IL74827A - Peptides active as gnrh antagonists and pharmaceutical compositions containing them - Google Patents

Peptides active as gnrh antagonists and pharmaceutical compositions containing them

Info

Publication number
IL74827A
IL74827A IL74827A IL7482785A IL74827A IL 74827 A IL74827 A IL 74827A IL 74827 A IL74827 A IL 74827A IL 7482785 A IL7482785 A IL 7482785A IL 74827 A IL74827 A IL 74827A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
gnrh antagonists
peptides active
peptides
Prior art date
Application number
IL74827A
Other languages
English (en)
Other versions
IL74827A0 (en
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/612,072 external-priority patent/US4569927A/en
Priority claimed from US06/653,867 external-priority patent/US4652550A/en
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of IL74827A0 publication Critical patent/IL74827A0/xx
Publication of IL74827A publication Critical patent/IL74827A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL74827A 1984-05-21 1985-04-05 Peptides active as gnrh antagonists and pharmaceutical compositions containing them IL74827A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/612,072 US4569927A (en) 1984-02-23 1984-05-21 GnRH Antagonists IV
US06/653,867 US4652550A (en) 1984-05-21 1984-09-21 GnRH antagonists VII
US69669985A 1985-01-31 1985-01-31

Publications (2)

Publication Number Publication Date
IL74827A0 IL74827A0 (en) 1985-07-31
IL74827A true IL74827A (en) 1989-06-30

Family

ID=27417072

Family Applications (1)

Application Number Title Priority Date Filing Date
IL74827A IL74827A (en) 1984-05-21 1985-04-05 Peptides active as gnrh antagonists and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0162575B1 (fr)
JP (1) JPH0725795B2 (fr)
AU (1) AU580598B2 (fr)
CA (1) CA1302650C (fr)
DE (1) DE3583964D1 (fr)
DK (1) DK166214C (fr)
ES (1) ES8802234A1 (fr)
GR (1) GR851205B (fr)
HU (1) HU198089B (fr)
IL (1) IL74827A (fr)
MX (1) MX160995A (fr)
NZ (1) NZ212124A (fr)
PH (1) PH22655A (fr)
PT (1) PT80443B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795740A (en) * 1986-05-20 1989-01-03 Cohen Eric A Antiviral peptides and means for treating herpes infections
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
WO1989007451A1 (fr) * 1988-02-10 1989-08-24 Abbott Laboratories Analogues de l'hormone de liberation de l'hormone de luteinisation a taille reduite
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists
JP2672677B2 (ja) * 1989-02-09 1997-11-05 タツプ・フアーマシユーテイカルズ・インコーポレイテツド Ｌｈｒｈ同族体
US5480969A (en) * 1992-09-15 1996-01-02 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US5656727A (en) * 1992-09-15 1997-08-12 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US6602856B1 (en) 1995-01-17 2003-08-05 J. Mark Quillan Antagonists of alpha-melanocyte stimulating hormone and methods based thereon
EP1343808B1 (fr) 2000-12-22 2006-09-13 Ipsen Manufacturing Ireland Limited Procede de synthese d'un peptide lhrh
US20060241051A1 (en) 2002-12-26 2006-10-26 Chieko Kitada Metastin derivatives and use thereof
WO2004080479A1 (fr) 2003-03-12 2004-09-23 Takeda Pharmaceutical Company Limited Agents ameliorant la fonction gonadique
BRPI0512397A (pt) 2004-06-25 2008-03-04 Takeda Pharmaceutical composto,produto farmacêutico, métodos para suprimir a metástase de cáncer ou o crescimento do cáncer, para prevenir ou tratar uma doença ou condição, para controlar a função placentária, para melhorar a função gonadal, para induzir ou estimular a ovulação, para promover a secreção do hormÈnio gonadotrópico ou promover a secreção do hormÈnio sexual, para suprimir a secreção do hormÈnio gonadotrópico ou suprimir a secreção do hormÈnio sexual, para infra regular hormÈnio gonadrotópico ou hormÈnio sexual, e a proteìna ot7t175 humana, e para realçar a estabilidade no sangue, uso do composto, e, agente para suprimir a secreção do hormÈnio gonadotrópico ou um agente para suprimir a secreção do hormÈnio sexual
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933782A (en) * 1974-11-14 1976-01-20 American Home Products Corporation (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates
US4215038A (en) 1978-10-16 1980-07-29 The Salk Institute For Biological Studies Peptides which inhibit gonadal function
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor
US4409208A (en) * 1980-04-15 1983-10-11 The Salk Institute For Biological Studies GnRH antagonists
US4292313A (en) * 1980-04-15 1981-09-29 The Salk Institute For Biological Studies LRF Antagonists
NZ196558A (en) * 1980-04-15 1984-10-19 Salk Inst For Biological Studi Lrf antagonists and pharmaceutical compositions
DE3165535D1 (en) * 1980-06-02 1984-09-20 Andrew Victor Schally Lh-rh antagonists
US4341767A (en) * 1980-10-06 1982-07-27 Syntex Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
JPS57162562A (en) * 1981-03-30 1982-10-06 Nec Corp Delay wave detecting circuit
ZA829041B (en) * 1981-12-10 1983-09-28 David Howard Coy Lh-rh antagonists
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
ZA84912B (en) * 1983-03-10 1984-09-26 Salk Inst For Biological Studi Gnrh antagonists
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4504414A (en) * 1983-03-28 1985-03-12 Board Of Regents, The University Of Texas System Synthetic pyridyl-alanyl decapeptides having antiovulatory activity

Also Published As

Publication number Publication date
EP0162575A3 (en) 1987-10-07
PH22655A (en) 1988-10-28
HU198089B (en) 1989-07-28
GR851205B (fr) 1985-11-25
JPS60260594A (ja) 1985-12-23
MX160995A (es) 1990-06-29
DK166214C (da) 1993-08-16
DK224985A (da) 1985-11-22
DK224985D0 (da) 1985-05-21
NZ212124A (en) 1989-04-26
HUT37634A (en) 1986-01-23
AU580598B2 (en) 1989-01-19
PT80443B (en) 1986-12-15
EP0162575B1 (fr) 1991-09-04
JPH0725795B2 (ja) 1995-03-22
CA1302650C (fr) 1992-06-02
IL74827A0 (en) 1985-07-31
ES8802234A1 (es) 1988-04-16
EP0162575A2 (fr) 1985-11-27
DK166214B (da) 1993-03-22
DE3583964D1 (de) 1991-10-10
AU4244785A (en) 1985-11-28
PT80443A (en) 1985-06-01
ES543284A0 (es) 1988-04-16

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