IL73920A - Glycerine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Glycerine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL73920A
IL73920A IL73920A IL7392084A IL73920A IL 73920 A IL73920 A IL 73920A IL 73920 A IL73920 A IL 73920A IL 7392084 A IL7392084 A IL 7392084A IL 73920 A IL73920 A IL 73920A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
glycerine derivatives
glycerine
Prior art date
Application number
IL73920A
Other languages
English (en)
Other versions
IL73920A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL73920A0 publication Critical patent/IL73920A0/xx
Publication of IL73920A publication Critical patent/IL73920A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL73920A 1983-12-30 1984-12-24 Glycerine derivatives,their preparation and pharmaceutical compositions containing them IL73920A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH698583 1983-12-30
CH449884 1984-09-20

Publications (2)

Publication Number Publication Date
IL73920A0 IL73920A0 (en) 1985-03-31
IL73920A true IL73920A (en) 1988-06-30

Family

ID=25695617

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73920A IL73920A (en) 1983-12-30 1984-12-24 Glycerine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US4731373A (da)
EP (1) EP0147768B1 (da)
AU (1) AU571625B2 (da)
CA (1) CA1266476A (da)
DE (1) DE3476661D1 (da)
DK (2) DK160818C (da)
ES (2) ES539136A0 (da)
FI (1) FI82686C (da)
HU (1) HU195775B (da)
IL (1) IL73920A (da)
MC (1) MC1639A1 (da)
NO (1) NO165192C (da)
NZ (1) NZ210633A (da)
PH (1) PH21482A (da)
PT (1) PT79783B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737518A (en) * 1984-04-03 1988-04-12 Takeda Chemical Industries, Ltd. Lipid derivatives, their production and use
AU4727085A (en) * 1984-08-23 1986-03-24 Sandoz Ag Cyclimmonium salts
US4863941A (en) * 1985-06-18 1989-09-05 Hoffmann-La Roche Inc. Glycerol derivatives
GB8528959D0 (en) * 1985-11-25 1986-01-02 Leo Pharm Prod Ltd Chemical compounds
US5089657A (en) * 1987-03-11 1992-02-18 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
EP0301751B1 (en) * 1987-07-31 1993-03-10 Takeda Chemical Industries, Ltd. Pyridinium derivatives, their production and use
US4920134A (en) * 1987-08-07 1990-04-24 Takeda Chemical Industries, Ltd. 2-O-pyrimidinyl glycerol derivatives
ES2005031A6 (es) * 1987-10-13 1989-02-16 Uriach & Cia Sa J Procedimiento para la obtencion de 1,3-dioxolanos 2,4-disustituidos.
WO1989007100A1 (en) * 1988-02-05 1989-08-10 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
US5185334A (en) * 1989-07-31 1993-02-09 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
WO1989007099A1 (en) * 1988-02-05 1989-08-10 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
EP0336142A3 (en) * 1988-04-04 1991-04-24 American Cyanamid Company Novel antagonists of platelet activating factor
US5273985A (en) * 1988-07-04 1993-12-28 Eisai Co., Ltd. Glycerin derivative and its pharmacological use
FI97883C (fi) * 1988-07-04 1997-03-10 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen glyserolijohdannaisen valmistamiseksi
EP0356765A3 (en) * 1988-08-19 1991-08-07 Takeda Chemical Industries, Ltd. Carboxylic acid derivatives, their production and use
US4981860A (en) * 1989-01-30 1991-01-01 Takeda Chemical Industries, Ltd. Pyridinium nitrate, composition containing same and their use for inhibiting platelet activating factor
ES2013834A6 (es) * 1989-01-30 1990-06-01 Uriach & Cia Sa J Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano.
ES2010145A6 (es) * 1989-03-02 1989-10-16 Uriach & Cia Sa J Procedimiento para la obtencion de derivados de la 2-picolilamina.
US5391785A (en) * 1990-01-16 1995-02-21 La Jolla Pharmaceutial Company Intermediates for providing functional groups on the 5' end of oligonucleotides
JP2899111B2 (ja) * 1991-07-15 1999-06-02 ラ ホヤ ファーマシューティカル カンパニー オリゴヌクレオチドの５’末端へ官能基を提供するための修飾された亜リン酸中間体
ES2062943B1 (es) * 1993-03-23 1995-11-16 Uriach & Cia Sa J Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas.
KR100361933B1 (ko) * 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
US6458953B1 (en) * 1998-12-09 2002-10-01 La Jolla Pharmaceutical Company Valency platform molecules comprising carbamate linkages
US6951939B2 (en) * 2000-06-08 2005-10-04 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
RU2414453C2 (ru) * 2008-07-17 2011-03-20 Сергей Иванович МАЛЕКИН 1-алкил-2-алкилкарбамоил-глицерины, обладающие антигипертензивной активностью, и способ их получения
KR102049711B1 (ko) 2012-03-30 2019-11-28 미쯔비시 케미컬 주식회사 에폭시 화합물의 제조 방법 및 에폭시화 반응용 촉매 조성물
RU2621347C1 (ru) * 2016-05-27 2017-06-02 Государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет "Министерства здравоохранения Российской Федерации (ГБОУ ВПО СибГМУ Минздрава России) Способ получения 1-алкил-2-алкилкарбамоилглицеринов

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE932611C (de) * 1949-12-22 1955-09-05 Ciba Geigy Verfahren zur Herstellung von Polyalkylenglykolaethern isocyclischer Verbindungen
DE1199254B (de) * 1963-09-20 1965-08-26 Krewel Leuffen Gmbh Verfahren zur Herstellung von O, N-Dicarbaethoxyderivaten von substituierten 1, 3-Aminoalkoholen
NL133296C (da) * 1966-12-30
BE741022A (da) * 1968-11-02 1970-04-01
US3686238A (en) * 1970-01-19 1972-08-22 Syntex Corp Glycerol esterified with 2-naphthyl-acetic acids and fatty acids
US3671557A (en) * 1970-09-17 1972-06-20 Smith Kline French Lab 1,2-diacylglycerol 3-(2,2,2-trichloroethyl) carbonates
DE2422170C2 (de) * 1974-05-08 1982-09-23 Bayer Ag, 5090 Leverkusen Polymerisierbare N,N-disubstituierte Carbamoyloxyalkylcarbonsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung
DD121507B1 (de) * 1975-09-29 1989-11-29 Hans Brachwitz Verfahren zur herstellung von 1-o-acyl-und 1-0-alkyl-2-halogenpropandiol-(1,3)
GB1514389A (en) * 1975-12-08 1978-06-14 Abbott Lab Glycerides with antibacterial properties
DE2820892A1 (de) * 1978-05-12 1979-11-22 Nattermann A & Cie Neue strukturanaloga von glyveriden und verfahren zu deren herstellung
US4551532A (en) * 1980-05-08 1985-11-05 Takeda Chemical Industries, Ltd. Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity
EP0054715A3 (de) * 1980-12-18 1982-09-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Propionsäureester, Herstellung dieser Verbindungen, Unkrautbekämpfungsmittel, die diese Verbindungen als Wirkstoffe enthalten, sowie Verwendung solcher Verbindungen und Mittel zur Bekämpfung von Unkräutern
US4493832A (en) * 1981-07-03 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
JPS58192825A (ja) * 1982-05-06 1983-11-10 Takeda Chem Ind Ltd グリセロール誘導体
EP0094586A3 (en) * 1982-05-13 1984-06-06 Ono Pharmaceutical Co., Ltd. Glycerol derivatives, process for preparing same and pharmaceutical composition containing same
JPS5988447A (ja) * 1982-11-11 1984-05-22 Ono Pharmaceut Co Ltd グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤
JPS60104066A (ja) * 1983-11-10 1985-06-08 Ono Pharmaceut Co Ltd グリセリン誘導体

Also Published As

Publication number Publication date
EP0147768A2 (de) 1985-07-10
DK514284A (da) 1985-07-01
ES8701138A1 (es) 1986-11-16
HUT37112A (en) 1985-11-28
MC1639A1 (fr) 1986-01-09
EP0147768B1 (de) 1989-02-08
DK160818B (da) 1991-04-22
DE3476661D1 (en) 1989-03-16
HU195775B (en) 1988-07-28
FI82686B (fi) 1990-12-31
PH21482A (en) 1987-10-28
FI844332L (fi) 1985-07-01
ES8603374A1 (es) 1986-01-01
PT79783A (en) 1985-01-01
IL73920A0 (en) 1985-03-31
FI844332A0 (fi) 1984-11-05
CA1266476A (en) 1990-03-06
ES539136A0 (es) 1986-01-01
EP0147768A3 (en) 1985-10-09
ES547020A0 (es) 1986-11-16
US4731373A (en) 1988-03-15
NO165192C (no) 1991-01-09
NZ210633A (en) 1988-08-30
DK200590A (da) 1990-08-21
AU571625B2 (en) 1988-04-21
NO165192B (no) 1990-10-01
FI82686C (fi) 1991-04-10
AU3719684A (en) 1985-07-04
NO844635L (no) 1985-07-01
PT79783B (en) 1987-01-05
DK514284D0 (da) 1984-10-26
DK160818C (da) 1991-10-07
DK200590D0 (da) 1990-08-21

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