IL76897A - Crystalline 2-penem-3-carboxylic acid derivative,its manufacture and pharmaceutical compositions containing it - Google Patents
Crystalline 2-penem-3-carboxylic acid derivative,its manufacture and pharmaceutical compositions containing itInfo
- Publication number
- IL76897A IL76897A IL76897A IL7689785A IL76897A IL 76897 A IL76897 A IL 76897A IL 76897 A IL76897 A IL 76897A IL 7689785 A IL7689785 A IL 7689785A IL 76897 A IL76897 A IL 76897A
- Authority
- IL
- Israel
- Prior art keywords
- penem
- crystalline
- manufacture
- carboxylic acid
- pharmaceutical compositions
- Prior art date
Links
- DUNKKIRUWZSMPT-RXMQYKEDSA-N (5r)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical class OC(=O)C1=CS[C@@H]2CC(=O)N12 DUNKKIRUWZSMPT-RXMQYKEDSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH526684 | 1984-11-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL76897A0 IL76897A0 (en) | 1986-02-28 |
IL76897A true IL76897A (en) | 1989-10-31 |
Family
ID=4290719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL76897A IL76897A (en) | 1984-11-02 | 1985-10-31 | Crystalline 2-penem-3-carboxylic acid derivative,its manufacture and pharmaceutical compositions containing it |
Country Status (17)
Country | Link |
---|---|
US (1) | US4761408A (hu) |
EP (1) | EP0181571A1 (hu) |
JP (1) | JPS61165390A (hu) |
KR (1) | KR890001009B1 (hu) |
AU (1) | AU580636B2 (hu) |
DD (1) | DD242408A5 (hu) |
DK (1) | DK505485A (hu) |
ES (1) | ES8701765A1 (hu) |
FI (1) | FI854268A (hu) |
GR (1) | GR852625B (hu) |
HU (1) | HUT39184A (hu) |
IL (1) | IL76897A (hu) |
NO (1) | NO854364L (hu) |
NZ (1) | NZ214046A (hu) |
PH (1) | PH23259A (hu) |
PT (1) | PT81411B (hu) |
ZA (1) | ZA858402B (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT84767B (en) * | 1986-04-29 | 1989-06-09 | Ciba Geigy Ag | Process for preparing a crystalline (5r.6s)-2-aminomethyl-6-](1r)-1-hydroxyethyl"-2-penem-3-carboxylic acid hydrate |
IE60588B1 (en) * | 1986-07-30 | 1994-07-27 | Sumitomo Pharma | Carbapenem compound in crystalline form, and its production and use |
GB8818789D0 (en) * | 1988-08-08 | 1988-09-07 | Erba Carlo Spa | Crystalline(5r 6s)-2-carbamoyloxymethyl-6-((1r)-hydroxyethyl)-2-penem-carboxylic acid & pharmaceutical formulation |
DK1138333T3 (da) * | 1999-10-12 | 2004-05-24 | Daiichi Suntory Pharma Co Ltd | Medicinske præparater til oral anvendelse |
US20040202714A1 (en) * | 1999-10-12 | 2004-10-14 | Daiichi Suntory Pharma Co., Ltd. | Oral pharmaceutical composition |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
US4272437A (en) * | 1978-12-18 | 1981-06-09 | Bristol-Myers Company | Antibacterial agents, and 4-thio azetidinone intermediates |
IL59081A0 (en) * | 1979-01-10 | 1980-05-30 | Schering Corp | 2-penem compounds and a method for preparing them |
IT1193922B (it) * | 1979-02-24 | 1988-08-31 | Erba Farmitalia | Agenti antibatterici ed inibitori di beta -lattamasi e loro preparazione |
US4386030A (en) * | 1979-12-31 | 1983-05-31 | Merck & Co., Inc. | Process for preparing 6-(1'-hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid |
US4347183A (en) * | 1981-02-02 | 1982-08-31 | Schering Corporation | Process for the synthesis of penems and carbapenems |
JPS588084A (ja) * | 1981-07-08 | 1983-01-18 | Takeda Chem Ind Ltd | (6r)−置換−(5r)−ペネム−3−カルボン酸誘導体およびその製造法 |
DE3277696D1 (en) * | 1981-07-15 | 1987-12-23 | Sumitomo Pharma | Carboxylic beta-lactam compounds and the preparation thereof |
US4540580A (en) * | 1982-11-16 | 1985-09-10 | Schering Corporation | 2-[(1'R)-1'-Aminoalkyl]penems |
EP0125208A1 (de) * | 1983-05-06 | 1984-11-14 | Ciba-Geigy Ag | Aminoniederalkyl-penem-Verbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren |
EP0132101A1 (en) * | 1983-07-14 | 1985-01-23 | Pfizer Inc. | 2-Heterocycloalkylthiopenem derivatives |
US4656165A (en) * | 1983-09-02 | 1987-04-07 | Ciba-Geigy Corporation | Aminomethyl penem compounds |
US4634556A (en) * | 1985-05-10 | 1987-01-06 | Schering Corporation | Crystalline sodium (5R, 6S, 8R)-6-(1-hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylate and process for making same |
-
1985
- 1985-10-28 US US06/792,076 patent/US4761408A/en not_active Expired - Fee Related
- 1985-10-30 PH PH32993A patent/PH23259A/en unknown
- 1985-10-30 EP EP85113841A patent/EP0181571A1/de not_active Withdrawn
- 1985-10-30 FI FI854268A patent/FI854268A/fi not_active IP Right Cessation
- 1985-10-31 PT PT81411A patent/PT81411B/pt unknown
- 1985-10-31 GR GR852625A patent/GR852625B/el unknown
- 1985-10-31 DD DD85282294A patent/DD242408A5/de unknown
- 1985-10-31 IL IL76897A patent/IL76897A/xx unknown
- 1985-10-31 ES ES548435A patent/ES8701765A1/es not_active Expired
- 1985-11-01 NZ NZ214046A patent/NZ214046A/xx unknown
- 1985-11-01 AU AU49306/85A patent/AU580636B2/en not_active Ceased
- 1985-11-01 NO NO854364A patent/NO854364L/no unknown
- 1985-11-01 JP JP60244201A patent/JPS61165390A/ja active Pending
- 1985-11-01 DK DK505485A patent/DK505485A/da not_active Application Discontinuation
- 1985-11-01 ZA ZA858402A patent/ZA858402B/xx unknown
- 1985-11-01 HU HU854202A patent/HUT39184A/hu unknown
- 1985-11-02 KR KR1019850008172A patent/KR890001009B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR890001009B1 (ko) | 1989-04-18 |
KR860004064A (ko) | 1986-06-16 |
ZA858402B (en) | 1986-06-25 |
PT81411B (en) | 1987-08-04 |
HUT39184A (en) | 1986-08-28 |
FI854268A (fi) | 1986-05-03 |
IL76897A0 (en) | 1986-02-28 |
PT81411A (en) | 1985-11-01 |
DK505485D0 (da) | 1985-11-01 |
DK505485A (da) | 1986-05-03 |
ES8701765A1 (es) | 1986-12-01 |
ES548435A0 (es) | 1986-12-01 |
AU580636B2 (en) | 1989-01-19 |
GR852625B (hu) | 1986-03-03 |
AU4930685A (en) | 1986-05-08 |
FI854268A0 (fi) | 1985-10-30 |
JPS61165390A (ja) | 1986-07-26 |
NZ214046A (en) | 1988-09-29 |
PH23259A (en) | 1989-06-16 |
NO854364L (no) | 1986-05-05 |
EP0181571A1 (de) | 1986-05-21 |
DD242408A5 (de) | 1987-01-28 |
US4761408A (en) | 1988-08-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL76453A (en) | Isoxazolecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL74882A0 (en) | Naphthyridine-,quinoline-and benzoxazine-carboxylic acids and derivatives thereof,their manufacture and pharmaceutical compositions containing them | |
IL75586A0 (en) | Pharmaceutical compositions containing indole-2-alkanoic acids and derivatives thereof,and certain such novel compounds | |
IL77004A0 (en) | 5-amino-4-hydroxyvaleryl derivatives,their manufacture and pharmaceutical compositions containing them | |
IL68323A0 (en) | Phenoxyalkylcarboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them | |
IL74826A0 (en) | 3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL83049A (en) | 4-quinolinone-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them | |
IL75720A0 (en) | Morpholinol compounds,their preparation and pharmaceutical compositions containing them | |
GB2201676B (en) | Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it | |
IL75603A0 (en) | 1,3-dioxanylheptenoic acid derivatives,their preparation and pharmaceutical compositions containing them | |
DE3573428D1 (en) | Novel delta4- and delta5- androstene derivatives, processes for their preparation and pharmaceutical compositions containing these derivatives | |
IL75913A0 (en) | Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them | |
HK86292A (en) | Dihydroorotic acid derivatives,processes for their prepararing and pharmaceutical composition containing them | |
IL76897A (en) | Crystalline 2-penem-3-carboxylic acid derivative,its manufacture and pharmaceutical compositions containing it | |
IL76327A (en) | Phenylacetonitrile derivatives,process for the preparation thereof and pharmaceutical compositions containing the same | |
AU589933B2 (en) | 8 alpha-acylaminoergoline, its production and pharmaceutical compositions containing it | |
DE3569526D1 (en) | Glutarimide derivatives, their preparation and pharmaceutical compositions containing them | |
IL75775A0 (en) | Aminoeburnanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL75776A0 (en) | Nitroapovincaminic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL72079A (en) | 4-benzoyl-5-hydroxy-1-benzocyclobutenecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL74616A0 (en) | Substituted isochromanes and benzoxepines,and acid addition salts thereof,their preparation and pharmaceutical compositions containing them | |
IL76511A (en) | Dihydropyridine dicarboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
DE3564806D1 (en) | Benzoylpropionic acid derivatives, their use and pharmaceutical compositions | |
IL71392A0 (en) | 7beta-acylamido-3-cephem-4-carboxylic acid compounds,their manufacture and pharmaceutical compositions containing them | |
IL65108A0 (en) | 7-acylamido-3-cephem-4-carboxylic acid compounds,their manufacture and pharmaceutical compositions containing them |