IL92671A0 - Pharmaceutical compositions containing peptide isosteres as retroviral protease inhibitors - Google Patents
Pharmaceutical compositions containing peptide isosteres as retroviral protease inhibitorsInfo
- Publication number
- IL92671A0 IL92671A0 IL92671A IL9267189A IL92671A0 IL 92671 A0 IL92671 A0 IL 92671A0 IL 92671 A IL92671 A IL 92671A IL 9267189 A IL9267189 A IL 9267189A IL 92671 A0 IL92671 A0 IL 92671A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- protease inhibitors
- containing peptide
- retroviral protease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/553—Renin inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH464188 | 1988-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL92671A0 true IL92671A0 (en) | 1990-09-17 |
Family
ID=4279922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL92671A IL92671A0 (en) | 1988-12-15 | 1989-12-13 | Pharmaceutical compositions containing peptide isosteres as retroviral protease inhibitors |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0374097A3 (en) |
JP (1) | JPH02212434A (en) |
AU (1) | AU4678589A (en) |
CA (1) | CA2005337A1 (en) |
DK (1) | DK633189A (en) |
IL (1) | IL92671A0 (en) |
ZA (1) | ZA899559B (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1340682C (en) * | 1989-07-07 | 1999-07-27 | Pierre Lavallee | Antiviral peptides having a 2-oxoalkyl amino acid side chain |
DE4001236A1 (en) * | 1990-01-18 | 1991-07-25 | Bayer Ag | New oligopeptide(s) contg. 2-amino-2-methyl propionic acid residue - are antiviral agents for human or veterinary therapy including treatment of AIDS and ARC |
CA2036413C (en) * | 1990-02-23 | 2000-12-12 | Paul Cates Anderson | Hiv protease inhibitors |
CA2036398C (en) * | 1990-02-23 | 2000-06-13 | Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee | Hiv protease inhibiting agents |
CA2036397C (en) * | 1990-02-23 | 2000-12-12 | Paul Cates Anderson | Hiv protease inhibitors containing derived amino acid units |
IL98260A0 (en) * | 1990-06-01 | 1992-06-21 | Ciba Geigy Ag | Hiv protease inhibiting oligopeptides,process for their preparation and pharmaceutical compositions containing them |
ATE216371T1 (en) | 1991-10-11 | 2002-05-15 | Du Pont Pharm Co | CYCLIC UREAS AND ANALOGUES USABLE AS RETROVIRAL PROTEASE INHIBITORS |
AU3240493A (en) * | 1991-12-12 | 1993-07-19 | Schering Corporation | Compounds and compositions for treating HIV infections |
CA2091151A1 (en) * | 1992-03-13 | 1993-09-14 | Kwan Y. Hui | Retroviral protease inhibitors |
TW217410B (en) * | 1992-04-01 | 1993-12-11 | Ciba Geigy | |
CA2131182C (en) * | 1992-05-20 | 2005-04-26 | John S. Ng | Method for making intermediates useful in synthesis of retroviral protease inhibitors |
US5559256A (en) * | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
US5385918A (en) * | 1993-02-09 | 1995-01-31 | Miles Inc. | Aminomethylene-peptides as immunosuppressants |
EP0610744B1 (en) * | 1993-02-09 | 1998-11-04 | Bayer Corporation | Sulfonamide aminomethylene derivatives as immunosuppressants |
EP0610745A3 (en) * | 1993-02-09 | 1994-09-28 | Miles Inc | Novel aminomethylene derivatives as immunosuppressants. |
US5686469A (en) * | 1993-02-09 | 1997-11-11 | Miles Inc. | Aminomethylene derivaties as immunosuppressants |
WO1994022906A1 (en) * | 1993-03-26 | 1994-10-13 | Warner-Lambert Company | Inhibitors of endothelin converting enzyme |
DE4332395A1 (en) * | 1993-09-23 | 1995-04-13 | Horst Dr Lindhofer | Inhibitors for the zymogen-like liberation cleavage of HIV-1 protease |
PT708085E (en) * | 1994-10-19 | 2002-11-29 | Novartis Ag | PROTEASE ASPARTATE SUBSTRATE ISOSTERATE ETERIS ANTERIORS |
CA2191924A1 (en) * | 1995-12-05 | 1997-06-06 | Kevin Felsenstein | 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of .beta.-amyloid protein production |
US5703129A (en) * | 1996-09-30 | 1997-12-30 | Bristol-Myers Squibb Company | 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU573735B2 (en) * | 1983-02-07 | 1988-06-23 | Aktiebolaget Hassle | Peptide analogue enzyme inhibitors |
US4727060A (en) * | 1984-11-13 | 1988-02-23 | Ciba-Geigy Corporation | Novel 5-amino-4-hydroxyvaleryl derivatives |
FR2614533A1 (en) * | 1987-04-23 | 1988-11-04 | Sandoz Sa | NOVEL PEPTIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
-
1989
- 1989-12-06 EP EP19890810922 patent/EP0374097A3/en not_active Withdrawn
- 1989-12-13 IL IL92671A patent/IL92671A0/en unknown
- 1989-12-13 CA CA002005337A patent/CA2005337A1/en not_active Abandoned
- 1989-12-14 ZA ZA899559A patent/ZA899559B/en unknown
- 1989-12-14 AU AU46785/89A patent/AU4678589A/en not_active Abandoned
- 1989-12-14 DK DK633189A patent/DK633189A/en not_active Application Discontinuation
- 1989-12-15 JP JP1324110A patent/JPH02212434A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2005337A1 (en) | 1990-06-15 |
EP0374097A2 (en) | 1990-06-20 |
ZA899559B (en) | 1990-08-29 |
DK633189D0 (en) | 1989-12-14 |
AU4678589A (en) | 1990-06-21 |
EP0374097A3 (en) | 1991-06-12 |
JPH02212434A (en) | 1990-08-23 |
DK633189A (en) | 1990-06-16 |
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