IL74539A - Nucelic acid-protein conjugates,their preparation and their use in immunoassays - Google Patents

Nucelic acid-protein conjugates,their preparation and their use in immunoassays

Info

Publication number
IL74539A
IL74539A IL74539A IL7453985A IL74539A IL 74539 A IL74539 A IL 74539A IL 74539 A IL74539 A IL 74539A IL 7453985 A IL7453985 A IL 7453985A IL 74539 A IL74539 A IL 74539A
Authority
IL
Israel
Prior art keywords
immunoassays
preparation
protein conjugates
nucelic acid
nucelic
Prior art date
Application number
IL74539A
Other languages
English (en)
Other versions
IL74539A0 (en
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Publication of IL74539A0 publication Critical patent/IL74539A0/xx
Publication of IL74539A publication Critical patent/IL74539A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/828—Protein A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL74539A 1984-03-12 1985-03-07 Nucelic acid-protein conjugates,their preparation and their use in immunoassays IL74539A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/588,858 US4748111A (en) 1984-03-12 1984-03-12 Nucleic acid-protein conjugate used in immunoassay

Publications (2)

Publication Number Publication Date
IL74539A0 IL74539A0 (en) 1985-06-30
IL74539A true IL74539A (en) 1989-01-31

Family

ID=24355587

Family Applications (1)

Application Number Title Priority Date Filing Date
IL74539A IL74539A (en) 1984-03-12 1985-03-07 Nucelic acid-protein conjugates,their preparation and their use in immunoassays

Country Status (12)

Country Link
US (1) US4748111A (da)
EP (1) EP0154884A3 (da)
JP (1) JPS60226900A (da)
AU (1) AU578933B2 (da)
CA (1) CA1222706A (da)
DK (1) DK110885A (da)
ES (1) ES8606653A1 (da)
FI (1) FI850925L (da)
IL (1) IL74539A (da)
NO (1) NO850769L (da)
NZ (1) NZ211366A (da)
ZA (1) ZA851797B (da)

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DE3732145A1 (de) * 1987-09-24 1989-04-06 Merck Patent Gmbh Verfahren und reagenz zur durchfuehrung von hybridisierungsreaktionen
US5428132A (en) * 1987-10-11 1995-06-27 United States Of America Conjugate and method for integration of foreign DNA into cells
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5656731A (en) * 1987-10-15 1997-08-12 Chiron Corporation Nucleic acid-amplified immunoassay probes
US5525465A (en) * 1987-10-28 1996-06-11 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates and methods of production and applications of the same
DE3856406T2 (de) * 1987-10-28 2000-10-19 Howard Florey Institute Of Experimental Physiology And Medicine, Parkville Oligonucleotid-polyamid konjugate
US4921788A (en) * 1988-04-12 1990-05-01 The Research Foundation Of State University Of New York Competitive nucleic acid immunoassay for the detection of analytes
US5109124A (en) * 1988-06-01 1992-04-28 Biogen, Inc. Nucleic acid probe linked to a label having a terminal cysteine
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US5783687A (en) * 1990-03-14 1998-07-21 The Regents Of The University Of California Dyes designed for high sensitivity detection of double-stranded DNA
US5763162A (en) 1990-03-14 1998-06-09 The Regents Of University Of California Multichromophore fluorescent DNA intercalation complexes
ATE174121T1 (de) * 1990-05-04 1998-12-15 Chiron Corp Protein-nukleinsäuresonden und selbige verwendende immunoassays
US5677440A (en) * 1990-07-16 1997-10-14 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates
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WO1992014758A1 (en) * 1991-02-13 1992-09-03 The Austin Research Institute Conjugate molecules
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JPH05149949A (ja) * 1991-11-26 1993-06-15 Nisshin Flour Milling Co Ltd 新規な微量物質測定法
US5747244A (en) * 1991-12-23 1998-05-05 Chiron Corporation Nucleic acid probes immobilized on polystyrene surfaces
ATE245446T1 (de) * 1992-02-11 2003-08-15 Jackson H M Found Military Med Dualer träger für immunogene konstrukte
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5354658A (en) * 1993-01-28 1994-10-11 Dennis Wright Non-radioactive method for detecting a labelled segment and a solution or composition therefor
CA2162568C (en) * 1993-05-10 2001-10-30 Yuichi Oku Method and reagent for simultaneously assaying one or more ligands in a group of preselected ligands
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US5876924A (en) * 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
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SE504798C2 (sv) * 1995-06-16 1997-04-28 Ulf Landegren Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
AU714486B2 (en) 1995-11-21 2000-01-06 Yale University Unimolecular segment amplification and detection
US6255048B1 (en) * 1996-06-10 2001-07-03 Laboratory Of Molecular Biophotonics Highly sensitive fluoroassay
DE69739163D1 (de) * 1996-10-17 2009-01-22 Mitsubishi Chem Corp Molekül, welches Genotyp und Phänotyp zusammenführt und dessen Anwendungen
US6225074B1 (en) 1997-08-18 2001-05-01 Dennis Wright Direct chloramphenicol acetyl transferase assay
US6316229B1 (en) 1998-07-20 2001-11-13 Yale University Single molecule analysis target-mediated ligation of bipartite primers
AU770993B2 (en) 1998-09-15 2004-03-11 Yale University Molecular cloning using rolling circle amplification
JP2002525078A (ja) 1998-09-15 2002-08-13 イェール ユニバーシティ 人工的長末端反復配列
US6203989B1 (en) * 1998-09-30 2001-03-20 Affymetrix, Inc. Methods and compositions for amplifying detectable signals in specific binding assays
US6232068B1 (en) * 1999-01-22 2001-05-15 Rosetta Inpharmatics, Inc. Monitoring of gene expression by detecting hybridization to nucleic acid arrays using anti-heteronucleic acid antibodies
FR2791141B1 (fr) * 1999-03-15 2001-06-01 Cis Bio Int Procede de reduction de l'extinction de fluorescence due au milieu de mesure
AU779491B2 (en) * 1999-06-01 2005-01-27 Bristol-Myers Squibb Company Methods for producing 5'-nucleic acid-protein conjugates
US20060166227A1 (en) * 2000-06-20 2006-07-27 Stephen Kingsmore Protein expression profiling
US6323009B1 (en) * 2000-06-28 2001-11-27 Molecular Staging, Inc. Multiply-primed amplification of nucleic acid sequences
US6686157B2 (en) 2000-06-30 2004-02-03 Molecular Staging Inc. Signal amplification with lollipop probes
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US6573051B2 (en) * 2001-03-09 2003-06-03 Molecular Staging, Inc. Open circle probes with intramolecular stem structures
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US20040003559A1 (en) * 2002-04-24 2004-01-08 Minke Ronald C. Doors and methods of producing same
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US8043834B2 (en) 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
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MX2010008919A (es) * 2008-02-14 2010-09-07 3M Innovative Properties Co Metodos y composiciones para detectar mocroorganismos.
KR101249273B1 (ko) * 2008-05-05 2013-04-01 다우 글로벌 테크놀로지스 엘엘씨 가요성 시트의 가장자리를 감싸는 개선된 방법
US9778188B2 (en) 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
US9482615B2 (en) * 2010-03-15 2016-11-01 Industrial Technology Research Institute Single-molecule detection system and methods
US8865078B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
US8865077B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
CN105378477B9 (zh) 2013-03-11 2021-08-06 梅索磅秤技术有限公司 用于进行多路测定法的改进方法
CN115060912B (zh) * 2022-06-23 2024-02-02 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法

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Also Published As

Publication number Publication date
JPS60226900A (ja) 1985-11-12
EP0154884A2 (en) 1985-09-18
FI850925A0 (fi) 1985-03-08
FI850925L (fi) 1985-09-13
AU3943485A (en) 1985-09-19
NZ211366A (en) 1988-05-30
ES541077A0 (es) 1986-04-16
ZA851797B (en) 1985-11-27
NO850769L (no) 1985-09-13
DK110885D0 (da) 1985-03-11
IL74539A0 (en) 1985-06-30
CA1222706A (en) 1987-06-09
ES8606653A1 (es) 1986-04-16
EP0154884A3 (en) 1988-11-30
AU578933B2 (en) 1988-11-10
DK110885A (da) 1985-09-13
US4748111A (en) 1988-05-31

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Legal Events

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HC Change of name of proprietor(s)