IL89930A0 - Pharmaceutical compositions containing tumor necrosis factor - Google Patents
Pharmaceutical compositions containing tumor necrosis factorInfo
- Publication number
- IL89930A0 IL89930A0 IL89930A IL8993089A IL89930A0 IL 89930 A0 IL89930 A0 IL 89930A0 IL 89930 A IL89930 A IL 89930A IL 8993089 A IL8993089 A IL 8993089A IL 89930 A0 IL89930 A0 IL 89930A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- necrosis factor
- tumor necrosis
- containing tumor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/181,077 US5215743A (en) | 1988-04-13 | 1988-04-13 | Tumor necrosis factor formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
IL89930A0 true IL89930A0 (en) | 1989-12-15 |
Family
ID=22662812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL89930A IL89930A0 (en) | 1988-04-13 | 1989-04-12 | Pharmaceutical compositions containing tumor necrosis factor |
Country Status (8)
Country | Link |
---|---|
US (1) | US5215743A (fr) |
EP (1) | EP0423244B1 (fr) |
JP (1) | JPH03504721A (fr) |
AU (1) | AU3447389A (fr) |
DE (1) | DE68913537D1 (fr) |
ES (1) | ES2013667A6 (fr) |
IL (1) | IL89930A0 (fr) |
WO (1) | WO1989009610A1 (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002531A1 (fr) * | 1989-08-17 | 1991-03-07 | Peter Maccallum Cancer Institute | Procede de modulation de l'hemopoïese chez un mammifere |
WO1993000807A1 (fr) * | 1991-07-03 | 1993-01-21 | Cryolife, Inc. | Procede de stabilisation de biomateriaux |
FR2684878B1 (fr) * | 1991-12-12 | 1994-02-11 | Roussel Uclaf | Composition pharmaceutique stabilisee d'il2 humaine recombinante non glycosylee sous forme reduite et son procede de preparation. |
IT1250075B (it) * | 1991-12-18 | 1995-03-30 | Serono Cesare Ist Ricerca | Composizioni farmaceutiche contenenti gonadotropine. |
US20020031563A1 (en) * | 1992-09-30 | 2002-03-14 | Hodge Thomas W. | Method of inhibiting tumor necrosis factor |
JPH0776527A (ja) * | 1993-06-28 | 1995-03-20 | Hayashibara Biochem Lab Inc | 半固形製剤とその製造方法 |
US6270757B1 (en) * | 1994-04-21 | 2001-08-07 | Genetics Institute, Inc. | Formulations for IL-11 |
RU2065307C1 (ru) * | 1994-12-13 | 1996-08-20 | Александр Васильевич Тихонов | Способ лечения первичного рака печени и набор для лечения первичного рака печени |
JP2000510813A (ja) * | 1995-02-06 | 2000-08-22 | ジェネテイックス・インスティテュート・インコーポレイテッド | Il−12用処方 |
US6540993B1 (en) | 1995-06-27 | 2003-04-01 | Wyeth | Method of treating inflammatory bowel disease using a topical formulation of IL-11 |
US6126933A (en) * | 1995-06-27 | 2000-10-03 | Genetics Institute | Methods of treating inflammatory bowel diseases by administering IL-11 |
US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
AUPO066096A0 (en) * | 1996-06-26 | 1996-07-18 | Peptide Delivery Systems Pty Ltd | Oral delivery of peptides |
US6991790B1 (en) * | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
WO1999018119A1 (fr) * | 1997-10-03 | 1999-04-15 | Shionogi & Co., Ltd. | Procede de lyophilisation de proteines |
US6617171B2 (en) * | 1998-02-27 | 2003-09-09 | The General Hospital Corporation | Methods for diagnosing and treating autoimmune disease |
US20030187196A1 (en) * | 1998-12-30 | 2003-10-02 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US6599710B1 (en) | 1999-03-10 | 2003-07-29 | The General Hospital Corporation | Treatment of autoimmune disease |
US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
US6875432B2 (en) * | 2000-10-12 | 2005-04-05 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
KR20050042032A (ko) * | 2001-11-02 | 2005-05-04 | 세키스이가가쿠 고교가부시키가이샤 | 사이토카인 유도 재료 및 사이토카인 유도 용구 |
US7582313B2 (en) | 2002-06-27 | 2009-09-01 | The General Hospital Corporation | Methods of organ regeneration using Hox 11-expressing pluripotent cells |
US7628988B2 (en) * | 2002-06-27 | 2009-12-08 | The General Hospital Corporation | Methods and compositions for treating type 1 diabetes |
AU2003290948A1 (en) * | 2002-11-15 | 2004-06-15 | The General Hospital Corporation | Screening methods to identify treatments for autoimmune disease |
WO2004050683A2 (fr) * | 2002-12-02 | 2004-06-17 | Abgenix, Inc. | Anticorps agissant sur le facteur de necrose des tumeurs (tnf) et leurs utilisation |
PL1610820T5 (pl) | 2003-04-04 | 2014-01-31 | Genentech Inc | Preparaty zawierające wysokoskoncentrowane przeciwciała i białka |
US20050158303A1 (en) * | 2003-04-04 | 2005-07-21 | Genentech, Inc. | Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations |
EP2266600B1 (fr) * | 2004-07-26 | 2014-09-10 | Merz Pharma GmbH & Co. KGaA | Composition thérapeutique à base de neurotoxine botulique |
US20080102054A1 (en) * | 2005-01-18 | 2008-05-01 | Faustman Denise L | Compositions Containing Agm Cells And Methods Of Use Thereof |
US8137677B2 (en) * | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
WO2008101179A2 (fr) * | 2007-02-16 | 2008-08-21 | Wyeth | Utilisation de saccharose pour supprimer une agrégation de protéines provoquée par du mannitol |
RU2011140498A (ru) * | 2009-03-06 | 2013-04-20 | Дженентек, Инк. | Препарат антител |
EP3738605A1 (fr) | 2012-09-10 | 2020-11-18 | Xencor, Inc. | Procédés de traitement de maladies neurologiques |
CA2889271A1 (fr) | 2012-10-26 | 2014-05-01 | Lupin Atlantis Holdings Sa | Composition pharmaceutique stable d'une proteine hybride tnfr:fc |
DK2953634T3 (da) | 2013-02-07 | 2021-08-30 | Massachusetts Gen Hospital | Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler |
CN104274827B (zh) | 2013-07-01 | 2020-07-14 | 上海贺普药业股份有限公司 | 贺普拉肽的制剂 |
TWI593967B (zh) * | 2014-05-01 | 2017-08-01 | 高雄醫學大學 | 二級抗體所辨識之抗原決定位及其用途 |
CN107849142B (zh) | 2015-05-15 | 2022-04-26 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族抗体 |
WO2016201409A1 (fr) | 2015-06-12 | 2016-12-15 | Georgia State University Research Foundation | Compositions et méthodes pour traiter la tolérance aux opioïdes |
EP3355914B1 (fr) | 2015-09-29 | 2024-03-06 | The General Hospital Corporation | Une composition comprenant bcg pour réduire le cholesterol. |
KR20240095471A (ko) | 2016-05-13 | 2024-06-25 | 더 제너럴 하스피탈 코포레이션 | 길항성 항-종양 괴사 인자 수용체 슈퍼패밀리 항체 |
CN106620656A (zh) * | 2017-03-03 | 2017-05-10 | 上海唯科生物制药有限公司 | 一种肿瘤坏死因子舌下给药制剂及其制备方法 |
CN106729633A (zh) * | 2017-03-03 | 2017-05-31 | 上海唯科生物制药有限公司 | 一种肿瘤坏死因子直肠给药制剂及其制备方法 |
CN111110638B (zh) * | 2020-01-10 | 2022-10-14 | 广州市丹蓝生物科技有限公司 | 一种偶联有蛋白的微球冻干制剂及其制备方法、保存方式 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4447355A (en) * | 1982-04-07 | 1984-05-08 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for stabilizing a tumor necrosis factor and a stable aqueous solution or powder containing the same |
US4457916A (en) * | 1982-08-31 | 1984-07-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same |
US4797388A (en) * | 1984-05-21 | 1989-01-10 | Cetus Corporation | Pharmaceutical compositions with galactitol as carrier |
JPS60258125A (ja) * | 1984-06-06 | 1985-12-20 | Hayashibara Biochem Lab Inc | 蛋白性生理活性物質を含有する水溶性乾燥物 |
US4650674A (en) * | 1984-07-05 | 1987-03-17 | Genentech, Inc. | Synergistic cytotoxic composition |
US4677063A (en) * | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
US4677064A (en) * | 1984-11-09 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
JPH0710342B2 (ja) * | 1985-12-26 | 1995-02-08 | 株式会社林原生物化学研究所 | 無水アルドヘキソ−スによる含水物の脱水方法 |
US4762857A (en) * | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
-
1988
- 1988-04-13 US US07/181,077 patent/US5215743A/en not_active Expired - Fee Related
-
1989
- 1989-03-22 JP JP1504712A patent/JPH03504721A/ja active Pending
- 1989-03-22 EP EP89909946A patent/EP0423244B1/fr not_active Expired - Lifetime
- 1989-03-22 WO PCT/US1989/001226 patent/WO1989009610A1/fr active IP Right Grant
- 1989-03-22 AU AU34473/89A patent/AU3447389A/en not_active Abandoned
- 1989-03-22 DE DE89909946T patent/DE68913537D1/de not_active Expired - Lifetime
- 1989-04-12 IL IL89930A patent/IL89930A0/xx unknown
- 1989-04-13 ES ES8901300A patent/ES2013667A6/es not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE68913537D1 (de) | 1994-04-07 |
US5215743A (en) | 1993-06-01 |
EP0423244A1 (fr) | 1991-04-24 |
AU3447389A (en) | 1989-11-03 |
JPH03504721A (ja) | 1991-10-17 |
EP0423244B1 (fr) | 1994-03-02 |
WO1989009610A1 (fr) | 1989-10-19 |
ES2013667A6 (es) | 1990-05-16 |
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