ATE53391T1 - Aryl- und heteroaryl(7-(aryl- und heteroaryl)pyrazolo-(1,5-a)-pyrimidin-3-yl)ketone. - Google Patents

Aryl- und heteroaryl(7-(aryl- und heteroaryl)pyrazolo-(1,5-a)-pyrimidin-3-yl)ketone.

Info

Publication number
ATE53391T1
ATE53391T1 AT84107103T AT84107103T ATE53391T1 AT E53391 T1 ATE53391 T1 AT E53391T1 AT 84107103 T AT84107103 T AT 84107103T AT 84107103 T AT84107103 T AT 84107103T AT E53391 T1 ATE53391 T1 AT E53391T1
Authority
AT
Austria
Prior art keywords
heteroaryl
aryl
pyrazolo
pyrimidin
ketones
Prior art date
Application number
AT84107103T
Other languages
English (en)
Inventor
John Paul Dusza
Andrew Stephen Tomcufcik
Jay Donald Albright
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE53391T1 publication Critical patent/ATE53391T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT84107103T 1983-06-23 1984-06-20 Aryl- und heteroaryl(7-(aryl- und heteroaryl)pyrazolo-(1,5-a)-pyrimidin-3-yl)ketone. ATE53391T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50696683A 1983-06-23 1983-06-23
EP84107103A EP0129847B1 (de) 1983-06-23 1984-06-20 Aryl- und Heteroaryl(7-(aryl- und heteroaryl)-pyrazolo-(1,5-a)-pyrimidin-3-yl)ketone

Publications (1)

Publication Number Publication Date
ATE53391T1 true ATE53391T1 (de) 1990-06-15

Family

ID=24016730

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84107103T ATE53391T1 (de) 1983-06-23 1984-06-20 Aryl- und heteroaryl(7-(aryl- und heteroaryl)pyrazolo-(1,5-a)-pyrimidin-3-yl)ketone.

Country Status (17)

Country Link
EP (1) EP0129847B1 (de)
JP (1) JPS6019788A (de)
KR (1) KR900001886B1 (de)
AT (1) ATE53391T1 (de)
AU (1) AU568656B2 (de)
CA (1) CA1233174A (de)
DD (1) DD228257A5 (de)
DE (2) DE3422844A1 (de)
DK (1) DK307184A (de)
ES (1) ES533654A0 (de)
HK (1) HK91592A (de)
HU (1) HUT37620A (de)
IE (1) IE58012B1 (de)
IL (1) IL72208A (de)
NZ (1) NZ208554A (de)
PH (1) PH21523A (de)
ZA (1) ZA844776B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626538A (en) * 1983-06-23 1986-12-02 American Cyanamid Company [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
DE3689294T2 (de) * 1985-05-13 1994-06-09 American Cyanamid Co [7-(3-Disubstituierte Amino)phenyl]pyrazolo[1,5-a]-pyrimidine.
JPS61223072A (ja) * 1986-02-21 1986-10-03 Canon Inc インクジエツト記録方法
EP0264773A1 (de) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-Dihydro- und 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidine
US4847256A (en) * 1986-10-16 1989-07-11 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines
FI864570A0 (fi) * 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
US5714607A (en) * 1995-12-01 1998-02-03 American Cyanamid Company Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
WO2000059908A2 (en) * 1999-04-06 2000-10-12 Du Pont Pharmaceuticals Company Pyrazolopyrimidines as crf antagonists
US6472528B1 (en) * 1999-08-10 2002-10-29 Neurocrine Biosciences, Inc. Synthesis of substituted pyrazolopyrimidines
AP1631A (en) * 1999-09-02 2006-07-12 Neurocrine Biosciences Inc Polymorphs of N-methyl-N- (3- {3- [2-thienylcarbonyl] -pyrazol- [1,5-?] -pyrimidin-7-yl} phenyl) acetamide and compositions and methods related thereto.
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
ES2222813B1 (es) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
ES2222814B1 (es) * 2003-07-24 2005-12-01 Ferrer Internacional, S.A. 3-nitro-pirazolo(1,5-a)pirimidinas 7-sustituidas y composiciones y metodos relacionados.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792533A (fr) * 1971-12-09 1973-06-08 Int Chem & Nuclear Corp Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation
US4093617A (en) * 1974-11-12 1978-06-06 Icn Pharmaceuticals, Inc. 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
ZA803591B (en) * 1979-07-09 1981-06-24 American Cyanamid Co Substituted pyrazolo(1,5-a)pyrimidines

Also Published As

Publication number Publication date
AU568656B2 (en) 1988-01-07
CA1233174A (en) 1988-02-23
JPH0531551B2 (de) 1993-05-12
ZA844776B (en) 1985-02-27
EP0129847A3 (en) 1987-05-20
DD228257A5 (de) 1985-10-09
NZ208554A (en) 1987-06-30
KR900001886B1 (ko) 1990-03-26
DK307184A (da) 1984-12-24
DK307184D0 (da) 1984-06-22
IL72208A (en) 1987-11-30
DE3482419D1 (de) 1990-07-12
JPS6019788A (ja) 1985-01-31
EP0129847A2 (de) 1985-01-02
IE58012B1 (en) 1993-06-16
HUT37620A (en) 1986-01-23
IE841580L (en) 1984-12-23
IL72208A0 (en) 1984-10-31
DE3422844A1 (de) 1985-01-17
PH21523A (en) 1987-11-16
ES8505958A1 (es) 1985-07-01
AU2977084A (en) 1985-01-03
EP0129847B1 (de) 1990-06-06
ES533654A0 (es) 1985-07-01
KR850000443A (ko) 1985-02-27
HK91592A (en) 1992-11-27

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