IL92735A - Nucleic acid molecules encoding a platelet- derived endothelial cell growth factor, process for the purification thereof and therapeutic compositions containing the same - Google Patents

Nucleic acid molecules encoding a platelet- derived endothelial cell growth factor, process for the purification thereof and therapeutic compositions containing the same

Info

Publication number
IL92735A
IL92735A IL92735A IL9273589A IL92735A IL 92735 A IL92735 A IL 92735A IL 92735 A IL92735 A IL 92735A IL 9273589 A IL9273589 A IL 9273589A IL 92735 A IL92735 A IL 92735A
Authority
IL
Israel
Prior art keywords
subjecting
purification
pooling
growth factor
cell growth
Prior art date
Application number
IL92735A
Other languages
English (en)
Other versions
IL92735A0 (en
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Publication of IL92735A0 publication Critical patent/IL92735A0/xx
Publication of IL92735A publication Critical patent/IL92735A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL92735A 1988-12-20 1989-12-15 Nucleic acid molecules encoding a platelet- derived endothelial cell growth factor, process for the purification thereof and therapeutic compositions containing the same IL92735A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28805688A 1988-12-20 1988-12-20

Publications (2)

Publication Number Publication Date
IL92735A0 IL92735A0 (en) 1990-09-17
IL92735A true IL92735A (en) 1998-06-15

Family

ID=23105561

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92735A IL92735A (en) 1988-12-20 1989-12-15 Nucleic acid molecules encoding a platelet- derived endothelial cell growth factor, process for the purification thereof and therapeutic compositions containing the same

Country Status (13)

Country Link
EP (2) EP0685490A1 (da)
JP (1) JPH02288897A (da)
KR (1) KR900009989A (da)
AT (1) ATE145242T1 (da)
AU (1) AU4687989A (da)
CA (1) CA2005600A1 (da)
DE (1) DE68927458T2 (da)
DK (1) DK643389A (da)
FI (1) FI896137A7 (da)
IL (1) IL92735A (da)
NO (1) NO895055L (da)
NZ (1) NZ231837A (da)
PT (1) PT92613B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI890342L (fi) * 1988-01-25 1989-07-26 American Cyanamid Co Hjaernmitogener, som binds till heparin.
CA2005600A1 (en) 1988-12-20 1990-06-20 Cal-Henrik Heldin Endothelial cell growth factor
ES2123004T3 (es) * 1991-04-12 1999-01-01 Creative Biomolecules Inc Uso de factor de crecimiento derivado de plaquetas en la preparacion de un medicamento para el tratamiento de ulceras gastrointestinales.
DE4118912C1 (da) * 1991-06-08 1992-07-02 Biotest Pharma Gmbh, 6072 Dreieich, De
GB9121815D0 (en) * 1991-10-15 1991-11-27 Delta Biotechnology Ltd Medicine
EP0697883A1 (en) * 1993-04-29 1996-02-28 Washington University Use of platelet-derived growth factor to improve collateral circulation
JP3268147B2 (ja) * 1994-12-28 2002-03-25 大鵬薬品工業株式会社 モノクローナル抗体
AU729459B2 (en) * 1996-11-15 2001-02-01 Genentech Inc. Purification of neurotrophins
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
AUPP263498A0 (en) * 1998-03-27 1998-04-23 Walter And Eliza Hall Institute Of Medical Research, The Novel therapeutic molecules and uses therefor
ES2402144T3 (es) * 2010-05-25 2013-04-29 Gwowei Technology Co., Ltd. Lisado plaquetario inactivado que contiene factores de crecimiento empobrecido en PDGF y VEGF y su procedimiento de preparación
WO2012102100A1 (ja) 2011-01-26 2012-08-02 雪印メグミルク株式会社 感覚改善剤
HK1221402A1 (zh) 2013-04-02 2017-06-02 University Of Florida Research Foundation, Inc. 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2005600A1 (en) 1988-12-20 1990-06-20 Cal-Henrik Heldin Endothelial cell growth factor

Also Published As

Publication number Publication date
DK643389A (da) 1990-06-21
DE68927458D1 (de) 1996-12-19
JPH02288897A (ja) 1990-11-28
PT92613B (pt) 1996-09-30
DK643389D0 (da) 1989-12-18
FI896137A7 (fi) 1990-06-21
EP0377855A2 (en) 1990-07-18
EP0685490A1 (en) 1995-12-06
EP0377855A3 (en) 1990-12-19
DE68927458T2 (de) 1997-04-03
CA2005600A1 (en) 1990-06-20
PT92613A (pt) 1990-06-29
KR900009989A (ko) 1990-07-06
NO895055D0 (no) 1989-12-15
IL92735A0 (en) 1990-09-17
EP0377855B1 (en) 1996-11-13
FI896137A0 (fi) 1989-12-20
AU4687989A (en) 1990-06-28
ATE145242T1 (de) 1996-11-15
NZ231837A (en) 1992-03-26
NO895055L (no) 1990-06-21

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees