93680A IL 93680 A IL93680 A IL 93680A IL 9368090 A IL9368090 A IL 9368090A IL 9368090 A IL9368090 A IL 9368090A IL 93680 A IL93680 A IL 93680A
Authority
IL
Israel
Prior art keywords
icam
cell
molecule
antibody
binding
Prior art date
Application number
IL9368090A
Other languages
English (en)
Hebrew (he)
Other versions
IL93680A0 (en
Inventor
Timothy Alan Springer
Michael Loran Dustin
Donald E Staunton
Original Assignee
Blood Res Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blood Res Center filed Critical Blood Res Center
Publication of IL93680A0 publication Critical patent/IL93680A0/xx
Publication of IL93680A publication Critical patent/IL93680A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL9368090A 1989-03-09 1990-03-08 Intracellular MACI-2) 2 molecule and an antibody capable of binding it IL93680A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32123889A 1989-03-09 1989-03-09
US45429489A 1989-12-22 1989-12-22

Publications (2)

Publication Number Publication Date
IL93680A0 IL93680A0 (en) 1990-12-23
IL93680A true IL93680A (en) 1996-01-31

Family

ID=26982877

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9368090A IL93680A (en) 1989-03-09 1990-03-08 Intracellular MACI-2) 2 molecule and an antibody capable of binding it

Country Status (16)

Country Link
EP (1) EP0387668B1 (fr)
JP (1) JP3369166B2 (fr)
KR (1) KR0169728B1 (fr)
AT (1) ATE146222T1 (fr)
AU (1) AU647017B2 (fr)
CA (1) CA2011633C (fr)
DE (1) DE69029336T2 (fr)
DK (1) DK0387668T3 (fr)
ES (1) ES2097747T3 (fr)
FI (1) FI100994B (fr)
GR (1) GR3022670T3 (fr)
HU (1) HU214247B (fr)
IL (1) IL93680A (fr)
MX (1) MX9203469A (fr)
NO (1) NO178862C (fr)
NZ (2) NZ245651A (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
HU217792B (hu) * 1989-03-16 2000-04-28 Dana Farber Cancer Institute Eljárás intercelluláris adhéziós molekula (ICAM-1) oldható származékai és ezeket tartalmazó gyógyszerkészítmények előállítására
ATE184049T1 (de) * 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
EP0510483A1 (fr) * 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Procédé pour la détection des virus
US5460945A (en) * 1991-05-30 1995-10-24 Center For Blood Research, Inc. Device and method for analysis of blood components and identifying inhibitors and promoters of the inflammatory response
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
EP0590051A4 (fr) * 1991-06-11 1994-10-12 Blood Res Center Molecules d'adhesion intracellulaire icam-3 et leurs ligands de fixation.
US5861151A (en) * 1991-12-20 1999-01-19 Bristol-Myers Squibb Co Soluble fusion molecules with binding specificity for cell adhesion molecules
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
JP3616090B2 (ja) * 1992-01-27 2005-02-02 イコス コーポレイション 細胞間接着分子関連タンパク質
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5773218A (en) * 1992-01-27 1998-06-30 Icos Corporation Method to identify compounds which modulate ICAM-related protein interactions
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
AU3657893A (en) * 1992-02-28 1993-09-13 Board Of Regents, The University Of Texas System Compositions and methods for the treatment of thermal injury
EP0656789B1 (fr) * 1992-08-21 1997-12-17 Genentech, Inc. Procede pour traiter une affection ayant pour origine l'antigene 1 associe a la fonction lymphocytaire
AU5466794A (en) * 1992-11-18 1994-06-08 Helsinki University Licensing Ltd Oy Peptides from human icam-2 and from human icam-1 and their analogs for use in therapy and diagnosis
WO1997011168A1 (fr) * 1995-09-22 1997-03-27 Relag Pty. Limited Promoteur et ses utilisations
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US6582698B1 (en) 1999-03-19 2003-06-24 Genentech, Inc. Treatment method
ATE439145T1 (de) 1999-03-19 2009-08-15 Genentech Inc Behandlung von lfa-1 assozieerten krankheiten durch gesteigerte dosen von lfa-1 antagonist
WO2005123777A2 (fr) 2004-06-09 2005-12-29 Genentech, Inc. Procede de traitement du granulome annulaire ou sarcoide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2080044T3 (es) * 1987-05-04 1996-02-01 Dana Farber Cancer Inst Inc Moleculas de adhesion intercelular y sus ligandos de fijacion.
AU629189B2 (en) * 1987-05-04 1992-10-01 Dana-Farber Cancer Institute Intercellular adhesion molecules and their binding ligands
WO1989008114A1 (fr) * 1988-02-25 1989-09-08 The General Hospital Corporation Procede de clonage par immunoselection rapide
ES2177695T3 (es) * 1989-03-16 2002-12-16 Blood Res Center Uso de derivados funcionales de la molecual de adhesion intercelular icam-1 en terapia antiviral.

Also Published As

Publication number Publication date
HU901367D0 (en) 1990-05-28
NO178862B (no) 1996-03-11
NO178862C (no) 1996-06-19
EP0387668B1 (fr) 1996-12-11
EP0387668A1 (fr) 1990-09-19
FI901170A0 (fi) 1990-03-08
HU214247B (hu) 1998-03-02
JP3369166B2 (ja) 2003-01-20
NO901093L (no) 1990-09-10
KR900013978A (ko) 1990-10-22
KR0169728B1 (ko) 1999-01-15
DE69029336T2 (de) 1997-07-03
ATE146222T1 (de) 1996-12-15
ES2097747T3 (es) 1997-04-16
IL93680A0 (en) 1990-12-23
MX9203469A (es) 1992-07-01
DK0387668T3 (da) 1997-03-03
JPH0361486A (ja) 1991-03-18
CA2011633A1 (fr) 1990-09-09
NZ245651A (en) 1997-06-24
CA2011633C (fr) 2007-05-15
NZ232833A (en) 1993-05-26
FI100994B (fi) 1998-03-31
NO901093D0 (no) 1990-03-08
AU647017B2 (en) 1994-03-17
DE69029336D1 (de) 1997-01-23
GR3022670T3 (en) 1997-05-31
AU5117290A (en) 1990-09-13

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