IL92797A - Substituted benzimidazoles, process for their preparation and pharmaceutical compositions containing such compounds - Google Patents

Substituted benzimidazoles, process for their preparation and pharmaceutical compositions containing such compounds

Info

Publication number
IL92797A
IL92797A IL9279789A IL9279789A IL92797A IL 92797 A IL92797 A IL 92797A IL 9279789 A IL9279789 A IL 9279789A IL 9279789 A IL9279789 A IL 9279789A IL 92797 A IL92797 A IL 92797A
Authority
IL
Israel
Prior art keywords
compound
compounds
preparation
bioavailability
administration
Prior art date
Application number
IL9279789A
Other languages
English (en)
Other versions
IL92797A0 (en
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of IL92797A0 publication Critical patent/IL92797A0/xx
Publication of IL92797A publication Critical patent/IL92797A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9279789A 1988-12-22 1989-12-19 Substituted benzimidazoles, process for their preparation and pharmaceutical compositions containing such compounds IL92797A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19888804628A SE8804628D0 (sv) 1988-12-22 1988-12-22 New compounds

Publications (2)

Publication Number Publication Date
IL92797A0 IL92797A0 (en) 1990-09-17
IL92797A true IL92797A (en) 1994-12-29

Family

ID=20374309

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9279789A IL92797A (en) 1988-12-22 1989-12-19 Substituted benzimidazoles, process for their preparation and pharmaceutical compositions containing such compounds

Country Status (26)

Country Link
US (1) US5019584A (no)
EP (1) EP0451188B1 (no)
JP (1) JP2793907B2 (no)
CN (1) CN1028232C (no)
AT (1) ATE110379T1 (no)
AU (1) AU636866B2 (no)
CA (1) CA2005987C (no)
DD (1) DD296077A5 (no)
DE (1) DE68917738T2 (no)
DK (1) DK170801B1 (no)
FI (1) FI913036A0 (no)
GR (1) GR1000318B (no)
HU (1) HUT57203A (no)
IE (1) IE64850B1 (no)
IL (1) IL92797A (no)
LT (1) LT3981B (no)
LV (1) LV10268B (no)
NO (1) NO178338C (no)
PH (1) PH27257A (no)
PT (1) PT92647B (no)
RO (1) RO110496B1 (no)
RU (1) RU2070199C1 (no)
SE (1) SE8804628D0 (no)
WO (1) WO1990006926A1 (no)
YU (1) YU242589A (no)
ZA (1) ZA899796B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE184602T1 (de) * 1990-06-20 1999-10-15 Astra Ab Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
US6016044A (en) * 1995-09-11 2000-01-18 Alaris Medical Systems, Inc. Open-loop step motor control system
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
JP2005521662A (ja) * 2002-01-25 2005-07-21 サンタラス インコーポレイティッド プロトンポンプ阻害剤の経粘膜送達
WO2003082858A1 (en) * 2002-03-26 2003-10-09 Dr. Reddy's Laboratories Limited Crystalline forms of rabeprazole sodium
WO2004073654A2 (en) * 2003-02-20 2004-09-02 Santarus, Inc. A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
TWI337877B (en) * 2003-07-18 2011-03-01 Santarus Inc Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AR045062A1 (es) * 2003-07-18 2005-10-12 Santarus Inc Formulaciones farmaceuticas para inhibir la secrecion de acido y metodos para preparar y utilizarlas
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (no) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4331671A (en) * 1981-01-09 1982-05-25 Sterling Drug Inc. 5-(Pyridinyl)-1H-benzimidazoles and 1-hydroxy-6-(pyridinyl)-1H-benzimidazoles and their cardiotonic use
HU195220B (en) 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150979A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
GB8610607D0 (en) * 1986-04-30 1986-06-04 Smith Kline French Lab Chemical compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
EP0338066A1 (en) * 1987-10-30 1989-10-25 Aktiebolaget Hässle 2-pyridinylmethyl (sulfinyl or thio)benzimidazoles for treatment of diseases related to bone loss

Also Published As

Publication number Publication date
CN1043714A (zh) 1990-07-11
JP2793907B2 (ja) 1998-09-03
LT3981B (en) 1996-06-25
NO912416D0 (no) 1991-06-20
SE8804628D0 (sv) 1988-12-22
ZA899796B (en) 1990-08-29
DE68917738D1 (de) 1994-09-29
ATE110379T1 (de) 1994-09-15
DD296077A5 (de) 1991-11-21
FI913036A0 (fi) 1991-06-20
GR1000318B (el) 1992-06-25
AU636866B2 (en) 1993-05-13
DK170801B1 (da) 1996-01-22
LV10268B (en) 1995-02-20
US5019584A (en) 1991-05-28
RU2070199C1 (ru) 1996-12-10
JPH04502462A (ja) 1992-05-07
CA2005987C (en) 1999-04-13
EP0451188A1 (en) 1991-10-16
WO1990006926A1 (en) 1990-06-28
HUT57203A (en) 1991-11-28
PT92647A (pt) 1990-06-29
IE64850B1 (en) 1995-09-06
DK122391D0 (da) 1991-06-21
NO178338B (no) 1995-11-27
RO110496B1 (ro) 1996-01-30
CA2005987A1 (en) 1990-06-22
IL92797A0 (en) 1990-09-17
IE894049L (en) 1990-06-22
LTIP1722A (en) 1995-07-25
CN1028232C (zh) 1995-04-19
PT92647B (pt) 1995-09-12
SE8804628A (no) 1988-12-22
HU901085D0 (en) 1991-09-30
NO178338C (no) 1996-03-06
EP0451188B1 (en) 1994-08-24
NO912416L (no) 1991-07-31
DE68917738T2 (de) 1994-12-22
AU4817690A (en) 1990-07-10
GR890100834A (en) 1991-03-15
PH27257A (en) 1993-05-04
DK122391A (da) 1991-06-24
LV10268A (lv) 1994-10-20
YU242589A (en) 1991-04-30

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Legal Events

Date Code Title Description
RH Patent void