IL79661A - Antiviral composition containing hypericin or pseudohypericin - Google Patents
Antiviral composition containing hypericin or pseudohypericinInfo
- Publication number
- IL79661A IL79661A IL79661A IL7966186A IL79661A IL 79661 A IL79661 A IL 79661A IL 79661 A IL79661 A IL 79661A IL 7966186 A IL7966186 A IL 7966186A IL 79661 A IL79661 A IL 79661A
- Authority
- IL
- Israel
- Prior art keywords
- pseudohypericin
- composition containing
- hsv
- hypericin
- antiviral composition
- Prior art date
Links
- YXBUQQDFTYOHQI-UHFFFAOYSA-N Pseudohypericin Chemical compound OC1=CC(O)=C2C(=O)C3=C(O)C=C(C)C4=C3C3=C2C1=C(C(O)=CC(O)=C1C2=O)C1=C3C1=C2C(O)=CC(CO)=C14 YXBUQQDFTYOHQI-UHFFFAOYSA-N 0.000 title abstract 4
- SSKVDVBQSWQEGJ-UHFFFAOYSA-N pseudohypericin Natural products C12=C(O)C=C(O)C(C(C=3C(O)=CC(O)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 SSKVDVBQSWQEGJ-UHFFFAOYSA-N 0.000 title abstract 4
- BTXNYTINYBABQR-UHFFFAOYSA-N hypericin Chemical compound C12=C(O)C=C(O)C(C(C=3C(O)=CC(C)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 BTXNYTINYBABQR-UHFFFAOYSA-N 0.000 title abstract 2
- 229940005608 hypericin Drugs 0.000 title abstract 2
- PHOKTTKFQUYZPI-UHFFFAOYSA-N hypericin Natural products Cc1cc(O)c2c3C(=O)C(=Cc4c(O)c5c(O)cc(O)c6c7C(=O)C(=Cc8c(C)c1c2c(c78)c(c34)c56)O)O PHOKTTKFQUYZPI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- 208000009889 Herpes Simplex Diseases 0.000 abstract 1
- 241000700588 Human alphaherpesvirus 1 Species 0.000 abstract 1
- 241000701074 Human alphaherpesvirus 2 Species 0.000 abstract 1
- 230000006819 RNA synthesis Effects 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000003265 stomatitis Diseases 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 208000005925 vesicular stomatitis Diseases 0.000 abstract 1
- 230000029812 viral genome replication Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL79661A IL79661A (en) | 1986-08-08 | 1986-08-08 | Antiviral composition containing hypericin or pseudohypericin |
ES87111467T ES2061453T3 (es) | 1986-08-08 | 1987-08-07 | Composiciones farmaceuticas antivirales que contienen hipericina o pseudohipericina. |
EP87111467A EP0256452B1 (en) | 1986-08-08 | 1987-08-07 | Antiviral pharmaceutical compositions containing hypericin or pseudohypericin |
AT87111467T ATE96663T1 (de) | 1986-08-08 | 1987-08-07 | Antivirale pharmazeutische zusammensetzungen enthaltende hypericine oder pseudohypericine. |
DE87111467T DE3788016T2 (de) | 1986-08-08 | 1987-08-07 | Antivirale pharmazeutische Zusammensetzungen enthaltende Hypericine oder Pseudohypericine. |
US07/328,767 US5047435A (en) | 1986-08-08 | 1989-03-27 | Antiviral compositions containing aromatic polycyclic diones and method for treating retrovirus infections |
US07/452,436 US5049589A (en) | 1986-08-08 | 1989-12-19 | Antiviral aerosol compositions and pressurized containers containing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL79661A IL79661A (en) | 1986-08-08 | 1986-08-08 | Antiviral composition containing hypericin or pseudohypericin |
Publications (2)
Publication Number | Publication Date |
---|---|
IL79661A0 IL79661A0 (en) | 1987-08-31 |
IL79661A true IL79661A (en) | 1991-01-31 |
Family
ID=11057015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL79661A IL79661A (en) | 1986-08-08 | 1986-08-08 | Antiviral composition containing hypericin or pseudohypericin |
Country Status (6)
Country | Link |
---|---|
US (2) | US5047435A (es) |
EP (1) | EP0256452B1 (es) |
AT (1) | ATE96663T1 (es) |
DE (1) | DE3788016T2 (es) |
ES (1) | ES2061453T3 (es) |
IL (1) | IL79661A (es) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6056961A (en) * | 1996-12-15 | 2000-05-02 | Lavie; David | Plant extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis |
US6428819B1 (en) | 1996-12-15 | 2002-08-06 | David Lavie | Plant extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9309574B1 (en) | 1984-08-22 | 2016-04-12 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Molecular cloning of HIV-1 from immortalized cell lines |
DE332679T1 (de) * | 1987-08-10 | 1990-04-12 | New York University, New York, N.Y. | Antivirale zusammensetzungen mit aromatischen polycyclischen dionen sowie methode zur behandlung retroviraler infektionen. |
AU3423989A (en) * | 1988-03-23 | 1989-10-16 | New York University | Antiviral composition containing aromatic polycyclic diones and nucleoside analogs and method for treating retrovirus infections |
WO1989009055A1 (en) * | 1988-03-23 | 1989-10-05 | New York University | Antiviral composition containing aromatic polycyclic diones and nucleoside analogs and method for treating retrovirus infections |
IL93682A (en) * | 1989-03-16 | 1996-06-18 | Yeda Res & Dev | Polycyclic compounds with antigypical activity are used in the manufacture of medicines and pharmaceutical preparations containing them |
US5418130A (en) * | 1990-04-16 | 1995-05-23 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
US6187572B1 (en) | 1990-04-16 | 2001-02-13 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants |
US5316768A (en) * | 1990-12-28 | 1994-05-31 | Murdock International Corporation | Pharmaceutical compositions having antiviral activity against human cytomegalovirus |
AU3474593A (en) * | 1992-01-16 | 1993-08-03 | New York University | Hypericin treatment of vaccine agents for improved immunogenicity |
WO1994014956A1 (en) * | 1992-12-23 | 1994-07-07 | Iowa State University Research Foundation, Inc. | Molecular flashlight |
DE9316320U1 (de) * | 1993-10-20 | 1994-01-20 | Beni Med Natuerliche Heilmitte | Kosmetische Zubereitung in Form von Lippenstiften mit antiviraler Wirkung |
DE19547317A1 (de) * | 1995-12-18 | 1998-12-24 | Dreluso Pharm Dr Elten & Sohn | Antivirales Medikament |
GR1002799B (el) * | 1996-11-19 | 1997-11-04 | Αντιικη δραση του φυτου hypericum perforatum l. κατα του ανθρωπινου κυτταρομεγαλοιου. | |
DE19700788A1 (de) * | 1997-01-11 | 1998-07-16 | Michael O Ruepp | Johanniskraut-Trockenextrakte |
IL121440A0 (en) | 1997-07-31 | 1998-01-04 | Yeda Res & Dev | The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives |
US6096317A (en) * | 1998-01-13 | 2000-08-01 | Rexall Sundown | St. John's Wort and methyl donor composition and uses thereof |
US6238671B1 (en) | 1998-04-22 | 2001-05-29 | Bionorica Arzneimittel Gmbh | Process for the gentle recovery of extract fractions from hypericum, pharmaceutical preparations containing the same and their use |
US6159986A (en) * | 1999-11-02 | 2000-12-12 | Altman; David A. | Compounds and therapy for resisting memory loss in humans |
DE10131641A1 (de) | 2000-12-22 | 2002-06-27 | Schwabe Willmar Gmbh & Co | Verbesserter und stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und Verwendung als topisches Arzneimittel |
US7037534B2 (en) * | 2001-10-24 | 2006-05-02 | Aphios Corporation | Inactivation of viral infections agents by chemiluminescence activated light-sensitive compounds |
EP1569630A4 (en) * | 2002-11-25 | 2009-03-04 | Univ New York | METHODS FOR PREVENTING OTOTOXIC PH DAMAGE OF US TISSUES DURING PHOTODYNAMIC THERAPY |
CA2659800A1 (en) * | 2006-08-03 | 2008-02-07 | Hy Biopharma Inc. | Polycyclic dianthraquinones as inhibitors of inflammatory cytokines |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2707704A (en) * | 1951-09-29 | 1955-05-03 | Schenley Ind Inc | Process for the preparation of hypericin |
US4209532A (en) * | 1977-03-28 | 1980-06-24 | Union Carbide Corporation | Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof |
US4338122A (en) * | 1979-09-26 | 1982-07-06 | Union Carbide Corporation | Biocidal 2-aryl-1,3-cyclopentanedione compounds and alkali metal and ammonium salts thereof |
DE3260474D1 (en) * | 1981-02-02 | 1984-09-06 | Schering Corp | Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them |
US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
JPS59190921A (ja) * | 1983-04-11 | 1984-10-29 | Junko Nozaki | 抗ウイルス活性物質 |
-
1986
- 1986-08-08 IL IL79661A patent/IL79661A/xx not_active IP Right Cessation
-
1987
- 1987-08-07 ES ES87111467T patent/ES2061453T3/es not_active Expired - Lifetime
- 1987-08-07 DE DE87111467T patent/DE3788016T2/de not_active Expired - Fee Related
- 1987-08-07 AT AT87111467T patent/ATE96663T1/de not_active IP Right Cessation
- 1987-08-07 EP EP87111467A patent/EP0256452B1/en not_active Expired - Lifetime
-
1989
- 1989-03-27 US US07/328,767 patent/US5047435A/en not_active Expired - Fee Related
- 1989-12-19 US US07/452,436 patent/US5049589A/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6056961A (en) * | 1996-12-15 | 2000-05-02 | Lavie; David | Plant extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis |
US6428819B1 (en) | 1996-12-15 | 2002-08-06 | David Lavie | Plant extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis |
Also Published As
Publication number | Publication date |
---|---|
DE3788016D1 (de) | 1993-12-09 |
US5049589A (en) | 1991-09-17 |
EP0256452A2 (en) | 1988-02-24 |
EP0256452A3 (en) | 1990-01-17 |
DE3788016T2 (de) | 1994-03-03 |
EP0256452B1 (en) | 1993-11-03 |
ATE96663T1 (de) | 1993-11-15 |
IL79661A0 (en) | 1987-08-31 |
US5047435A (en) | 1991-09-10 |
ES2061453T3 (es) | 1994-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |