IL69086A0 - Tylosin derivatives,processes for their production and pharmaceutical compositions containing them - Google Patents
Tylosin derivatives,processes for their production and pharmaceutical compositions containing themInfo
- Publication number
- IL69086A0 IL69086A0 IL69086A IL6908683A IL69086A0 IL 69086 A0 IL69086 A0 IL 69086A0 IL 69086 A IL69086 A IL 69086A IL 6908683 A IL6908683 A IL 6908683A IL 69086 A0 IL69086 A0 IL 69086A0
- Authority
- IL
- Israel
- Prior art keywords
- acyl
- processes
- pharmaceutical compositions
- compositions containing
- hydrogen
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 title 1
- 125000002252 acyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 2
- 125000005997 bromomethyl group Chemical group 0.000 abstract 2
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 abstract 2
- 125000004216 fluoromethyl group Chemical group [H]C([H])(F)* 0.000 abstract 2
- -1 iodomethyl Chemical group 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/393,901 US4436729A (en) | 1982-06-30 | 1982-06-30 | 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL69086A0 true IL69086A0 (en) | 1983-10-31 |
Family
ID=23556716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69086A IL69086A0 (en) | 1982-06-30 | 1983-06-27 | Tylosin derivatives,processes for their production and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4436729A (ref) |
| EP (1) | EP0097925B1 (ref) |
| JP (1) | JPS5913798A (ref) |
| AT (1) | ATE24914T1 (ref) |
| AU (1) | AU555788B2 (ref) |
| CA (1) | CA1241952A (ref) |
| DE (1) | DE3369142D1 (ref) |
| DK (1) | DK297883D0 (ref) |
| GR (1) | GR77522B (ref) |
| HU (1) | HU194270B (ref) |
| IE (1) | IE55267B1 (ref) |
| IL (1) | IL69086A0 (ref) |
| NZ (1) | NZ204718A (ref) |
| PH (1) | PH18303A (ref) |
| PT (1) | PT76936B (ref) |
| ZA (1) | ZA834692B (ref) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4452784A (en) * | 1982-07-19 | 1984-06-05 | Eli Lilly And Company | C-23-Modified derivatives of DMT |
| US4820695A (en) * | 1982-09-13 | 1989-04-11 | Eli Lilly And Company | C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics |
| US4604380A (en) * | 1985-01-18 | 1986-08-05 | Eli Lilly And Company | C-23-substituted mycaminosyltylonolide compounds, pharmaceutical compositions and methods of use |
| US4851518A (en) * | 1985-12-23 | 1989-07-25 | Schering Corporation | Di and tri-O-acetyl-"O-iso-valeryl-23-O-demycinosyl tylosins, hydrazone derivatives thereof and processes for their preparation |
| US4920103A (en) * | 1986-09-29 | 1990-04-24 | Eli Lilly And Company | Modifications of mycinose and 3-O-demethylmycinose in tylosin-type macrolides |
| US4919804A (en) * | 1988-03-01 | 1990-04-24 | University Of Florida | Ultrasound driven synthesis of reversed and normal phase stationary phases for liquid chromatography |
| US4933439A (en) * | 1988-06-21 | 1990-06-12 | Sanraku Incorporated | Tylosin derivatives and processes for producing the same |
| US6753415B2 (en) * | 2002-04-19 | 2004-06-22 | Enanta Pharmaceuticals, Inc. | 23-O-substituted 5-O-mycaminosyltylonide derivatives |
| US6710034B2 (en) | 2002-04-19 | 2004-03-23 | Enanta Pharmaceuticals, Inc. | 5-O-mycaminosyltylonide derivatives |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH630391A5 (en) * | 1975-02-28 | 1982-06-15 | Scherico Ltd | Process for preparing derivatives of rosaramicin |
| ZA813578B (en) * | 1980-06-12 | 1983-01-26 | Lilly Co Eli | Macrolide antibiotics |
| US4321361A (en) * | 1980-06-12 | 1982-03-23 | Eli Lilly And Company | Demycinosyltylosin and process for its production |
| US4334019A (en) | 1980-06-12 | 1982-06-08 | Eli Lilly And Company | Process for producing de(mycinosyloxy)tylosin |
| US4279896A (en) | 1980-06-23 | 1981-07-21 | Schering Corporation | Novel 20-imino macrolide antibacterial agents |
| US4438109A (en) * | 1980-07-25 | 1984-03-20 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Tylosin derivatives |
| US4299953A (en) | 1980-07-29 | 1981-11-10 | Eli Lilly And Company | Mycarosyltylactone |
| US4341770A (en) * | 1981-04-20 | 1982-07-27 | Eli Lilly And Company | Method of controlling ureaplasma infections |
| AU551142B2 (en) * | 1981-07-09 | 1986-04-17 | Zaidan Hojin Biseibutsu Kagaku Kenkyukai | Tylosin derivatives |
| JPS58219197A (ja) * | 1982-06-15 | 1983-12-20 | Sanraku Inc | マクロライド系抗生物質の誘導体 |
| US4452784A (en) * | 1982-07-19 | 1984-06-05 | Eli Lilly And Company | C-23-Modified derivatives of DMT |
-
1982
- 1982-06-30 US US06/393,901 patent/US4436729A/en not_active Expired - Fee Related
-
1983
- 1983-06-23 EP EP83106167A patent/EP0097925B1/en not_active Expired
- 1983-06-23 AT AT83106167T patent/ATE24914T1/de not_active IP Right Cessation
- 1983-06-23 DE DE8383106167T patent/DE3369142D1/de not_active Expired
- 1983-06-27 IE IE1491/83A patent/IE55267B1/en unknown
- 1983-06-27 NZ NZ204718A patent/NZ204718A/en unknown
- 1983-06-27 PT PT76936A patent/PT76936B/pt unknown
- 1983-06-27 AU AU16306/83A patent/AU555788B2/en not_active Ceased
- 1983-06-27 PH PH29123A patent/PH18303A/en unknown
- 1983-06-27 ZA ZA834692A patent/ZA834692B/xx unknown
- 1983-06-27 IL IL69086A patent/IL69086A0/xx unknown
- 1983-06-28 GR GR71783A patent/GR77522B/el unknown
- 1983-06-28 DK DK2978/83A patent/DK297883D0/da not_active Application Discontinuation
- 1983-06-28 CA CA000431296A patent/CA1241952A/en not_active Expired
- 1983-06-28 JP JP58116819A patent/JPS5913798A/ja active Pending
- 1983-06-29 HU HU832353A patent/HU194270B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT76936B (en) | 1986-04-09 |
| PT76936A (en) | 1983-07-01 |
| IE831491L (en) | 1983-12-30 |
| DE3369142D1 (en) | 1987-02-19 |
| DK297883D0 (da) | 1983-06-28 |
| AU555788B2 (en) | 1986-10-09 |
| ATE24914T1 (de) | 1987-01-15 |
| CA1241952A (en) | 1988-09-13 |
| AU1630683A (en) | 1984-01-05 |
| PH18303A (en) | 1985-05-29 |
| EP0097925A1 (en) | 1984-01-11 |
| JPS5913798A (ja) | 1984-01-24 |
| ZA834692B (en) | 1984-03-28 |
| HU194270B (en) | 1988-01-28 |
| EP0097925B1 (en) | 1987-01-14 |
| GR77522B (ref) | 1984-09-24 |
| IE55267B1 (en) | 1990-07-18 |
| NZ204718A (en) | 1986-05-09 |
| US4436729A (en) | 1984-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3369142D1 (en) | Tylosin derivatives, processes for their production and pharmaceutical compositions containing them | |
| ES8401082A1 (es) | Un procedimiento de preparacion de nuevas cefalosporinas. | |
| PH24176A (en) | New bicyclic compounds,process for preparation thereof and pharmaceutical composition comprising the same | |
| ES460286A1 (es) | Un procedimiento de preparacion de espiro(1,3-dioxolan-4,3) quinuclidina. | |
| GR80832B (en) | Cyclic ethers | |
| DE3565104D1 (en) | Thiadiazine compound, process for its preparation and pharmaceutical compositions containing it | |
| PT78991A (en) | Process for preparing a novel antibiotic and of compositions containing the same | |
| ES8707961A1 (es) | Un procedimiento para preparar nuevos compuestos de 14-oxa-1, 11-diazatetraciclo (7.4.1.0-2,7.o-10,12)tetradeca-2,4,6-trieno. | |
| ES8300685A1 (es) | Procedimiento para la produccion de pentapeptidos | |
| SG12188G (en) | New derivatives of cephalosporins substituted in 3 position by a thiomethyl heterocycle group;process for preparing these compounds and pharmaceutical compositions containing them | |
| HUT34744A (en) | Process for producing new imidazolinone derivatives and pharmaceutical compositions containing the | |
| MY101765A (en) | Benzopyran derivatives, compositions containing them and processes for their production | |
| ATE34740T1 (de) | (bis(hydroxymethyl)methyl)-isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten. | |
| IL65213A (en) | 1,4-benzoxazine derivatives,cyclopent(b)(1,4)oxazine derivatives,their preparation and pharmaceutical compositions containing them | |
| FR2429790A1 (fr) | Synthese totale de la substance utero-evacuante d,l-zoapatanol, derivee de la plante zoapatle | |
| ES8400434A1 (es) | "un procedimiento para preparar 1,2-dihidropirido(3,4-b)pirazinas". | |
| HUT57221A (en) | Process for producing pyrrolo(2,1-b)thiazol derivatives and pahrmaceutical compositions contiaining them as active components | |
| FR2429789A1 (fr) | Synthese totale de la substance utero-evacuante d,l-zoapatanol, derivee de la plante zoapatle | |
| IL64218A (en) | Heterobicyclic hydroxyimidates and thiolhydroximidates and carbamate ester derivatives thereof,their preparation and arthropodicidal and nematocidal compositions containing them | |
| EP0273357A3 (en) | Fluorine-containing macrolide compounds, pharmaceutical compositions comprising the same and their use for the manufacture of medicaments | |
| FR2432505A1 (fr) | Nouveaux sels de 5-iodo-3-nitro-4-hydroxybenzonitrile, leur preparation et compositions qui les contiennent | |
| JPS5262257A (en) | Preparation of novel bicyclo 4,3,0 nonane derivatives | |
| ES472335A1 (es) | Un procedimiento para la preparacion de eteres del acido clavulanico | |
| PT84067A (en) | Novel pregnane derivatives process for their preparation and pharmaceutical compositions containing same | |
| FR2400032A1 (en) | 5-Hydroxy-macro:lactone derivs. and glucopyranosyl ether(s) - intermediates for macrolide antibiotics |