IL67675A - (1-alkyl-5-(o-halophenyl)-6-halo-2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-7-yl)urea derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents
(1-alkyl-5-(o-halophenyl)-6-halo-2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-7-yl)urea derivatives,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL67675A IL67675A IL67675A IL6767583A IL67675A IL 67675 A IL67675 A IL 67675A IL 67675 A IL67675 A IL 67675A IL 6767583 A IL6767583 A IL 6767583A IL 67675 A IL67675 A IL 67675A
- Authority
- IL
- Israel
- Prior art keywords
- halophenyl
- benzodiazepine
- dihydro
- halo
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH31382 | 1982-01-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL67675A0 IL67675A0 (en) | 1983-05-15 |
| IL67675A true IL67675A (en) | 1986-01-31 |
Family
ID=4184157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67675A IL67675A (en) | 1982-01-19 | 1983-01-13 | (1-alkyl-5-(o-halophenyl)-6-halo-2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-7-yl)urea derivatives,their manufacture and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4474777A (fi) |
| EP (1) | EP0084357A1 (fi) |
| JP (1) | JPS58124774A (fi) |
| KR (1) | KR840003243A (fi) |
| AU (1) | AU1031383A (fi) |
| CA (1) | CA1202023A (fi) |
| DK (1) | DK19383A (fi) |
| ES (1) | ES8402582A1 (fi) |
| FI (1) | FI830134L (fi) |
| GR (1) | GR77189B (fi) |
| HU (1) | HU191041B (fi) |
| IL (1) | IL67675A (fi) |
| MC (1) | MC1502A1 (fi) |
| NO (1) | NO830161L (fi) |
| NZ (1) | NZ203005A (fi) |
| PH (1) | PH17992A (fi) |
| PT (1) | PT76108B (fi) |
| ZA (1) | ZA83207B (fi) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4684646A (en) * | 1984-06-26 | 1987-08-04 | Merck & Co., Inc. | 2-acylaminomethyl-1,4-benzodiazepine derivatives as CCK-antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4251443A (en) * | 1979-08-02 | 1981-02-17 | Hoffmann-La Roche Inc. | Benzodiazepine derivatives |
| US4299767A (en) * | 1978-08-11 | 1981-11-10 | Hoffmann-La Roche Inc. | Benzodiazepine derivatives |
| CA1114373A (en) * | 1978-08-11 | 1981-12-15 | Albert E. Fischli | Benzodiazepine derivatives |
-
1982
- 1982-11-22 CA CA000416049A patent/CA1202023A/en not_active Expired
- 1982-12-17 US US06/450,603 patent/US4474777A/en not_active Expired - Lifetime
-
1983
- 1983-01-12 PH PH28379A patent/PH17992A/en unknown
- 1983-01-12 NZ NZ203005A patent/NZ203005A/en unknown
- 1983-01-12 ZA ZA83207A patent/ZA83207B/xx unknown
- 1983-01-12 AU AU10313/83A patent/AU1031383A/en not_active Abandoned
- 1983-01-13 IL IL67675A patent/IL67675A/xx unknown
- 1983-01-14 FI FI830134A patent/FI830134L/fi not_active Application Discontinuation
- 1983-01-14 EP EP83100295A patent/EP0084357A1/de not_active Ceased
- 1983-01-17 JP JP58004318A patent/JPS58124774A/ja active Pending
- 1983-01-17 GR GR70272A patent/GR77189B/el unknown
- 1983-01-17 MC MC831617A patent/MC1502A1/xx unknown
- 1983-01-17 HU HU83135A patent/HU191041B/hu unknown
- 1983-01-18 PT PT76108A patent/PT76108B/pt unknown
- 1983-01-18 DK DK19383A patent/DK19383A/da not_active Application Discontinuation
- 1983-01-18 ES ES519083A patent/ES8402582A1/es not_active Expired
- 1983-01-18 NO NO830161A patent/NO830161L/no unknown
- 1983-01-19 KR KR1019830000187A patent/KR840003243A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI830134A0 (fi) | 1983-01-14 |
| FI830134L (fi) | 1983-07-20 |
| JPS58124774A (ja) | 1983-07-25 |
| MC1502A1 (fr) | 1983-11-17 |
| NZ203005A (en) | 1986-01-24 |
| DK19383A (da) | 1983-07-20 |
| US4474777A (en) | 1984-10-02 |
| DK19383D0 (da) | 1983-01-18 |
| CA1202023A (en) | 1986-03-18 |
| PT76108A (en) | 1983-02-01 |
| ES519083A0 (es) | 1984-03-01 |
| ZA83207B (en) | 1983-10-26 |
| PH17992A (en) | 1985-02-28 |
| GR77189B (fi) | 1984-09-11 |
| PT76108B (en) | 1986-01-24 |
| ES8402582A1 (es) | 1984-03-01 |
| AU1031383A (en) | 1983-07-28 |
| EP0084357A1 (de) | 1983-07-27 |
| IL67675A0 (en) | 1983-05-15 |
| HU191041B (en) | 1986-12-28 |
| NO830161L (no) | 1983-07-20 |
| KR840003243A (ko) | 1984-08-20 |
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