DK568289A - 1-aminoalkyl-3-oxy-substituerede-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-oner, deres fremstilling og anvendelse som laegemidler - Google Patents

1-aminoalkyl-3-oxy-substituerede-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-oner, deres fremstilling og anvendelse som laegemidler

Info

Publication number
DK568289A
DK568289A DK568289A DK568289A DK568289A DK 568289 A DK568289 A DK 568289A DK 568289 A DK568289 A DK 568289A DK 568289 A DK568289 A DK 568289A DK 568289 A DK568289 A DK 568289A
Authority
DK
Denmark
Prior art keywords
oner
benzodiazepin
aminoalkyl
tetrahydro
oxy
Prior art date
Application number
DK568289A
Other languages
English (en)
Other versions
DK568289D0 (da
Inventor
Lawrence Leo Martin
Joseph Francis Payack
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK568289D0 publication Critical patent/DK568289D0/da
Publication of DK568289A publication Critical patent/DK568289A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK568289A 1988-11-14 1989-11-13 1-aminoalkyl-3-oxy-substituerede-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-oner, deres fremstilling og anvendelse som laegemidler DK568289A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/270,335 US4908360A (en) 1988-11-14 1988-11-14 1-aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2H-1,3-benzodiazepine-2-ones

Publications (2)

Publication Number Publication Date
DK568289D0 DK568289D0 (da) 1989-11-13
DK568289A true DK568289A (da) 1990-05-15

Family

ID=23030908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK568289A DK568289A (da) 1988-11-14 1989-11-13 1-aminoalkyl-3-oxy-substituerede-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-oner, deres fremstilling og anvendelse som laegemidler

Country Status (14)

Country Link
US (1) US4908360A (da)
EP (1) EP0369334A3 (da)
JP (1) JPH02188572A (da)
KR (1) KR900007811A (da)
AU (1) AU623448B2 (da)
CA (1) CA2002774A1 (da)
DK (1) DK568289A (da)
FI (1) FI895370A0 (da)
HU (1) HU203737B (da)
IL (1) IL92289A0 (da)
NO (1) NO894516L (da)
NZ (1) NZ231370A (da)
PT (1) PT92295A (da)
ZA (1) ZA898638B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686350B1 (en) * 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
DK0914605T3 (da) 1996-07-25 2007-09-10 Biogen Idec Inc Molekylemodel for VLA-4-inhibitorer
PL354063A1 (en) 1999-08-13 2003-12-15 Biogen, Inc.Biogen, Inc. Cell adhesion inhibitors
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474090A (en) * 1966-12-22 1969-10-21 American Cyanamid Co 3-aminoalkyl-1,3-benzodiazepin-2-ones
US4309424A (en) * 1978-10-05 1982-01-05 Hoechst-Roussel Pharmaceuticals Incorporated 4-Phenyl-1,3-benzodiazepines
US4822914A (en) * 1978-10-05 1989-04-18 Hoechst-Roussel Pharmaceuticals, Inc. 2-amino-N-methyl-α-phenyl-phenethylamines
US4504680A (en) * 1978-10-05 1985-03-12 Hoechst-Roussel Pharmaceuticals Inc. 4-Phenyl-1,3-benzodiazepines
US4469889A (en) * 1978-10-05 1984-09-04 Hoechst-Roussel Pharmaceuticals, Incorporated 2-(2-Nitrophenyl)-1-phenylethanone oxime acetates
US4459231A (en) * 1979-11-05 1984-07-10 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4462933A (en) * 1979-11-05 1984-07-31 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4459230A (en) * 1979-11-05 1984-07-10 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4409145A (en) * 1979-11-05 1983-10-11 Hoechst-Roussel Pharmaceuticals, Inc. Process for preparing 4-phenyl-1,3-benzodiazepines
US4709093A (en) * 1981-05-28 1987-11-24 Hoechst-Roussel Pharmaceuticals Inc. Method for the preparation of 4-phenyl-1,3-benzodiazepines and precursors thereof
US4461728A (en) * 1981-12-23 1984-07-24 Hoechst Roussel Pharmaceuticals Inc. Preparation of 4-phenyl-1,3-benzodiazepins
US4374067A (en) * 1981-12-23 1983-02-15 Hoechst-Roussel Pharmaceuticals, Inc. Intermediates for the preparation of 4-phenyl-1,3-benzodiazepins and methods for preparing the intermediates
HU191702B (en) * 1984-06-27 1987-03-30 Gyogyszerkutato Intezet New process for preparing 1-aryl-5 h-2,3-benzodiazepines
CA1271747A (en) * 1985-06-12 1990-07-17 David M. Floyd Benzazepines derivatives

Also Published As

Publication number Publication date
HU203737B (en) 1991-09-30
EP0369334A2 (en) 1990-05-23
HUT52071A (en) 1990-06-28
KR900007811A (ko) 1990-06-02
DK568289D0 (da) 1989-11-13
IL92289A0 (en) 1990-07-26
NO894516D0 (no) 1989-11-13
AU623448B2 (en) 1992-05-14
HU895896D0 (en) 1990-02-28
FI895370A0 (fi) 1989-11-10
PT92295A (pt) 1990-05-31
ZA898638B (en) 1990-08-29
JPH02188572A (ja) 1990-07-24
US4908360A (en) 1990-03-13
NO894516L (no) 1990-05-15
NZ231370A (en) 1992-03-26
EP0369334A3 (en) 1990-12-12
AU4458489A (en) 1990-05-17
CA2002774A1 (en) 1990-05-14

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