IL98260A0 - Hiv protease inhibiting oligopeptides,process for their preparation and pharmaceutical compositions containing them - Google Patents

Hiv protease inhibiting oligopeptides,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL98260A0
IL98260A0 IL98260A IL9826091A IL98260A0 IL 98260 A0 IL98260 A0 IL 98260A0 IL 98260 A IL98260 A IL 98260A IL 9826091 A IL9826091 A IL 9826091A IL 98260 A0 IL98260 A0 IL 98260A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
hiv protease
protease inhibiting
Prior art date
Application number
IL98260A
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL98260A0 publication Critical patent/IL98260A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02Peptides being immobilised on, or in, an organic carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL98260A 1990-06-01 1991-05-24 Hiv protease inhibiting oligopeptides,process for their preparation and pharmaceutical compositions containing them IL98260A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH186090 1990-06-01

Publications (1)

Publication Number Publication Date
IL98260A0 true IL98260A0 (en) 1992-06-21

Family

ID=4220305

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98260A IL98260A0 (en) 1990-06-01 1991-05-24 Hiv protease inhibiting oligopeptides,process for their preparation and pharmaceutical compositions containing them

Country Status (9)

Country Link
EP (1) EP0459465A3 (en)
JP (1) JPH04235999A (en)
KR (1) KR920000790A (en)
AU (1) AU7732691A (en)
CA (1) CA2043603A1 (en)
IE (1) IE911873A1 (en)
IL (1) IL98260A0 (en)
PT (1) PT97782A (en)
ZA (1) ZA914136B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643878A (en) * 1991-09-12 1997-07-01 Ciba-Geigy Corporation 5-amino-4-hydroxyhexanoic acid derivatives
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
MXPA93002392A (en) 1992-03-11 2005-02-04 Narhex Ltd Amine derivatives of oxo- and hydroxy-substitued hydrocarbons.
EP0633881B1 (en) * 1992-03-11 2003-10-29 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
TW217410B (en) * 1992-04-01 1993-12-11 Ciba Geigy
DE4215874A1 (en) * 1992-05-14 1993-11-18 Bayer Ag Dithiolanylglycine-containing HIV protease inhibitors of the hydroxyethylene isostear type
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
EP0626178A1 (en) * 1993-05-17 1994-11-30 Ciba-Geigy Ag Use of inhibitors of HIV-protease for the treatment of tumorous diseases
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
EP0374098A3 (en) * 1988-12-15 1991-05-02 Ciba-Geigy Ag Inhibitors of retroviral proteases
EP0374097A3 (en) * 1988-12-15 1991-06-12 Ciba-Geigy Ag Use of peptide isosteres as retroviral protease inhibitors

Also Published As

Publication number Publication date
PT97782A (en) 1992-02-28
ZA914136B (en) 1992-02-26
KR920000790A (en) 1992-01-29
IE911873A1 (en) 1991-12-04
AU7732691A (en) 1991-12-05
EP0459465A2 (en) 1991-12-04
JPH04235999A (en) 1992-08-25
CA2043603A1 (en) 1991-12-02
EP0459465A3 (en) 1992-12-23

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