DK498286A - Fremgangsmaade og mellemprodukter til fremstilling af c(3)--c(4)-trans-konfigurerede gamma-butyrolactamer i form af deres isomere, isomerblandinger, racemater eller optiske antipoder - Google Patents
Fremgangsmaade og mellemprodukter til fremstilling af c(3)--c(4)-trans-konfigurerede gamma-butyrolactamer i form af deres isomere, isomerblandinger, racemater eller optiske antipoder Download PDFInfo
- Publication number
- DK498286A DK498286A DK498286A DK498286A DK498286A DK 498286 A DK498286 A DK 498286A DK 498286 A DK498286 A DK 498286A DK 498286 A DK498286 A DK 498286A DK 498286 A DK498286 A DK 498286A
- Authority
- DK
- Denmark
- Prior art keywords
- butyrolactames
- racemates
- intermediates
- isomers
- trans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3537074 | 1985-10-18 | ||
| DE19863632589 DE3632589A1 (de) | 1985-10-18 | 1986-09-25 | Verfahren zur herstellung von (gamma)-butyrolactamen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK498286D0 DK498286D0 (da) | 1986-10-17 |
| DK498286A true DK498286A (da) | 1987-04-19 |
Family
ID=25837071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK498286A DK498286A (da) | 1985-10-18 | 1986-10-17 | Fremgangsmaade og mellemprodukter til fremstilling af c(3)--c(4)-trans-konfigurerede gamma-butyrolactamer i form af deres isomere, isomerblandinger, racemater eller optiske antipoder |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US4731455A (da) |
| EP (1) | EP0222163B1 (da) |
| JP (2) | JPH0794431B2 (da) |
| KR (1) | KR870003980A (da) |
| CN (1) | CN1019486B (da) |
| CA (1) | CA1279650C (da) |
| DE (2) | DE3632589A1 (da) |
| DK (1) | DK498286A (da) |
| ES (1) | ES2009757B3 (da) |
| HU (1) | HU198450B (da) |
| IL (1) | IL80305A (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3616989A1 (de) * | 1986-05-21 | 1987-11-26 | Bayer Ag | Enantiomerenreine 4,5-disubstituierte (gamma)-butyrolactame, verfahren zu ihrer herstellung und ihre verwendung |
| DE3717394A1 (de) * | 1987-05-23 | 1988-12-01 | Basf Ag | 3-phenyl-2-styryl-pyrrolidine, ihre herstellung und verwendung |
| DE3717395A1 (de) * | 1987-05-23 | 1988-12-08 | Basf Ag | 5-phenyl-1,2,3a,4,5,9b-hexahydro-3h-benz(e) indole, ihre herstellung und verwendung als arzneimittel |
| EG18833A (en) * | 1988-12-09 | 1994-11-30 | Kumiai Chemical Industry Co | Cyclic amide compounds and herbicides |
| DE3927370A1 (de) * | 1989-08-19 | 1991-02-21 | Bayer Ag | Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate |
| AU2001296961A1 (en) * | 2000-09-29 | 2002-04-08 | Bayer Pharmaceuticals Corporation | 17-beta-hydroxysteroid dehydrogenase-ii inhibitors |
| US6787564B2 (en) * | 2002-03-26 | 2004-09-07 | Institute Of Materia Medica, Chinese Academy Of Medical Sciences | Optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use |
| JP6059510B2 (ja) * | 2012-11-05 | 2017-01-11 | 花王株式会社 | セラミド産生促進剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT374457B (de) * | 1977-08-18 | 1984-04-25 | Hoechst Ag | Verfahren zur herstellung von neuen benzolsulfonamidderivaten |
| CH646149A5 (de) * | 1981-02-05 | 1984-11-15 | Hoffmann La Roche | Pyrrolidin-derivat. |
| US4454327A (en) * | 1982-05-24 | 1984-06-12 | Warner-Lambert Company | 5-Oxo-2,2-pyrrolidinedipropanoic acid and ester derivatives thereof |
| DE3346623A1 (de) * | 1983-12-14 | 1985-07-04 | Bayer Ag, 5090 Leverkusen | N-glycosylierte harnstoffe, carbamate und thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung |
| DE3508025A1 (de) * | 1985-03-07 | 1986-09-11 | Bayer Ag, 5090 Leverkusen | Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS61245606A (ja) * | 1985-04-23 | 1986-10-31 | Alps Electric Co Ltd | マイクロ波発振器 |
-
1986
- 1986-09-25 DE DE19863632589 patent/DE3632589A1/de not_active Withdrawn
- 1986-10-01 US US06/914,210 patent/US4731455A/en not_active Expired - Lifetime
- 1986-10-08 ES ES86113938T patent/ES2009757B3/es not_active Expired
- 1986-10-08 DE DE8686113938T patent/DE3664464D1/de not_active Expired
- 1986-10-08 EP EP86113938A patent/EP0222163B1/de not_active Expired
- 1986-10-15 IL IL80305A patent/IL80305A/xx unknown
- 1986-10-16 CA CA000520592A patent/CA1279650C/en not_active Expired - Lifetime
- 1986-10-17 DK DK498286A patent/DK498286A/da not_active Application Discontinuation
- 1986-10-17 HU HU864333A patent/HU198450B/hu not_active IP Right Cessation
- 1986-10-17 JP JP61245607A patent/JPH0794431B2/ja not_active Expired - Lifetime
- 1986-10-17 KR KR1019860008707A patent/KR870003980A/ko not_active Application Discontinuation
- 1986-10-18 CN CN86106592A patent/CN1019486B/zh not_active Expired
-
1987
- 1987-08-27 US US07/089,897 patent/US4803285A/en not_active Expired - Lifetime
-
1995
- 1995-04-04 JP JP7103136A patent/JP2520582B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0222163B1 (de) | 1989-07-19 |
| DE3632589A1 (de) | 1987-04-23 |
| JPH0853413A (ja) | 1996-02-27 |
| CA1279650C (en) | 1991-01-29 |
| KR870003980A (ko) | 1987-05-06 |
| CN86106592A (zh) | 1987-06-03 |
| DE3664464D1 (en) | 1989-08-24 |
| JPS62187451A (ja) | 1987-08-15 |
| US4803285A (en) | 1989-02-07 |
| HUT46661A (en) | 1988-11-28 |
| JPH0794431B2 (ja) | 1995-10-11 |
| EP0222163A1 (de) | 1987-05-20 |
| DK498286D0 (da) | 1986-10-17 |
| JP2520582B2 (ja) | 1996-07-31 |
| US4731455A (en) | 1988-03-15 |
| IL80305A (en) | 1990-04-29 |
| CN1019486B (zh) | 1992-12-16 |
| HU198450B (en) | 1989-10-30 |
| IL80305A0 (en) | 1987-01-30 |
| ES2009757B3 (es) | 1989-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |