IL92289A0 - 1-aminoalkyl-3-oxysubstituted 4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepine-2-ones,a process for their preparation and pharmaceutical compositions containing them - Google Patents

1-aminoalkyl-3-oxysubstituted 4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepine-2-ones,a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL92289A0
IL92289A0 IL92289A IL9228989A IL92289A0 IL 92289 A0 IL92289 A0 IL 92289A0 IL 92289 A IL92289 A IL 92289A IL 9228989 A IL9228989 A IL 9228989A IL 92289 A0 IL92289 A0 IL 92289A0
Authority
IL
Israel
Prior art keywords
oxysubstituted
benzodiazepine
aminoalkyl
tetrahydro
aryl
Prior art date
Application number
IL92289A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL92289A0 publication Critical patent/IL92289A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL92289A 1988-11-14 1989-11-13 1-aminoalkyl-3-oxysubstituted 4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepine-2-ones,a process for their preparation and pharmaceutical compositions containing them IL92289A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/270,335 US4908360A (en) 1988-11-14 1988-11-14 1-aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2H-1,3-benzodiazepine-2-ones

Publications (1)

Publication Number Publication Date
IL92289A0 true IL92289A0 (en) 1990-07-26

Family

ID=23030908

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92289A IL92289A0 (en) 1988-11-14 1989-11-13 1-aminoalkyl-3-oxysubstituted 4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepine-2-ones,a process for their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4908360A (ko)
EP (1) EP0369334A3 (ko)
JP (1) JPH02188572A (ko)
KR (1) KR900007811A (ko)
AU (1) AU623448B2 (ko)
CA (1) CA2002774A1 (ko)
DK (1) DK568289A (ko)
FI (1) FI895370A0 (ko)
HU (1) HU203737B (ko)
IL (1) IL92289A0 (ko)
NO (1) NO894516L (ko)
NZ (1) NZ231370A (ko)
PT (1) PT92295A (ko)
ZA (1) ZA898638B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0914605B1 (en) 1996-07-25 2007-05-30 Biogen Idec MA Inc. Molecular model for vla-4 inhibitors
US6686350B1 (en) * 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
EP1741428A3 (en) 1999-08-13 2007-05-09 Biogen Idec MA, Inc. Cell adhesion inhibitors
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474090A (en) * 1966-12-22 1969-10-21 American Cyanamid Co 3-aminoalkyl-1,3-benzodiazepin-2-ones
US4504680A (en) * 1978-10-05 1985-03-12 Hoechst-Roussel Pharmaceuticals Inc. 4-Phenyl-1,3-benzodiazepines
US4309424A (en) * 1978-10-05 1982-01-05 Hoechst-Roussel Pharmaceuticals Incorporated 4-Phenyl-1,3-benzodiazepines
US4469889A (en) * 1978-10-05 1984-09-04 Hoechst-Roussel Pharmaceuticals, Incorporated 2-(2-Nitrophenyl)-1-phenylethanone oxime acetates
US4822914A (en) * 1978-10-05 1989-04-18 Hoechst-Roussel Pharmaceuticals, Inc. 2-amino-N-methyl-α-phenyl-phenethylamines
US4459231A (en) * 1979-11-05 1984-07-10 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4462933A (en) * 1979-11-05 1984-07-31 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4459230A (en) * 1979-11-05 1984-07-10 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4409145A (en) * 1979-11-05 1983-10-11 Hoechst-Roussel Pharmaceuticals, Inc. Process for preparing 4-phenyl-1,3-benzodiazepines
US4709093A (en) * 1981-05-28 1987-11-24 Hoechst-Roussel Pharmaceuticals Inc. Method for the preparation of 4-phenyl-1,3-benzodiazepines and precursors thereof
US4374067A (en) * 1981-12-23 1983-02-15 Hoechst-Roussel Pharmaceuticals, Inc. Intermediates for the preparation of 4-phenyl-1,3-benzodiazepins and methods for preparing the intermediates
US4461728A (en) * 1981-12-23 1984-07-24 Hoechst Roussel Pharmaceuticals Inc. Preparation of 4-phenyl-1,3-benzodiazepins
HU191702B (en) * 1984-06-27 1987-03-30 Gyogyszerkutato Intezet New process for preparing 1-aryl-5 h-2,3-benzodiazepines
CA1271747C (en) * 1985-06-12 1990-07-17 BENZAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
PT92295A (pt) 1990-05-31
AU4458489A (en) 1990-05-17
AU623448B2 (en) 1992-05-14
US4908360A (en) 1990-03-13
JPH02188572A (ja) 1990-07-24
NO894516D0 (no) 1989-11-13
ZA898638B (en) 1990-08-29
NZ231370A (en) 1992-03-26
EP0369334A3 (en) 1990-12-12
HU895896D0 (en) 1990-02-28
DK568289D0 (da) 1989-11-13
DK568289A (da) 1990-05-15
FI895370A0 (fi) 1989-11-10
KR900007811A (ko) 1990-06-02
NO894516L (no) 1990-05-15
CA2002774A1 (en) 1990-05-14
EP0369334A2 (en) 1990-05-23
HUT52071A (en) 1990-06-28
HU203737B (en) 1991-09-30

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