IL84295A - Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes - Google Patents
Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranesInfo
- Publication number
- IL84295A IL84295A IL84295A IL8429587A IL84295A IL 84295 A IL84295 A IL 84295A IL 84295 A IL84295 A IL 84295A IL 8429587 A IL8429587 A IL 8429587A IL 84295 A IL84295 A IL 84295A
- Authority
- IL
- Israel
- Prior art keywords
- measurement
- changes
- cell growth
- growth rate
- cyanine dye
- Prior art date
Links
- 230000010261 cell growth Effects 0.000 title 1
- 210000000170 cell membrane Anatomy 0.000 title 1
- 238000005259 measurement Methods 0.000 title 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/925,429 US4859584A (en) | 1986-10-31 | 1986-10-31 | Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL84295A0 IL84295A0 (en) | 1988-03-31 |
| IL84295A true IL84295A (en) | 1991-12-15 |
Family
ID=25451718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL84295A IL84295A (en) | 1986-10-31 | 1987-10-27 | Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4859584A (da) |
| EP (1) | EP0266196A3 (da) |
| JP (1) | JPS63122955A (da) |
| KR (1) | KR880005457A (da) |
| CN (1) | CN1014276B (da) |
| AU (1) | AU607944B2 (da) |
| CA (1) | CA1294544C (da) |
| DK (1) | DK560587A (da) |
| IE (1) | IE872873L (da) |
| IL (1) | IL84295A (da) |
| PH (1) | PH25250A (da) |
| PT (1) | PT86029B (da) |
| ZA (1) | ZA878115B (da) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3038339B2 (ja) * | 1988-05-02 | 2000-05-08 | ザイナクシス・テクノロジーズ・インコーポレーテッド | バイオ粒子の表面膜に対してバイオアフェクティング物質を結合する化合物 |
| US5169788A (en) * | 1989-06-09 | 1992-12-08 | New England Deaconess Hospital Corporation | Methods of measuring membrane potential using j-aggregate forming dyes |
| JP2824917B2 (ja) * | 1989-08-30 | 1998-11-18 | 株式会社林原生物化学研究所 | 抗腫瘍剤 |
| US5164301A (en) * | 1990-06-22 | 1992-11-17 | Difco Laboratories | Process and kit for detecting microbial metabolism |
| JP3070968B2 (ja) * | 1991-05-14 | 2000-07-31 | シスメックス株式会社 | 尿中の細胞分析用試薬及び方法 |
| ATE171543T1 (de) * | 1991-07-16 | 1998-10-15 | Transmed Biotech Inc | Verfahren und zusammensetzungen für die gleichzeitige analyse einer vielzahl von analyten |
| US5306624A (en) * | 1992-09-17 | 1994-04-26 | Packard Instrument Co., Inc. | Process of quantifying cell number |
| US5995645A (en) * | 1993-08-18 | 1999-11-30 | Applied Spectral Imaging Ltd. | Method of cancer cell detection |
| DE19539409C2 (de) * | 1995-10-11 | 1999-02-18 | Diagnostikforschung Inst | Kontrastmittel für die Nahinfrarot-Diagnostik |
| US6004536A (en) * | 1995-11-14 | 1999-12-21 | Molecular Probes, Inc. | Lipophilic cyanine dyes with enchanced aqueous solubilty |
| US5804389A (en) * | 1995-12-29 | 1998-09-08 | Phanos Technologies, Inc. | Method for detecting abnormal epithelial cell shedding |
| DE19603033A1 (de) | 1996-01-19 | 1997-07-24 | Schering Ag | Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
| US5989835A (en) * | 1997-02-27 | 1999-11-23 | Cellomics, Inc. | System for cell-based screening |
| US6008010A (en) | 1996-11-01 | 1999-12-28 | University Of Pittsburgh | Method and apparatus for holding cells |
| KR100502440B1 (ko) * | 1997-02-04 | 2005-07-20 | 파노스 테크놀로지즈 인코포레이티드 | 비정상적 상피세포의 박리를 측정하는 방법 |
| WO1998038490A1 (en) | 1997-02-27 | 1998-09-03 | Cellomics, Inc. | A system for cell-based screening |
| US7117098B1 (en) | 1997-02-27 | 2006-10-03 | Cellomics, Inc. | Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm |
| US6727071B1 (en) | 1997-02-27 | 2004-04-27 | Cellomics, Inc. | System for cell-based screening |
| JP2001518934A (ja) * | 1997-03-25 | 2001-10-16 | ラスター，モーリス | 移植部位としての骨髄 |
| WO2000018951A1 (en) | 1998-09-25 | 2000-04-06 | Xoma Technology Ltd. | Identification of novel antimicrobial agents using membrane potential indicator dyes |
| US6986993B1 (en) | 1999-08-05 | 2006-01-17 | Cellomics, Inc. | System for cell-based screening |
| US6351663B1 (en) | 1999-09-10 | 2002-02-26 | Akorn, Inc. | Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation |
| US6944493B2 (en) * | 1999-09-10 | 2005-09-13 | Akora, Inc. | Indocyanine green (ICG) compositions and related methods of use |
| US6673568B1 (en) * | 1999-10-25 | 2004-01-06 | Genprime, Inc. | Method and apparatus for prokaryotic and eukaryotic cell quantitation |
| US6787302B2 (en) * | 1999-10-25 | 2004-09-07 | Genprime, Inc. | Method and apparatus for prokaryotic and eukaryotic cell quantitation |
| US6443976B1 (en) | 1999-11-30 | 2002-09-03 | Akorn, Inc. | Methods for treating conditions and illnesses associated with abnormal vasculature |
| AU2073801A (en) | 1999-12-09 | 2001-06-18 | Cellomics, Inc. | A system for cell-based screening |
| CN1427889B (zh) | 2000-01-11 | 2011-06-29 | 格林维尔医院系统公司 | 由抗原提呈细胞可获得的杂交细胞 |
| US20070212338A1 (en) * | 2000-01-11 | 2007-09-13 | Greenville Hospital System | Hybrid cells |
| US20090087450A1 (en) * | 2000-01-11 | 2009-04-02 | Greenville Hospital System | Combination therapy of hybrid cells with BCG injection for treating Cancer Patients |
| AU4542401A (en) * | 2000-03-03 | 2001-09-17 | Phanos Tech Inc | Fluorescent membrane intercalating probes and methods for their use |
| US6689391B2 (en) | 2001-03-30 | 2004-02-10 | Council Of Scientific & Industrial Research | Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses |
| WO2002079391A2 (en) * | 2001-04-02 | 2002-10-10 | Cytoprint, Inc. | Methods and apparatus for discovering, identifying and comparing biological activity mechanisms |
| US7776529B2 (en) | 2003-12-05 | 2010-08-17 | Life Technologies Corporation | Methine-substituted cyanine dye compounds |
| US7399608B2 (en) | 2003-12-16 | 2008-07-15 | Kimberly-Clark Worldwide, Inc. | Microbial detection and quantification |
| US7282349B2 (en) | 2003-12-16 | 2007-10-16 | Kimberly-Clark Worldwide, Inc. | Solvatochromatic bacterial detection |
| CN101080498B (zh) * | 2003-12-16 | 2012-10-10 | 金伯利-克拉克环球有限公司 | 弹性物品上微生物污染的检测 |
| US7300770B2 (en) | 2004-12-16 | 2007-11-27 | Kimberly-Clark Worldwide, Inc. | Detection of microbe contamination on elastomeric articles |
| EP1781337A4 (en) * | 2004-08-05 | 2010-06-23 | Univ Leland Stanford Junior | METHOD AND COMPOSITIONS FOR CELL ACTIVATION |
| MX2007007122A (es) * | 2004-12-16 | 2009-02-18 | Kimberly Clark Co | Deteccion y cuantificacion microbial. |
| JP5306811B2 (ja) | 2005-05-11 | 2013-10-02 | ライフ テクノロジーズ コーポレーション | ２本鎖ｄｎａへの高い選択性を有する蛍光化学物質及びそれらの使用 |
| AU2005234696B2 (en) | 2005-11-18 | 2012-02-16 | Phanos Technologies, Inc. | Fluorescent membrane intercalating probes and methods for their use |
| US7727513B2 (en) | 2005-12-15 | 2010-06-01 | Kimberly-Clark Worldwide, Inc. | Method for screening for bacterial conjunctivitis |
| CN101518528B (zh) * | 2008-02-29 | 2014-02-26 | 史春梦 | 一组碳花青染料类的近红外荧光化合物的用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168206A (en) * | 1977-05-02 | 1979-09-18 | Philadelphia College Of Osteopathic Medicine | Impregnated disk method for testing antifungal susceptibility |
| US4343782A (en) * | 1978-04-20 | 1982-08-10 | Shapiro Howard M | Cytological assay procedure |
| US4225669A (en) * | 1979-04-27 | 1980-09-30 | Melnick Joseph L | Staining and analysis of bacteria |
| US4232121A (en) * | 1978-09-25 | 1980-11-04 | Eastman Kodak Company | Process for selecting methine dyes which inhibit cell growth |
| US4424201A (en) * | 1978-11-28 | 1984-01-03 | Rockefeller University | Employment of a mereyanine dye for the detection of malignant leukocytic cells |
| EP0054001B1 (fr) * | 1980-12-05 | 1985-04-03 | Battelle Memorial Institute | Méthode pour observer le développement de micro-organismes |
| US4423145A (en) * | 1981-05-07 | 1983-12-27 | Stampfer Martha R | Enhanced growth medium and method for culturing human mammary epithelial cells |
| US4559299A (en) * | 1983-02-04 | 1985-12-17 | Brown University Research Foundation Inc. | Cytotoxicity assays in cell culturing devices |
| US4783401A (en) * | 1986-10-31 | 1988-11-08 | Smithkline Beckman Corporation | Viable cell labelling |
-
1986
- 1986-10-31 US US06/925,429 patent/US4859584A/en not_active Expired - Lifetime
-
1987
- 1987-10-26 CA CA000550188A patent/CA1294544C/en not_active Expired - Lifetime
- 1987-10-26 DK DK560587A patent/DK560587A/da not_active Application Discontinuation
- 1987-10-27 IE IE872873A patent/IE872873L/xx unknown
- 1987-10-27 PH PH35987A patent/PH25250A/en unknown
- 1987-10-27 IL IL84295A patent/IL84295A/xx not_active IP Right Cessation
- 1987-10-28 AU AU80402/87A patent/AU607944B2/en not_active Ceased
- 1987-10-29 PT PT86029A patent/PT86029B/pt not_active IP Right Cessation
- 1987-10-29 ZA ZA878115A patent/ZA878115B/xx unknown
- 1987-10-29 EP EP87309556A patent/EP0266196A3/en not_active Withdrawn
- 1987-10-30 JP JP62277258A patent/JPS63122955A/ja active Pending
- 1987-10-30 KR KR870012049A patent/KR880005457A/ko not_active Withdrawn
- 1987-10-30 CN CN87107220A patent/CN1014276B/zh not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4859584A (en) | 1989-08-22 |
| PT86029B (pt) | 1990-08-31 |
| AU607944B2 (en) | 1991-03-21 |
| DK560587D0 (da) | 1987-10-26 |
| IL84295A0 (en) | 1988-03-31 |
| ZA878115B (en) | 1988-09-28 |
| KR880005457A (ko) | 1988-06-29 |
| EP0266196A3 (en) | 1990-05-23 |
| CA1294544C (en) | 1992-01-21 |
| AU8040287A (en) | 1988-05-05 |
| DK560587A (da) | 1988-05-01 |
| JPS63122955A (ja) | 1988-05-26 |
| PT86029A (en) | 1987-11-01 |
| PH25250A (en) | 1991-03-27 |
| CN87107220A (zh) | 1988-05-11 |
| CN1014276B (zh) | 1991-10-09 |
| IE872873L (en) | 1988-04-30 |
| EP0266196A2 (en) | 1988-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9K | Patent not in force due to non-payment of renewal fees |