IL80305A - Process for the preparation of ypsilon-butyrolactams and some novel intermediates - Google Patents

Process for the preparation of ypsilon-butyrolactams and some novel intermediates

Info

Publication number
IL80305A
IL80305A IL80305A IL8030586A IL80305A IL 80305 A IL80305 A IL 80305A IL 80305 A IL80305 A IL 80305A IL 8030586 A IL8030586 A IL 8030586A IL 80305 A IL80305 A IL 80305A
Authority
IL
Israel
Prior art keywords
butyrolactams
ypsilon
preparation
novel intermediates
intermediates
Prior art date
Application number
IL80305A
Other languages
English (en)
Other versions
IL80305A0 (en
Original Assignee
Bayer Ag
Chinese Acad Med Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Chinese Acad Med Science filed Critical Bayer Ag
Publication of IL80305A0 publication Critical patent/IL80305A0/xx
Publication of IL80305A publication Critical patent/IL80305A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL80305A 1985-10-18 1986-10-15 Process for the preparation of ypsilon-butyrolactams and some novel intermediates IL80305A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3537074 1985-10-18
DE19863632589 DE3632589A1 (de) 1985-10-18 1986-09-25 Verfahren zur herstellung von (gamma)-butyrolactamen

Publications (2)

Publication Number Publication Date
IL80305A0 IL80305A0 (en) 1987-01-30
IL80305A true IL80305A (en) 1990-04-29

Family

ID=25837071

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80305A IL80305A (en) 1985-10-18 1986-10-15 Process for the preparation of ypsilon-butyrolactams and some novel intermediates

Country Status (11)

Country Link
US (2) US4731455A (xx)
EP (1) EP0222163B1 (xx)
JP (2) JPH0794431B2 (xx)
KR (1) KR870003980A (xx)
CN (1) CN1019486B (xx)
CA (1) CA1279650C (xx)
DE (2) DE3632589A1 (xx)
DK (1) DK498286A (xx)
ES (1) ES2009757B3 (xx)
HU (1) HU198450B (xx)
IL (1) IL80305A (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3616989A1 (de) * 1986-05-21 1987-11-26 Bayer Ag Enantiomerenreine 4,5-disubstituierte (gamma)-butyrolactame, verfahren zu ihrer herstellung und ihre verwendung
DE3717394A1 (de) * 1987-05-23 1988-12-01 Basf Ag 3-phenyl-2-styryl-pyrrolidine, ihre herstellung und verwendung
DE3717395A1 (de) * 1987-05-23 1988-12-08 Basf Ag 5-phenyl-1,2,3a,4,5,9b-hexahydro-3h-benz(e) indole, ihre herstellung und verwendung als arzneimittel
EG18833A (en) * 1988-12-09 1994-11-30 Kumiai Chemical Industry Co Cyclic amide compounds and herbicides
DE3927370A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate
AU2001296961A1 (en) * 2000-09-29 2002-04-08 Bayer Pharmaceuticals Corporation 17-beta-hydroxysteroid dehydrogenase-ii inhibitors
US6787564B2 (en) * 2002-03-26 2004-09-07 Institute Of Materia Medica, Chinese Academy Of Medical Sciences Optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use
JP6059510B2 (ja) * 2012-11-05 2017-01-11 花王株式会社 セラミド産生促進剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT374457B (de) * 1977-08-18 1984-04-25 Hoechst Ag Verfahren zur herstellung von neuen benzolsulfonamidderivaten
CH646149A5 (de) * 1981-02-05 1984-11-15 Hoffmann La Roche Pyrrolidin-derivat.
US4454327A (en) * 1982-05-24 1984-06-12 Warner-Lambert Company 5-Oxo-2,2-pyrrolidinedipropanoic acid and ester derivatives thereof
DE3346623A1 (de) * 1983-12-14 1985-07-04 Bayer Ag, 5090 Leverkusen N-glycosylierte harnstoffe, carbamate und thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung
DE3508025A1 (de) * 1985-03-07 1986-09-11 Bayer Ag, 5090 Leverkusen Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS61245606A (ja) * 1985-04-23 1986-10-31 Alps Electric Co Ltd マイクロ波発振器

Also Published As

Publication number Publication date
EP0222163B1 (de) 1989-07-19
DE3632589A1 (de) 1987-04-23
JPH0853413A (ja) 1996-02-27
CA1279650C (en) 1991-01-29
KR870003980A (ko) 1987-05-06
CN86106592A (zh) 1987-06-03
DE3664464D1 (en) 1989-08-24
JPS62187451A (ja) 1987-08-15
US4803285A (en) 1989-02-07
HUT46661A (en) 1988-11-28
JPH0794431B2 (ja) 1995-10-11
EP0222163A1 (de) 1987-05-20
DK498286D0 (da) 1986-10-17
JP2520582B2 (ja) 1996-07-31
US4731455A (en) 1988-03-15
DK498286A (da) 1987-04-19
CN1019486B (zh) 1992-12-16
HU198450B (en) 1989-10-30
IL80305A0 (en) 1987-01-30
ES2009757B3 (es) 1989-10-16

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