IL80459A - Water-soluble adduct of norfloxacin and nicotinic acid - Google Patents

Water-soluble adduct of norfloxacin and nicotinic acid

Info

Publication number
IL80459A
IL80459A IL80459A IL8045986A IL80459A IL 80459 A IL80459 A IL 80459A IL 80459 A IL80459 A IL 80459A IL 8045986 A IL8045986 A IL 8045986A IL 80459 A IL80459 A IL 80459A
Authority
IL
Israel
Prior art keywords
norfloxacin
water
nicotinic acid
soluble adduct
adduct
Prior art date
Application number
IL80459A
Other languages
English (en)
Other versions
IL80459A0 (en
Inventor
Simonovitch Haim
Original Assignee
Abic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abic Ltd filed Critical Abic Ltd
Priority to IL80459A priority Critical patent/IL80459A/xx
Publication of IL80459A0 publication Critical patent/IL80459A0/xx
Priority to US07/096,398 priority patent/US4792552A/en
Priority to AU78387/87A priority patent/AU597422C/en
Priority to ZA877149A priority patent/ZA877149B/xx
Priority to DK512187A priority patent/DK167530B1/da
Priority to JP62272898A priority patent/JPH0717609B2/ja
Priority to EP87309600A priority patent/EP0269278B1/en
Priority to ES87309600T priority patent/ES2039316T3/es
Priority to HU874880A priority patent/HU198472B/hu
Priority to AT87309600T priority patent/ATE74910T1/de
Priority to DE8787309600T priority patent/DE3778314D1/de
Priority to CA000550577A priority patent/CA1272487A/en
Publication of IL80459A publication Critical patent/IL80459A/xx
Priority to MX9203470A priority patent/MX9203470A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
IL80459A 1986-10-30 1986-10-30 Water-soluble adduct of norfloxacin and nicotinic acid IL80459A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IL80459A IL80459A (en) 1986-10-30 1986-10-30 Water-soluble adduct of norfloxacin and nicotinic acid
US07/096,398 US4792552A (en) 1986-10-30 1987-09-11 Water-soluble adduct of norfloxacin
AU78387/87A AU597422C (en) 1986-10-30 1987-09-14 A water soluble adduct of norfloxacin
ZA877149A ZA877149B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-10-30 1987-09-23
DK512187A DK167530B1 (da) 1986-10-30 1987-09-29 Nikotinsyre: norfloxacinaddukt, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat og vandig oploesning, som indeholder adduktet, og anvendelse af adduktet
JP62272898A JPH0717609B2 (ja) 1986-10-30 1987-10-28 ノルフロキサシンの水溶性付加物
CA000550577A CA1272487A (en) 1986-10-30 1987-10-29 Water-soluble adduct of norfloxacin
EP87309600A EP0269278B1 (en) 1986-10-30 1987-10-29 A water-soluble adduct of norfloxacin
ES87309600T ES2039316T3 (es) 1986-10-30 1987-10-29 Aducto de norfloxacina hidrosoluble.
HU874880A HU198472B (en) 1986-10-30 1987-10-29 Process for producing adduct comprising norfloxacin and pharmaceutical composition comprising such adduct
AT87309600T ATE74910T1 (de) 1986-10-30 1987-10-29 Wasserloesliches norfloxacinaddukt.
DE8787309600T DE3778314D1 (de) 1986-10-30 1987-10-29 Wasserloesliches norfloxacinaddukt.
MX9203470A MX9203470A (es) 1986-10-30 1992-06-26 Aducto soluble en agua de norfloxacin.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL80459A IL80459A (en) 1986-10-30 1986-10-30 Water-soluble adduct of norfloxacin and nicotinic acid

Publications (2)

Publication Number Publication Date
IL80459A0 IL80459A0 (en) 1987-01-30
IL80459A true IL80459A (en) 1991-04-15

Family

ID=11057240

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80459A IL80459A (en) 1986-10-30 1986-10-30 Water-soluble adduct of norfloxacin and nicotinic acid

Country Status (11)

Country Link
US (1) US4792552A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0269278B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0717609B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE74910T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1272487A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3778314D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK167530B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2039316T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU198472B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL80459A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA877149B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
US5225413A (en) * 1988-09-16 1993-07-06 Bayer-Aktiengesellschaft pH-neutral aqueous solutions of quinolone-carboxylic acids
US5360119A (en) * 1992-09-03 1994-11-01 Kyowa Kogyo Co., Ltd. Separator for removing foreign materials in granulated materials
US5373947A (en) * 1993-08-24 1994-12-20 Kyowa Kogyo Co., Ltd. Separator for removing foreign materials in granulated materials
ES2127036B1 (es) * 1994-03-21 1999-11-16 Ind Quimica Agropecuaria S A Aducto de norfloxacina soluble en agua.
US5942508A (en) * 1997-02-04 1999-08-24 Senju Pharmaceutical Co., Ltd. Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
JP4707201B2 (ja) * 1997-02-04 2011-06-22 千寿製薬株式会社 ピリドンカルボン酸の可溶化方法、その可溶化剤および可溶化されたピリドンカルボン酸からなる水性液剤
US6274592B1 (en) 1997-02-04 2001-08-14 Senju Pharmaceutical Co., Ltd. Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
IT1319664B1 (it) * 2000-11-17 2003-10-23 Pharma Biotech Ltd Addotti di antibatterici chinolonici con polimeri polisaccaridicinaturali.
WO2009136408A1 (en) * 2008-04-09 2009-11-12 Institute Of Life Sciences Synergistic pharmaceutical cocrystals

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE944518C (de) * 1950-08-20 1956-06-14 Byk Gulden Lomberg Chem Fab Verfahren zur Herstellung von Loesungen von in 1, 3-Stellung substituierten Xanthinen
US3761592A (en) * 1969-03-18 1973-09-25 R Mizzoni Quinoline derivatives exhibiting growth promoting and anticoccidial effects
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
CA1175836A (en) * 1977-09-20 1984-10-09 Marcel Pesson Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives
AR223983A1 (es) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
US4522819A (en) * 1980-10-02 1985-06-11 Norwich Eaton Pharmaceuticals, Inc. 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid and metal salts thereof useful in burn therapy
ES8304117A1 (es) * 1981-06-11 1983-02-16 Warner Lambert Co "un procedimiento para preparar sales de compuestos de naftiridina y quinoleina".
CA1207773A (en) * 1982-01-13 1986-07-15 Merck & Co., Inc. Quinoline carboxylic acid complexes with guanidinium carbonate
DE3333719A1 (de) * 1983-09-17 1985-04-04 Bayer Ag Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren
HUT40429A (en) * 1985-04-29 1986-12-28 Chinoin Gyogyszer Es Vegyeszet Process for production of salts of derivatives of kynolin carbonic acid

Also Published As

Publication number Publication date
US4792552A (en) 1988-12-20
EP0269278B1 (en) 1992-04-15
EP0269278A3 (en) 1988-08-31
HU198472B (en) 1989-10-30
HUT46687A (en) 1988-11-28
JPH0717609B2 (ja) 1995-03-01
CA1272487A (en) 1990-08-07
DK512187D0 (da) 1987-09-29
EP0269278A2 (en) 1988-06-01
ATE74910T1 (de) 1992-05-15
AU7838787A (en) 1988-05-05
ES2039316T3 (es) 1995-04-01
ES2039316T1 (es) 1993-10-01
DE3778314D1 (de) 1992-05-21
ZA877149B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-04-12
AU597422B2 (en) 1990-05-31
JPS63122681A (ja) 1988-05-26
DK512187A (da) 1988-05-01
DK167530B1 (da) 1993-11-15
IL80459A0 (en) 1987-01-30

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