IL92315A - הכנת היפריצין מאמודין אנתרון - Google Patents

הכנת היפריצין מאמודין אנתרון

Info

Publication number
IL92315A
IL92315A IL9231589A IL9231589A IL92315A IL 92315 A IL92315 A IL 92315A IL 9231589 A IL9231589 A IL 9231589A IL 9231589 A IL9231589 A IL 9231589A IL 92315 A IL92315 A IL 92315A
Authority
IL
Israel
Prior art keywords
oxide
process according
hypericin
pyridine
protohypericin
Prior art date
Application number
IL9231589A
Other languages
English (en)
Other versions
IL92315A0 (en
Inventor
Yehuda Mazur
Harald Bock
David Lavie
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL9231589A priority Critical patent/IL92315A/he
Publication of IL92315A0 publication Critical patent/IL92315A0/xx
Priority to US07/613,604 priority patent/US5120412A/en
Priority to AT90121796T priority patent/ATE117978T1/de
Priority to CA002029993A priority patent/CA2029993C/en
Priority to AU66652/90A priority patent/AU629066B2/en
Priority to DK90121796.8T priority patent/DK0432496T3/da
Priority to EP90121796A priority patent/EP0432496B1/en
Priority to ES90121796T priority patent/ES2070244T3/es
Priority to DE69016620T priority patent/DE69016620T2/de
Priority to JP2310109A priority patent/JP2896224B2/ja
Priority to GR950401040T priority patent/GR3015919T3/el
Publication of IL92315A publication Critical patent/IL92315A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
IL9231589A 1989-11-15 1989-11-15 הכנת היפריצין מאמודין אנתרון IL92315A (he)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IL9231589A IL92315A (he) 1989-11-15 1989-11-15 הכנת היפריצין מאמודין אנתרון
US07/613,604 US5120412A (en) 1989-11-15 1990-11-09 Preparation of hypericin
DE69016620T DE69016620T2 (de) 1989-11-15 1990-11-14 Herstellung von Hyperizin.
AU66652/90A AU629066B2 (en) 1989-11-15 1990-11-14 Preparation of hypericin
CA002029993A CA2029993C (en) 1989-11-15 1990-11-14 Preparation of hypericin
AT90121796T ATE117978T1 (de) 1989-11-15 1990-11-14 Herstellung von hyperizin.
DK90121796.8T DK0432496T3 (da) 1989-11-15 1990-11-14 Fremstilling af hypericin
EP90121796A EP0432496B1 (en) 1989-11-15 1990-11-14 Preparation of hypericin
ES90121796T ES2070244T3 (es) 1989-11-15 1990-11-14 Preparado de hypericina.
JP2310109A JP2896224B2 (ja) 1989-11-15 1990-11-15 ヒペリシンの製造法
GR950401040T GR3015919T3 (en) 1989-11-15 1995-04-25 Preparation of hypericin.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL9231589A IL92315A (he) 1989-11-15 1989-11-15 הכנת היפריצין מאמודין אנתרון

Publications (2)

Publication Number Publication Date
IL92315A0 IL92315A0 (en) 1990-07-26
IL92315A true IL92315A (he) 1996-12-05

Family

ID=11060574

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9231589A IL92315A (he) 1989-11-15 1989-11-15 הכנת היפריצין מאמודין אנתרון

Country Status (11)

Country Link
US (1) US5120412A (he)
EP (1) EP0432496B1 (he)
JP (1) JP2896224B2 (he)
AT (1) ATE117978T1 (he)
AU (1) AU629066B2 (he)
CA (1) CA2029993C (he)
DE (1) DE69016620T2 (he)
DK (1) DK0432496T3 (he)
ES (1) ES2070244T3 (he)
GR (1) GR3015919T3 (he)
IL (1) IL92315A (he)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92315A (he) * 1989-11-15 1996-12-05 Yeda Res & Dev הכנת היפריצין מאמודין אנתרון
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
WO1994014427A2 (en) * 1992-12-23 1994-07-07 Zymogenetics, Inc. Use of skyrin and analogues for the treatment of diabetes mellitus and process for their preparation
DE19547317A1 (de) * 1995-12-18 1998-12-24 Dreluso Pharm Dr Elten & Sohn Antivirales Medikament
US6001882A (en) * 1997-07-03 1999-12-14 The Trustees Of The University Of Pennsylvania Photoactivated hypericin and the use thereof
IL121440A0 (en) 1997-07-31 1998-01-04 Yeda Res & Dev The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives
US6238671B1 (en) * 1998-04-22 2001-05-29 Bionorica Arzneimittel Gmbh Process for the gentle recovery of extract fractions from hypericum, pharmaceutical preparations containing the same and their use
EP1094712A4 (en) * 1998-07-09 2004-09-08 Cv Technologies Inc HYPERICIN AND HYPERICUM EXTRACT: AGENTS THAT BLOCK TYPE C CALCIUM CHANNELS AND THEIR USE AS THERAPEUTIC AGENTS DIRECTED AGAINST TYPE T CALCIUM CHANNEL
DE19838377C2 (de) * 1998-08-24 2000-10-26 Fiegert Seibt Edda Verfahren und Vorrichtung zur Extraktherstellung aus pflanzlichem Material
US7195783B2 (en) * 1999-07-09 2007-03-27 Fx Life Sciences International Gmbh Hypericin and hypericum extract: specific T-type calcium channel blocker, and their use as T-type calcium channel targeted therapeutics
CA2485700A1 (en) * 2002-05-14 2003-11-20 J-Oil Mills, Inc. Body taste improver comprising long-chain highly unsaturated fatty acid and/or ester thereof and vegetable fat composition containing the same
AU2004255070B2 (en) * 2003-07-09 2009-06-25 J-Oil Mills, Inc. Full-bodied taste enhancer containing product of decomposition of long-chain highly unsaturated fatty acid or containing extract therefrom
TW201119585A (en) * 2003-11-12 2011-06-16 J Oil Mills Inc Body taste improver comprising long-chain highly unsaturated fatty acid and/or its ester
TW200526131A (en) * 2003-11-12 2005-08-16 J Oil Mills Inc Method of application of body taste enhancer comprising long-chain highly unsaturated fatty acid and/or its ester
JP5023322B2 (ja) * 2006-06-08 2012-09-12 国立大学法人高知大学 縮合多環化合物の製造方法
EP2046314A4 (en) * 2006-08-03 2009-12-30 Hy Biopharma Inc POLYCYCLIC DIANTHRAQUINONES AS INHIBITORS OF INFLAMMATORY CYTOKINES
EP2477957A4 (en) 2009-09-15 2013-07-03 Hy Biopharma Inc PROCESS FOR PREPARING HYPERICIN
CN103274920B (zh) * 2013-06-14 2014-12-17 西北农林科技大学 一种单色光引发高效合成金丝桃素的方法
CN104193610B (zh) * 2014-08-05 2015-12-02 中南大学 金丝桃素的合成方法
CA3016618C (en) * 2016-03-01 2023-12-19 Soligenix, Inc. Systems and methods for producing synthetic hypericin
US10053413B2 (en) * 2016-03-01 2018-08-21 Soligenix, Inc. Systems and methods for producing synthetic hypericin
CN108997104A (zh) * 2018-09-18 2018-12-14 湖北博瑞生物科技股份有限公司 一种原金丝桃素的合成方法
FR3111640B1 (fr) 2020-06-22 2022-07-22 Total Marketing Services Composition aqueuse pour la lubrification des systèmes mécaniques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1935721A (en) * 1928-12-01 1933-11-21 Gen Aniline Works Inc Manufacture of nitrogenous compounds derived from perylene quinone
US2707704A (en) * 1951-09-29 1955-05-03 Schenley Ind Inc Process for the preparation of hypericin
IL92315A (he) * 1989-11-15 1996-12-05 Yeda Res & Dev הכנת היפריצין מאמודין אנתרון

Also Published As

Publication number Publication date
DE69016620D1 (de) 1995-03-16
CA2029993C (en) 2001-01-16
EP0432496A3 (en) 1991-10-23
JPH03220155A (ja) 1991-09-27
ES2070244T3 (es) 1995-06-01
JP2896224B2 (ja) 1999-05-31
DK0432496T3 (da) 1995-06-26
ATE117978T1 (de) 1995-02-15
AU6665290A (en) 1991-05-23
IL92315A0 (en) 1990-07-26
EP0432496A2 (en) 1991-06-19
DE69016620T2 (de) 1995-05-24
US5120412A (en) 1992-06-09
EP0432496B1 (en) 1995-02-01
CA2029993A1 (en) 1991-05-16
GR3015919T3 (en) 1995-07-31
AU629066B2 (en) 1992-09-24

Similar Documents

Publication Publication Date Title
US5120412A (en) Preparation of hypericin
Wulff et al. Cycloadditions and annulations of transition metal carbene complexes
Gladysz et al. One-flask preparation of analytically pure dipotassium tetracarbonylferrate
Khurana et al. Deoxygenation of sulfoxides and selenoxides with nickel boride
Critchlow et al. The oxidation of some pyrogallol and purpurogallin derivatives
Cannon et al. The quinones of Nepenthes rafflesiana. The crystal structure of 2, 5-dihydroxy-3, 8-dimethoxy-7-methylnaphtho-1, 4-quinone (nepenthone-e) and a synthesis of 2, 5-dihydroxy-3-methoxy-7-methylnaphtho-1, 4-quinone (nepenthone-c)
US20120245392A1 (en) Methods for preparing hypericin
House et al. Use of dipolar aprotic solvents to alter the chemoselectivity of lithium dimethylcuprate
JPS60199900A (ja) テイコプラニン因子ａ↓２成分１をテイコプラニン因子ａ↓２成分３に転化する方法
Ishihara et al. Photochemistry of 5-bromouracil in aqueous solution
Gruszecka-Kowalik et al. An improved synthesis of hypericin and related compounds
Miki et al. An Improved Synthesis of Estrogens.
Kono et al. Studies on the host-specific pathotoxins produced by Helminthosporium maydis, race T
Axelrod et al. Biosynthesis and Characterization of 11β-Hydroxytestosterone1
Nelson et al. Steroidal Hormone Analogs. V. The Reaction of Cholestane-3-one with Diazomethane1
Munk et al. Quinoxaline Studies. IV. The Preparation of dl-2, 6-Dimethyl-1, 2, 3, 4-tetrahydroquinoxaline and dl-2, 7-Dimethyl-1, 2, 3, 4-tetrahydroquinoxaline
Djerassi et al. Optical Rotatory Dispersion Studies. LIX. 1 The Octant Rule and Deuterium. Synthesis of 3-Deuteriocyclopentanone2
Nagarajan et al. A sigmatropic rearrangement involving dimethyl sulfoxide during an oxidation of a carbohydrate derivative
Budzikiewicz et al. Dienone-Phenol Rearrangement of 2-Phenyl-o-quinol-acetate
Uchiyama et al. Synthetic Studies on Dehydrorotenone
CN116983264B (zh) 一种二氢大麻二酚二苯甲酸酯的包埋体系及其制备方法和应用
Zarebska et al. Radio-products of thymine in the presence of ethanol
US3819726A (en) Preparation of urushiol from poison ivy or poison oak
Radhakrishna et al. A SIMPLE REDUCTION OF ARALKYL KETONES TO ALCOHOLS
JPS62281831A (ja) ポリプレノイド型化合物の製造法

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void