IL92729A0 - 2-aminopyrimidinone derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
2-aminopyrimidinone derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL92729A0 IL92729A0 IL92729A IL9272989A IL92729A0 IL 92729 A0 IL92729 A0 IL 92729A0 IL 92729 A IL92729 A IL 92729A IL 9272989 A IL9272989 A IL 9272989A IL 92729 A0 IL92729 A0 IL 92729A0
- Authority
- IL
- Israel
- Prior art keywords
- 6alkyl
- hydrogen
- pharmaceutical compositions
- compositions containing
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898900380A GB8900380D0 (en) | 1989-01-09 | 1989-01-09 | 2-aminopyrimidinone derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IL92729A0 true IL92729A0 (en) | 1990-09-17 |
Family
ID=10649777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL92729A IL92729A0 (en) | 1989-01-09 | 1989-12-15 | 2-aminopyrimidinone derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (20)
Country | Link |
---|---|
US (1) | US5008268A (xx) |
EP (1) | EP0378254B1 (xx) |
JP (1) | JPH02233678A (xx) |
CN (1) | CN1030452C (xx) |
AT (1) | ATE107642T1 (xx) |
AU (1) | AU622509B2 (xx) |
CA (1) | CA2007198A1 (xx) |
DE (1) | DE69010015T2 (xx) |
DK (1) | DK0378254T3 (xx) |
ES (1) | ES2058749T3 (xx) |
FI (1) | FI94526C (xx) |
GB (1) | GB8900380D0 (xx) |
HU (1) | HU206350B (xx) |
IE (1) | IE63153B1 (xx) |
IL (1) | IL92729A0 (xx) |
NO (1) | NO172645C (xx) |
NZ (1) | NZ231787A (xx) |
PH (1) | PH26908A (xx) |
RU (1) | RU1825364C (xx) |
ZA (1) | ZA90120B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0347146B1 (en) * | 1988-06-16 | 1993-09-01 | Smith Kline & French Laboratories Limited | Fused pyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them |
GB8900382D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
CA2043564A1 (en) * | 1990-07-06 | 1992-01-07 | Alfons G. M. De Knaep | 3-[(5-methyl-2-furanyl)methyl]-n-(4-piperidinyl)-3h-imidazo [4,5-b]-pyridin-2-amine 2-hydroxy-1,2,3-propanetricarboxylate |
NZ238863A (en) * | 1990-07-19 | 1993-03-26 | Janssen Pharmaceutica Nv | Substituted thiazolyl and pyridinyl derivatives |
IL101851A (en) * | 1991-06-13 | 1996-05-14 | Janssen Pharmaceutica Nv | History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition |
IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
AU3347493A (en) * | 1992-01-09 | 1993-08-03 | Janssen Pharmaceutica N.V. | Pharmaceutically active substituted benzimidazole derivatives |
GR1001393B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο[2,1-Β] 3] βενζαζεπίνης, συν?έσεις και μέ?οδος χρήσεως. |
GR1001385B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως. |
US5521183A (en) * | 1994-08-30 | 1996-05-28 | Allergan | Use of 5-HT ligands as anti-pruritic agents |
US6211199B1 (en) | 1995-11-17 | 2001-04-03 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
US5922737A (en) * | 1996-02-21 | 1999-07-13 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases |
US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
US5998439A (en) * | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
EP3150209B1 (en) | 2006-03-31 | 2019-07-24 | Vistakon Pharmaceuticals, LLC | Ocular allergy treatments |
CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
CN112574219A (zh) * | 2021-01-31 | 2021-03-30 | 湖北大学 | 一种苯并咪唑并嘧啶酮衍生物的合成方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
US4695569A (en) * | 1983-11-30 | 1987-09-22 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines |
EP0144101B1 (en) * | 1983-11-30 | 1991-02-06 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines |
US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
US4835161A (en) * | 1986-02-03 | 1989-05-30 | Janssen Pharmaceutica N.V. | Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines |
NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
US4897401A (en) * | 1987-06-19 | 1990-01-30 | Janssen Pharmaceutical N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases |
EP0297742A3 (en) * | 1987-06-22 | 1990-05-16 | Elopak Systems Ag | Flat top end closure for liquid containers |
CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
GB8716313D0 (en) * | 1987-07-10 | 1987-08-19 | Janssen Pharmaceutica Nv | 2-(heterocyclylalkyl)imidazopyridines |
-
1989
- 1989-01-09 GB GB898900380A patent/GB8900380D0/en active Pending
- 1989-12-14 NZ NZ231787A patent/NZ231787A/en unknown
- 1989-12-15 IL IL92729A patent/IL92729A0/xx not_active IP Right Cessation
- 1989-12-26 US US07/456,391 patent/US5008268A/en not_active Expired - Fee Related
-
1990
- 1990-01-03 DE DE69010015T patent/DE69010015T2/de not_active Expired - Fee Related
- 1990-01-03 EP EP90200004A patent/EP0378254B1/en not_active Expired - Lifetime
- 1990-01-03 AT AT90200004T patent/ATE107642T1/de not_active IP Right Cessation
- 1990-01-03 DK DK90200004.1T patent/DK0378254T3/da active
- 1990-01-03 ES ES90200004T patent/ES2058749T3/es not_active Expired - Lifetime
- 1990-01-05 CA CA002007198A patent/CA2007198A1/en not_active Abandoned
- 1990-01-08 AU AU47780/90A patent/AU622509B2/en not_active Ceased
- 1990-01-08 FI FI900084A patent/FI94526C/fi not_active IP Right Cessation
- 1990-01-08 IE IE6890A patent/IE63153B1/en not_active IP Right Cessation
- 1990-01-08 NO NO900070A patent/NO172645C/no unknown
- 1990-01-08 HU HU9063A patent/HU206350B/hu not_active IP Right Cessation
- 1990-01-08 ZA ZA90120A patent/ZA90120B/xx unknown
- 1990-01-08 RU SU904742861A patent/RU1825364C/ru active
- 1990-01-08 PH PH39860A patent/PH26908A/en unknown
- 1990-01-09 CN CN90100077A patent/CN1030452C/zh not_active Expired - Fee Related
- 1990-01-09 JP JP2002414A patent/JPH02233678A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2007198A1 (en) | 1990-07-09 |
CN1030452C (zh) | 1995-12-06 |
HU900063D0 (en) | 1990-03-28 |
PH26908A (en) | 1992-12-03 |
FI900084A (fi) | 1990-07-10 |
IE63153B1 (en) | 1995-03-22 |
CN1044099A (zh) | 1990-07-25 |
AU622509B2 (en) | 1992-04-09 |
HU206350B (en) | 1992-10-28 |
DE69010015T2 (de) | 1994-11-24 |
ES2058749T3 (es) | 1994-11-01 |
FI900084A0 (fi) | 1990-01-08 |
AU4778090A (en) | 1990-07-12 |
FI94526B (fi) | 1995-06-15 |
NO900070D0 (no) | 1990-01-08 |
NZ231787A (en) | 1991-07-26 |
NO900070L (no) | 1990-07-10 |
FI94526C (fi) | 1995-09-25 |
RU1825364C (ru) | 1993-06-30 |
GB8900380D0 (en) | 1989-03-08 |
DK0378254T3 (da) | 1994-07-25 |
ATE107642T1 (de) | 1994-07-15 |
HUT53364A (en) | 1990-10-28 |
EP0378254A2 (en) | 1990-07-18 |
JPH02233678A (ja) | 1990-09-17 |
EP0378254A3 (en) | 1991-01-09 |
EP0378254B1 (en) | 1994-06-22 |
US5008268A (en) | 1991-04-16 |
DE69010015D1 (de) | 1994-07-28 |
NO172645C (no) | 1993-08-18 |
ZA90120B (en) | 1991-09-25 |
NO172645B (no) | 1993-05-10 |
IE900068L (en) | 1990-07-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL92729A0 (en) | 2-aminopyrimidinone derivatives,their preparation and pharmaceutical compositions containing them | |
IL92730A0 (en) | 2-aminopyrimidinone derivatives,their preparation and pharmaceutical compositions containing them | |
ZA884696B (en) | ((bicyclic heterocyclyl)methyl and-hetero)substituted hexahydro-1h-azepines and pyrrolidines | |
IL86788A (en) | N-(4-piperidinyl)bicyclic condensed 2-imidazolamine derivatives,their preparation and pharmaceutical compositions containing them | |
IL94008A (en) | Hydroxyalkylfuranyl derivatives their preparation and pharmaceutical compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |