FI900084A0 - Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsol-2-yyli- ja imidatso/4,5-b/pyridin-2-yyli-amino- ja -metyyli-1-piperidinyylietyylijohdannaisten valmistamiseksi - Google Patents
Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsol-2-yyli- ja imidatso/4,5-b/pyridin-2-yyli-amino- ja -metyyli-1-piperidinyylietyylijohdannaisten valmistamiseksiInfo
- Publication number
- FI900084A0 FI900084A0 FI900084A FI900084A FI900084A0 FI 900084 A0 FI900084 A0 FI 900084A0 FI 900084 A FI900084 A FI 900084A FI 900084 A FI900084 A FI 900084A FI 900084 A0 FI900084 A0 FI 900084A0
- Authority
- FI
- Finland
- Prior art keywords
- 6alkyl
- hydrogen
- methyl
- derivatives
- piperidinylethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898900380A GB8900380D0 (en) | 1989-01-09 | 1989-01-09 | 2-aminopyrimidinone derivatives |
| GB8900380 | 1989-01-09 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI900084A0 true FI900084A0 (fi) | 1990-01-08 |
| FI900084A FI900084A (fi) | 1990-07-10 |
| FI94526B FI94526B (fi) | 1995-06-15 |
| FI94526C FI94526C (fi) | 1995-09-25 |
Family
ID=10649777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI900084A FI94526C (fi) | 1989-01-09 | 1990-01-08 | Menetelmä terapeuttisesti käyttökelpoisten bentsimidatsol-2-yyli- ja imidatso/4,5-b/pyridin-2-yyli-amino- ja -metyyli-1-piperidinyylietyylijohdannaisten valmistamiseksi |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5008268A (fi) |
| EP (1) | EP0378254B1 (fi) |
| JP (1) | JPH02233678A (fi) |
| CN (1) | CN1030452C (fi) |
| AT (1) | ATE107642T1 (fi) |
| AU (1) | AU622509B2 (fi) |
| CA (1) | CA2007198A1 (fi) |
| DE (1) | DE69010015T2 (fi) |
| DK (1) | DK0378254T3 (fi) |
| ES (1) | ES2058749T3 (fi) |
| FI (1) | FI94526C (fi) |
| GB (1) | GB8900380D0 (fi) |
| HU (1) | HU206350B (fi) |
| IE (1) | IE63153B1 (fi) |
| IL (1) | IL92729A0 (fi) |
| NO (1) | NO172645C (fi) |
| NZ (1) | NZ231787A (fi) |
| PH (1) | PH26908A (fi) |
| RU (1) | RU1825364C (fi) |
| ZA (1) | ZA90120B (fi) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2058527T3 (es) * | 1988-06-16 | 1994-11-01 | Smith Kline French Lab | Derivados de pirimidina condensados procedimiento y compuestos intermedios para su preparacion y composiciones farmaceuticas que los contienen. |
| GB8900382D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
| CA2043564A1 (en) * | 1990-07-06 | 1992-01-07 | Alfons G. M. De Knaep | 3-[(5-methyl-2-furanyl)methyl]-n-(4-piperidinyl)-3h-imidazo [4,5-b]-pyridin-2-amine 2-hydroxy-1,2,3-propanetricarboxylate |
| NZ238863A (en) * | 1990-07-19 | 1993-03-26 | Janssen Pharmaceutica Nv | Substituted thiazolyl and pyridinyl derivatives |
| IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
| IL101851A (en) * | 1991-06-13 | 1996-05-14 | Janssen Pharmaceutica Nv | History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition |
| TW231291B (fi) * | 1992-01-09 | 1994-10-01 | Janssen Pharmaceutica Nv | |
| GR1001393B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο[2,1-Β] 3] βενζαζεπίνης, συν?έσεις και μέ?οδος χρήσεως. |
| GR1001385B (el) * | 1992-10-12 | 1993-10-29 | Janssen Pharmaceutica Nv | Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως. |
| US5521183A (en) * | 1994-08-30 | 1996-05-28 | Allergan | Use of 5-HT ligands as anti-pruritic agents |
| US6211199B1 (en) | 1995-11-17 | 2001-04-03 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US5922737A (en) * | 1996-02-21 | 1999-07-13 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| US5998439A (en) | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
| EP2004196B1 (en) | 2006-03-31 | 2016-06-29 | Vistakon Pharmaceuticals, LLC | Ocular allergy treatments |
| CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
| CN112574219A (zh) * | 2021-01-31 | 2021-03-30 | 湖北大学 | 一种苯并咪唑并嘧啶酮衍生物的合成方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
| US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
| US4695569A (en) * | 1983-11-30 | 1987-09-22 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines |
| EP0144101B1 (en) * | 1983-11-30 | 1991-02-06 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines |
| PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
| US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
| US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
| US4835161A (en) * | 1986-02-03 | 1989-05-30 | Janssen Pharmaceutica N.V. | Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines |
| NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
| US4897401A (en) * | 1987-06-19 | 1990-01-30 | Janssen Pharmaceutical N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases |
| EP0297742A3 (en) * | 1987-06-22 | 1990-05-16 | Elopak Systems Ag | Flat top end closure for liquid containers |
| CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
| GB8716313D0 (en) * | 1987-07-10 | 1987-08-19 | Janssen Pharmaceutica Nv | 2-(heterocyclylalkyl)imidazopyridines |
-
1989
- 1989-01-09 GB GB898900380A patent/GB8900380D0/en active Pending
- 1989-12-14 NZ NZ231787A patent/NZ231787A/en unknown
- 1989-12-15 IL IL92729A patent/IL92729A0/xx not_active IP Right Cessation
- 1989-12-26 US US07/456,391 patent/US5008268A/en not_active Expired - Fee Related
-
1990
- 1990-01-03 DE DE69010015T patent/DE69010015T2/de not_active Expired - Fee Related
- 1990-01-03 ES ES90200004T patent/ES2058749T3/es not_active Expired - Lifetime
- 1990-01-03 DK DK90200004.1T patent/DK0378254T3/da active
- 1990-01-03 EP EP90200004A patent/EP0378254B1/en not_active Expired - Lifetime
- 1990-01-03 AT AT90200004T patent/ATE107642T1/de not_active IP Right Cessation
- 1990-01-05 CA CA002007198A patent/CA2007198A1/en not_active Abandoned
- 1990-01-08 AU AU47780/90A patent/AU622509B2/en not_active Ceased
- 1990-01-08 ZA ZA90120A patent/ZA90120B/xx unknown
- 1990-01-08 IE IE6890A patent/IE63153B1/en not_active IP Right Cessation
- 1990-01-08 NO NO900070A patent/NO172645C/no unknown
- 1990-01-08 FI FI900084A patent/FI94526C/fi not_active IP Right Cessation
- 1990-01-08 PH PH39860A patent/PH26908A/en unknown
- 1990-01-08 RU SU904742861A patent/RU1825364C/ru active
- 1990-01-08 HU HU9063A patent/HU206350B/hu not_active IP Right Cessation
- 1990-01-09 JP JP2002414A patent/JPH02233678A/ja active Pending
- 1990-01-09 CN CN90100077A patent/CN1030452C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU206350B (en) | 1992-10-28 |
| EP0378254A3 (en) | 1991-01-09 |
| DE69010015D1 (de) | 1994-07-28 |
| DK0378254T3 (da) | 1994-07-25 |
| NO900070D0 (no) | 1990-01-08 |
| HU900063D0 (en) | 1990-03-28 |
| FI94526C (fi) | 1995-09-25 |
| NO172645C (no) | 1993-08-18 |
| CN1044099A (zh) | 1990-07-25 |
| IL92729A0 (en) | 1990-09-17 |
| NZ231787A (en) | 1991-07-26 |
| NO172645B (no) | 1993-05-10 |
| ZA90120B (en) | 1991-09-25 |
| ATE107642T1 (de) | 1994-07-15 |
| NO900070L (no) | 1990-07-10 |
| AU622509B2 (en) | 1992-04-09 |
| ES2058749T3 (es) | 1994-11-01 |
| IE900068L (en) | 1990-07-09 |
| EP0378254B1 (en) | 1994-06-22 |
| DE69010015T2 (de) | 1994-11-24 |
| AU4778090A (en) | 1990-07-12 |
| HUT53364A (en) | 1990-10-28 |
| PH26908A (en) | 1992-12-03 |
| EP0378254A2 (en) | 1990-07-18 |
| JPH02233678A (ja) | 1990-09-17 |
| RU1825364C (ru) | 1993-06-30 |
| GB8900380D0 (en) | 1989-03-08 |
| CA2007198A1 (en) | 1990-07-09 |
| US5008268A (en) | 1991-04-16 |
| IE63153B1 (en) | 1995-03-22 |
| FI900084A (fi) | 1990-07-10 |
| FI94526B (fi) | 1995-06-15 |
| CN1030452C (zh) | 1995-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed |
Owner name: JANSSEN PHARMACEUTICA N.V. |