IL90244A - Peptide-drug compositions, for buccal and nasal administration, containing :-aminoboronic acid derivatives - Google Patents

Peptide-drug compositions, for buccal and nasal administration, containing :-aminoboronic acid derivatives

Info

Publication number
IL90244A
IL90244A IL90244A IL9024489A IL90244A IL 90244 A IL90244 A IL 90244A IL 90244 A IL90244 A IL 90244A IL 9024489 A IL9024489 A IL 9024489A IL 90244 A IL90244 A IL 90244A
Authority
IL
Israel
Prior art keywords
buccal
peptide
acid derivatives
nasal administration
drug compositions
Prior art date
Application number
IL90244A
Other languages
English (en)
Other versions
IL90244A0 (en
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of IL90244A0 publication Critical patent/IL90244A0/xx
Publication of IL90244A publication Critical patent/IL90244A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL90244A 1988-05-11 1989-05-09 Peptide-drug compositions, for buccal and nasal administration, containing :-aminoboronic acid derivatives IL90244A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19269088A 1988-05-11 1988-05-11

Publications (2)

Publication Number Publication Date
IL90244A0 IL90244A0 (en) 1989-12-15
IL90244A true IL90244A (en) 1993-05-13

Family

ID=22710674

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90244A IL90244A (en) 1988-05-11 1989-05-09 Peptide-drug compositions, for buccal and nasal administration, containing :-aminoboronic acid derivatives

Country Status (13)

Country Link
EP (1) EP0341661A3 (xx)
JP (1) JPH01319428A (xx)
KR (1) KR900017581A (xx)
AU (1) AU616968B2 (xx)
DK (1) DK229089A (xx)
FI (1) FI892254A (xx)
HU (1) HUT51144A (xx)
IL (1) IL90244A (xx)
MY (1) MY104088A (xx)
NO (1) NO891926L (xx)
NZ (1) NZ229053A (xx)
PT (1) PT90519B (xx)
ZA (1) ZA893517B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2673376A1 (fr) * 1991-03-01 1992-09-04 Lefesvre Andre Composition pharmaceutique pour le traitement des tumeurs de kaposi.
HUT69785A (en) * 1991-12-18 1995-09-28 Pfizer Soybean protein or hydrolylates in pharmaceutical compositions to protect bioaltive peptides from enzymatic inactivation
US6153592A (en) * 1992-11-09 2000-11-28 Port Systems, Llc Enhancing the bioavailability of proteolytically labile therapeutic agents
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
EP1695712A3 (en) 2002-09-09 2008-01-09 Trigen Limited Oral formulations for the selective inhibition of thrombin comprising boronic acid species

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499082A (en) * 1983-12-05 1985-02-12 E. I. Du Pont De Nemours And Company α-Aminoboronic acid peptides
US4537773A (en) * 1983-12-05 1985-08-27 E. I. Du Pont De Nemours And Company α-Aminoboronic acid derivatives
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
DE3840452A1 (de) * 1988-12-01 1990-06-07 Hoechst Ag (beta)-amino-boronsaeure-derivate

Also Published As

Publication number Publication date
FI892254A (fi) 1989-11-12
KR900017581A (ko) 1990-12-19
NZ229053A (en) 1990-12-21
IL90244A0 (en) 1989-12-15
PT90519A (pt) 1989-11-30
JPH01319428A (ja) 1989-12-25
DK229089A (da) 1989-11-12
DK229089D0 (da) 1989-05-10
NO891926L (no) 1989-11-13
PT90519B (pt) 1994-10-31
MY104088A (en) 1993-11-30
FI892254A0 (fi) 1989-05-10
AU616968B2 (en) 1991-11-14
ZA893517B (en) 1991-01-30
NO891926D0 (no) 1989-05-11
HUT51144A (en) 1990-04-28
EP0341661A2 (en) 1989-11-15
AU3468289A (en) 1989-11-16
EP0341661A3 (en) 1991-05-02

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