IL69683A0 - Isoquinoline derivatives,a process for their preparation,pharmaceutical formulations based on these compounds and the use thereof - Google Patents
Isoquinoline derivatives,a process for their preparation,pharmaceutical formulations based on these compounds and the use thereofInfo
- Publication number
- IL69683A0 IL69683A0 IL69683A IL6968383A IL69683A0 IL 69683 A0 IL69683 A0 IL 69683A0 IL 69683 A IL69683 A IL 69683A IL 6968383 A IL6968383 A IL 6968383A IL 69683 A0 IL69683 A0 IL 69683A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- preparation
- pharmaceutical formulations
- formulations based
- isoquinoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823233424 DE3233424A1 (de) | 1982-09-09 | 1982-09-09 | Isochinolinderivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL69683A0 true IL69683A0 (en) | 1983-12-30 |
Family
ID=6172780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69683A IL69683A0 (en) | 1982-09-09 | 1983-09-07 | Isoquinoline derivatives,a process for their preparation,pharmaceutical formulations based on these compounds and the use thereof |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4673682A (hu) |
| EP (1) | EP0105210B1 (hu) |
| JP (1) | JPS5967270A (hu) |
| KR (1) | KR840006206A (hu) |
| AT (1) | ATE25679T1 (hu) |
| AU (1) | AU1891683A (hu) |
| CA (1) | CA1211445A (hu) |
| DE (2) | DE3233424A1 (hu) |
| DK (1) | DK408083A (hu) |
| ES (1) | ES8404852A1 (hu) |
| FI (1) | FI833200A (hu) |
| GR (1) | GR79382B (hu) |
| HU (1) | HU191094B (hu) |
| IL (1) | IL69683A0 (hu) |
| NO (1) | NO833217L (hu) |
| NZ (1) | NZ205513A (hu) |
| PH (1) | PH18186A (hu) |
| PT (1) | PT77309B (hu) |
| ZA (1) | ZA836663B (hu) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956371A (en) * | 1989-09-19 | 1990-09-11 | Euroceltique, S.A. | Substituted isoquinolines and methods of using same |
| ATE198328T1 (de) * | 1992-09-28 | 2001-01-15 | Hoechst Ag | Antiarrhythmische und cardioprotektive substituierte 1(2h)-isochinoline, verfahren zu deren herstellung, diese enthaltende arzneimittel und ihre anwendung für die herstellung eines arzneimittels zur behandlung von herzinsuffizienzen |
| SI1644336T1 (sl) | 2003-06-06 | 2011-06-30 | Fibrogen Inc | Heteroarilne spojine, ki vsebujejo duĺ ik in njihova uporaba pri zviĺ anju endogenega eritropoetina |
| US7928120B2 (en) | 2006-01-27 | 2011-04-19 | Fibrogen, Inc. | Cyanoisoquinoline compounds and methods of use thereof |
| CN101460497A (zh) * | 2006-04-04 | 2009-06-17 | 菲布罗根有限公司 | 作为hif调节剂的吡咯并吡啶和噻唑并吡啶化合物 |
| EP2370422B1 (en) | 2008-11-14 | 2019-06-05 | Fibrogen, Inc. | Thiochromene derivatives as hif hydroxylase inhibitors |
| CN104470899B (zh) | 2012-03-09 | 2017-12-26 | 菲布罗根有限公司 | 作为hif羟化酶抑制剂的4‑羟基‑异喹啉化合物 |
| CN107501177B (zh) | 2012-07-16 | 2018-12-07 | 菲布罗根有限公司 | 脯氨酰羟化酶抑制剂的晶体形态 |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| IN2015KN00265A (hu) | 2012-07-16 | 2015-06-12 | Fibrogen Inc | |
| CA2899024C (en) | 2013-01-24 | 2022-01-04 | Fibrogen, Inc. | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2054482B1 (hu) * | 1969-07-11 | 1973-06-08 | Anvar | |
| FR2424270A1 (fr) * | 1978-04-24 | 1979-11-23 | Rhone Poulenc Ind | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
| DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1982
- 1982-09-09 DE DE19823233424 patent/DE3233424A1/de not_active Withdrawn
-
1983
- 1983-09-03 DE DE8383108697T patent/DE3369983D1/de not_active Expired
- 1983-09-03 EP EP83108697A patent/EP0105210B1/de not_active Expired
- 1983-09-03 AT AT83108697T patent/ATE25679T1/de not_active IP Right Cessation
- 1983-09-07 GR GR72399A patent/GR79382B/el unknown
- 1983-09-07 IL IL69683A patent/IL69683A0/xx unknown
- 1983-09-07 PH PH29505A patent/PH18186A/en unknown
- 1983-09-07 NZ NZ205513A patent/NZ205513A/en unknown
- 1983-09-07 US US06/530,000 patent/US4673682A/en not_active Expired - Fee Related
- 1983-09-07 FI FI833200A patent/FI833200A/fi not_active Application Discontinuation
- 1983-09-07 ES ES525441A patent/ES8404852A1/es not_active Expired
- 1983-09-07 KR KR1019830004199A patent/KR840006206A/ko not_active Application Discontinuation
- 1983-09-08 NO NO833217A patent/NO833217L/no unknown
- 1983-09-08 PT PT77309A patent/PT77309B/pt unknown
- 1983-09-08 AU AU18916/83A patent/AU1891683A/en not_active Abandoned
- 1983-09-08 DK DK408083A patent/DK408083A/da not_active Application Discontinuation
- 1983-09-08 JP JP58164274A patent/JPS5967270A/ja active Pending
- 1983-09-08 HU HU833134A patent/HU191094B/hu unknown
- 1983-09-08 CA CA000436316A patent/CA1211445A/en not_active Expired
- 1983-09-08 ZA ZA836663A patent/ZA836663B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI833200A0 (fi) | 1983-09-07 |
| US4673682A (en) | 1987-06-16 |
| PH18186A (en) | 1985-04-12 |
| GR79382B (hu) | 1984-10-22 |
| ATE25679T1 (de) | 1987-03-15 |
| ES525441A0 (es) | 1984-05-16 |
| HU191094B (en) | 1987-01-28 |
| ZA836663B (en) | 1984-04-25 |
| DK408083A (da) | 1984-03-10 |
| EP0105210B1 (de) | 1987-03-04 |
| KR840006206A (ko) | 1984-11-22 |
| AU1891683A (en) | 1984-03-15 |
| PT77309B (de) | 1986-04-18 |
| ES8404852A1 (es) | 1984-05-16 |
| NZ205513A (en) | 1986-05-09 |
| NO833217L (no) | 1984-03-12 |
| DE3369983D1 (en) | 1987-04-09 |
| JPS5967270A (ja) | 1984-04-16 |
| PT77309A (de) | 1983-10-01 |
| FI833200A (fi) | 1984-03-10 |
| EP0105210A2 (de) | 1984-04-11 |
| DK408083D0 (da) | 1983-09-08 |
| DE3233424A1 (de) | 1984-03-15 |
| EP0105210A3 (en) | 1984-10-10 |
| CA1211445A (en) | 1986-09-16 |
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