IL83944A - Pharmaceutical compositions containing 2), 3)-dideoxcytidin-2) ene (2), 3)-dideoxy-2)), 3)-didehydrocytidine) for treating patients infected with retroviruses - Google Patents

Pharmaceutical compositions containing 2), 3)-dideoxcytidin-2) ene (2), 3)-dideoxy-2)), 3)-didehydrocytidine) for treating patients infected with retroviruses

Info

Publication number
IL83944A
IL83944A IL83944A IL8394487A IL83944A IL 83944 A IL83944 A IL 83944A IL 83944 A IL83944 A IL 83944A IL 8394487 A IL8394487 A IL 8394487A IL 83944 A IL83944 A IL 83944A
Authority
IL
Israel
Prior art keywords
ene
dideoxcytidin
didehydrocytidine
dideoxy
retroviruses
Prior art date
Application number
IL83944A
Other languages
English (en)
Other versions
IL83944A0 (en
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Publication of IL83944A0 publication Critical patent/IL83944A0/xx
Publication of IL83944A publication Critical patent/IL83944A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL83944A 1986-09-24 1987-09-18 Pharmaceutical compositions containing 2), 3)-dideoxcytidin-2) ene (2), 3)-dideoxy-2)), 3)-didehydrocytidine) for treating patients infected with retroviruses IL83944A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91120086A 1986-09-24 1986-09-24

Publications (2)

Publication Number Publication Date
IL83944A0 IL83944A0 (en) 1988-02-29
IL83944A true IL83944A (en) 1993-01-31

Family

ID=25429894

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83944A IL83944A (en) 1986-09-24 1987-09-18 Pharmaceutical compositions containing 2), 3)-dideoxcytidin-2) ene (2), 3)-dideoxy-2)), 3)-didehydrocytidine) for treating patients infected with retroviruses

Country Status (18)

Country Link
EP (1) EP0261595B1 (fr)
JP (2) JPH078796B2 (fr)
KR (1) KR960001372B1 (fr)
AT (1) ATE80039T1 (fr)
AU (1) AU596864B2 (fr)
CA (1) CA1304360C (fr)
DE (1) DE3781488T2 (fr)
DK (1) DK462687A (fr)
EG (1) EG18441A (fr)
ES (1) ES2052533T3 (fr)
FI (1) FI874166A (fr)
GR (1) GR3005870T3 (fr)
IE (1) IE62103B1 (fr)
IL (1) IL83944A (fr)
NZ (1) NZ221893A (fr)
PH (1) PH22990A (fr)
PT (1) PT85755B (fr)
ZA (1) ZA876411B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116822A (en) * 1986-10-24 1992-05-26 Stichting Rega Vzw Therapeutic application of dideoxycytidinene
JPS63107924A (ja) * 1986-10-25 1988-05-12 Yamasa Shoyu Co Ltd 抗レトロウイルス剤
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) * 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
JPH02152976A (ja) * 1988-05-06 1990-06-12 Bristol Myers Co 2´,3´―ジデヒドロ―2´,3´―ジデオキシヌクレオシドのプロドラッグ
SE8802687D0 (sv) * 1988-07-20 1988-07-20 Astra Ab Nucleoside derivatives
EP0355031A3 (fr) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Nucléosides pyrimidiniques substitués, leur procédé de préparation et médicaments les contenant
FI95269C (fi) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
GB2257363B (en) * 1991-01-30 1994-09-28 Wellcome Found Water dispersible tablets containing acyclovir
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides
MX9702927A (es) * 1994-10-24 1998-04-30 Genencor Int L-piranosilnucleosidos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
FR2528311B1 (fr) * 1982-06-14 1985-06-14 Synthelabo Compositions pharmaceutiques a base de xylosides et lyxosides de bases puriques et pyrimidiques
WO1987001283A1 (fr) * 1985-08-26 1987-03-12 United States Of America, Represented By The Unite Inhibition du caractere infectieux et de l'effet cytopathique du htlv-iii/lav in vitro par la 2',3'-dideoxycytidine
WO1987004929A1 (fr) * 1986-02-20 1987-08-27 Greer Sheldon B Composition et procede de traitement du sida et de certaines maladies s'y rapportant

Also Published As

Publication number Publication date
KR880003626A (ko) 1988-05-28
EP0261595A2 (fr) 1988-03-30
DK462687A (da) 1988-03-25
GR3005870T3 (fr) 1993-06-07
EG18441A (en) 1992-12-30
EP0261595A3 (en) 1990-01-24
PH22990A (en) 1989-02-24
PT85755B (pt) 1990-08-31
AU596864B2 (en) 1990-05-17
PT85755A (en) 1987-10-01
IL83944A0 (en) 1988-02-29
JPH078796B2 (ja) 1995-02-01
JPH0818986B2 (ja) 1996-02-28
NZ221893A (en) 1990-11-27
FI874166A0 (fi) 1987-09-23
ATE80039T1 (de) 1992-09-15
KR960001372B1 (ko) 1996-01-26
DE3781488D1 (de) 1992-10-08
EP0261595B1 (fr) 1992-09-02
CA1304360C (fr) 1992-06-30
JPS63146822A (ja) 1988-06-18
IE872562L (en) 1988-03-24
IE62103B1 (en) 1994-12-14
JPH07145058A (ja) 1995-06-06
AU7797787A (en) 1988-03-31
FI874166A (fi) 1988-03-25
ES2052533T3 (es) 1994-07-16
ZA876411B (en) 1988-03-18
DK462687D0 (da) 1987-09-04
DE3781488T2 (de) 1993-02-18

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Legal Events

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