ZA876411B - A substance or composition comprising 2',3'-dideoxycytidin-2'-ene(2',3'-dideoxy-2',3'-didehydrocytidine)for use in treating patients infected with retroviruses - Google Patents

A substance or composition comprising 2',3'-dideoxycytidin-2'-ene(2',3'-dideoxy-2',3'-didehydrocytidine)for use in treating patients infected with retroviruses

Info

Publication number
ZA876411B
ZA876411B ZA876411A ZA876411A ZA876411B ZA 876411 B ZA876411 B ZA 876411B ZA 876411 A ZA876411 A ZA 876411A ZA 876411 A ZA876411 A ZA 876411A ZA 876411 B ZA876411 B ZA 876411B
Authority
ZA
South Africa
Prior art keywords
dideoxycytidin
ene
didehydrocytidine
dideoxy
retroviruses
Prior art date
Application number
ZA876411A
Other languages
English (en)
Inventor
Lin Tai-Shun
H. Prusoff William
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Publication of ZA876411B publication Critical patent/ZA876411B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA876411A 1986-09-24 1987-08-27 A substance or composition comprising 2',3'-dideoxycytidin-2'-ene(2',3'-dideoxy-2',3'-didehydrocytidine)for use in treating patients infected with retroviruses ZA876411B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91120086A 1986-09-24 1986-09-24

Publications (1)

Publication Number Publication Date
ZA876411B true ZA876411B (en) 1988-03-18

Family

ID=25429894

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876411A ZA876411B (en) 1986-09-24 1987-08-27 A substance or composition comprising 2',3'-dideoxycytidin-2'-ene(2',3'-dideoxy-2',3'-didehydrocytidine)for use in treating patients infected with retroviruses

Country Status (18)

Country Link
EP (1) EP0261595B1 (xx)
JP (2) JPH078796B2 (xx)
KR (1) KR960001372B1 (xx)
AT (1) ATE80039T1 (xx)
AU (1) AU596864B2 (xx)
CA (1) CA1304360C (xx)
DE (1) DE3781488T2 (xx)
DK (1) DK462687A (xx)
EG (1) EG18441A (xx)
ES (1) ES2052533T3 (xx)
FI (1) FI874166A (xx)
GR (1) GR3005870T3 (xx)
IE (1) IE62103B1 (xx)
IL (1) IL83944A (xx)
NZ (1) NZ221893A (xx)
PH (1) PH22990A (xx)
PT (1) PT85755B (xx)
ZA (1) ZA876411B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116822A (en) * 1986-10-24 1992-05-26 Stichting Rega Vzw Therapeutic application of dideoxycytidinene
JPS63107924A (ja) * 1986-10-25 1988-05-12 Yamasa Shoyu Co Ltd 抗レトロウイルス剤
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) * 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
JPH02152976A (ja) * 1988-05-06 1990-06-12 Bristol Myers Co 2´,3´―ジデヒドロ―2´,3´―ジデオキシヌクレオシドのプロドラッグ
SE8802687D0 (sv) * 1988-07-20 1988-07-20 Astra Ab Nucleoside derivatives
EP0355031A3 (de) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Substituierte Pyrimidinnucleoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
FI95269C (fi) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
NL9220009A (nl) * 1991-01-30 1993-11-01 Wellcome Found In water-dispergeerbare tabletten.
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
ATE284894T1 (de) * 1994-10-24 2005-01-15 Genencor Int L-pyranosyl-nukleoside
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
FR2528311B1 (fr) * 1982-06-14 1985-06-14 Synthelabo Compositions pharmaceutiques a base de xylosides et lyxosides de bases puriques et pyrimidiques
JPS62501777A (ja) * 1985-08-26 1987-07-16 アメリカ合衆国 2′,3′―ジデオキシシチジンを含有する抗htlv―3/lav剤
WO1987004929A1 (en) * 1986-02-20 1987-08-27 Greer Sheldon B Composition for and method of treating aids and certain related diseases

Also Published As

Publication number Publication date
CA1304360C (en) 1992-06-30
EG18441A (en) 1992-12-30
DK462687A (da) 1988-03-25
PT85755B (pt) 1990-08-31
IE872562L (en) 1988-03-24
GR3005870T3 (xx) 1993-06-07
JPH07145058A (ja) 1995-06-06
FI874166A0 (fi) 1987-09-23
EP0261595A2 (en) 1988-03-30
IL83944A (en) 1993-01-31
AU7797787A (en) 1988-03-31
DE3781488D1 (de) 1992-10-08
JPH078796B2 (ja) 1995-02-01
FI874166A (fi) 1988-03-25
AU596864B2 (en) 1990-05-17
KR880003626A (ko) 1988-05-28
PH22990A (en) 1989-02-24
DK462687D0 (da) 1987-09-04
EP0261595A3 (en) 1990-01-24
IE62103B1 (en) 1994-12-14
JPH0818986B2 (ja) 1996-02-28
EP0261595B1 (en) 1992-09-02
IL83944A0 (en) 1988-02-29
ES2052533T3 (es) 1994-07-16
PT85755A (en) 1987-10-01
DE3781488T2 (de) 1993-02-18
ATE80039T1 (de) 1992-09-15
JPS63146822A (ja) 1988-06-18
KR960001372B1 (ko) 1996-01-26
NZ221893A (en) 1990-11-27

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