IL72208A - Aryl and heteroaryl(7-(aryl and heteroaryl)pyrazolo-(1,5-a)pyrimidin-3-yl)methanones,their preparation and pharmaceutical compositions containing them - Google Patents
Aryl and heteroaryl(7-(aryl and heteroaryl)pyrazolo-(1,5-a)pyrimidin-3-yl)methanones,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL72208A IL72208A IL72208A IL7220884A IL72208A IL 72208 A IL72208 A IL 72208A IL 72208 A IL72208 A IL 72208A IL 7220884 A IL7220884 A IL 7220884A IL 72208 A IL72208 A IL 72208A
- Authority
- IL
- Israel
- Prior art keywords
- heteroaryl
- aryl
- methanones
- pyrazolo
- pyrimidin
- Prior art date
Links
- 125000001072 heteroaryl group Chemical group 0.000 title abstract 4
- 125000003118 aryl group Chemical group 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 230000004799 sedative–hypnotic effect Effects 0.000 abstract 1
- 229940125706 skeletal muscle relaxant agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50696683A | 1983-06-23 | 1983-06-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL72208A0 IL72208A0 (en) | 1984-10-31 |
| IL72208A true IL72208A (en) | 1987-11-30 |
Family
ID=24016730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72208A IL72208A (en) | 1983-06-23 | 1984-06-22 | Aryl and heteroaryl(7-(aryl and heteroaryl)pyrazolo-(1,5-a)pyrimidin-3-yl)methanones,their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0129847B1 (de) |
| JP (1) | JPS6019788A (de) |
| KR (1) | KR900001886B1 (de) |
| AT (1) | ATE53391T1 (de) |
| AU (1) | AU568656B2 (de) |
| CA (1) | CA1233174A (de) |
| DD (1) | DD228257A5 (de) |
| DE (2) | DE3422844A1 (de) |
| DK (1) | DK307184A (de) |
| ES (1) | ES8505958A1 (de) |
| HK (1) | HK91592A (de) |
| HU (1) | HUT37620A (de) |
| IE (1) | IE58012B1 (de) |
| IL (1) | IL72208A (de) |
| NZ (1) | NZ208554A (de) |
| PH (1) | PH21523A (de) |
| ZA (1) | ZA844776B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4626538A (en) * | 1983-06-23 | 1986-12-02 | American Cyanamid Company | [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines |
| DE3689294T2 (de) * | 1985-05-13 | 1994-06-09 | American Cyanamid Co | [7-(3-Disubstituierte Amino)phenyl]pyrazolo[1,5-a]-pyrimidine. |
| JPS61223072A (ja) * | 1986-02-21 | 1986-10-03 | Canon Inc | インクジエツト記録方法 |
| US4847256A (en) * | 1986-10-16 | 1989-07-11 | American Cyanamid Company | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines |
| EP0264773A1 (de) * | 1986-10-16 | 1988-04-27 | American Cyanamid Company | 4,5-Dihydro- und 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidine |
| FI864570A0 (fi) * | 1986-11-11 | 1986-11-11 | Farmos Oy | Terapeutiskt anvaendbar foerening. |
| US5714607A (en) * | 1995-12-01 | 1998-02-03 | American Cyanamid Company | Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide |
| AU4203500A (en) | 1999-04-06 | 2000-10-23 | Du Pont Pharmaceuticals Company | Pyrazolopyrimidines as crf antagonists |
| US6472528B1 (en) * | 1999-08-10 | 2002-10-29 | Neurocrine Biosciences, Inc. | Synthesis of substituted pyrazolopyrimidines |
| KR20020035585A (ko) * | 1999-09-02 | 2002-05-11 | 추후기재 | Ｎ-메틸-Ｎ-(3-(3-[2-티에닐카보닐]-피라졸-[1,5-α]-피리미딘-7-일)페닐)아세트아미드의 다형체 및 이와 관련된조성물과 방법 |
| WO2004110454A1 (ja) * | 2003-06-13 | 2004-12-23 | Ishihara Sangyo Kaisha, Ltd. | アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物 |
| ES2222813B1 (es) * | 2003-07-24 | 2005-12-16 | Ferrer Internacional, S.A. | N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados. |
| ES2222814B1 (es) * | 2003-07-24 | 2005-12-01 | Ferrer Internacional, S.A. | 3-nitro-pirazolo(1,5-a)pirimidinas 7-sustituidas y composiciones y metodos relacionados. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE792533A (fr) * | 1971-12-09 | 1973-06-08 | Int Chem & Nuclear Corp | Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation |
| US4093617A (en) * | 1974-11-12 | 1978-06-06 | Icn Pharmaceuticals, Inc. | 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines |
| US4178449A (en) * | 1978-04-17 | 1979-12-11 | American Cyanamid Company | Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines |
| US4236005A (en) * | 1979-07-02 | 1980-11-25 | American Cyanamid Company | Imidazo[1,5-a]pyrimidines |
| ZA803591B (en) * | 1979-07-09 | 1981-06-24 | American Cyanamid Co | Substituted pyrazolo(1,5-a)pyrimidines |
| US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
-
1984
- 1984-06-18 NZ NZ208554A patent/NZ208554A/en unknown
- 1984-06-20 DE DE19843422844 patent/DE3422844A1/de not_active Ceased
- 1984-06-20 EP EP84107103A patent/EP0129847B1/de not_active Expired - Lifetime
- 1984-06-20 AT AT84107103T patent/ATE53391T1/de active
- 1984-06-20 DE DE8484107103T patent/DE3482419D1/de not_active Expired - Fee Related
- 1984-06-21 DD DD84264398A patent/DD228257A5/de unknown
- 1984-06-21 PH PH30865A patent/PH21523A/en unknown
- 1984-06-21 CA CA000457122A patent/CA1233174A/en not_active Expired
- 1984-06-22 IE IE158084A patent/IE58012B1/en not_active IP Right Cessation
- 1984-06-22 AU AU29770/84A patent/AU568656B2/en not_active Ceased
- 1984-06-22 KR KR1019840003544A patent/KR900001886B1/ko not_active Expired
- 1984-06-22 HU HU842438A patent/HUT37620A/hu unknown
- 1984-06-22 DK DK307184A patent/DK307184A/da not_active Application Discontinuation
- 1984-06-22 ES ES533654A patent/ES8505958A1/es not_active Expired
- 1984-06-22 IL IL72208A patent/IL72208A/xx not_active IP Right Cessation
- 1984-06-22 ZA ZA844776A patent/ZA844776B/xx unknown
- 1984-06-23 JP JP59129909A patent/JPS6019788A/ja active Granted
-
1992
- 1992-11-19 HK HK915/92A patent/HK91592A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0531551B2 (de) | 1993-05-12 |
| DE3482419D1 (de) | 1990-07-12 |
| HUT37620A (en) | 1986-01-23 |
| KR900001886B1 (ko) | 1990-03-26 |
| AU2977084A (en) | 1985-01-03 |
| DK307184D0 (da) | 1984-06-22 |
| IE841580L (en) | 1984-12-23 |
| IL72208A0 (en) | 1984-10-31 |
| AU568656B2 (en) | 1988-01-07 |
| CA1233174A (en) | 1988-02-23 |
| NZ208554A (en) | 1987-06-30 |
| IE58012B1 (en) | 1993-06-16 |
| ES533654A0 (es) | 1985-07-01 |
| ZA844776B (en) | 1985-02-27 |
| JPS6019788A (ja) | 1985-01-31 |
| PH21523A (en) | 1987-11-16 |
| EP0129847A3 (en) | 1987-05-20 |
| DK307184A (da) | 1984-12-24 |
| ES8505958A1 (es) | 1985-07-01 |
| EP0129847A2 (de) | 1985-01-02 |
| EP0129847B1 (de) | 1990-06-06 |
| HK91592A (en) | 1992-11-27 |
| KR850000443A (ko) | 1985-02-27 |
| ATE53391T1 (de) | 1990-06-15 |
| DE3422844A1 (de) | 1985-01-17 |
| DD228257A5 (de) | 1985-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |