DK19383D0 - Fremgangsmade til fremstilling af benzodiazepiner, let hydrolyserbare estere eller ethere deraf eller farmaceutisk acceptable salte af disse forbindelser - Google Patents

Fremgangsmade til fremstilling af benzodiazepiner, let hydrolyserbare estere eller ethere deraf eller farmaceutisk acceptable salte af disse forbindelser

Info

Publication number
DK19383D0
DK19383D0 DK0193/83A DK19383A DK19383D0 DK 19383 D0 DK19383 D0 DK 19383D0 DK 0193/83 A DK0193/83 A DK 0193/83A DK 19383 A DK19383 A DK 19383A DK 19383 D0 DK19383 D0 DK 19383D0
Authority
DK
Denmark
Prior art keywords
hydrolysible
benzodiazepines
ethers
esters
compounds
Prior art date
Application number
DK0193/83A
Other languages
English (en)
Other versions
DK19383A (da
Inventor
Jean-Marie Cassal
Albert Eduard Fischli
Andre Szente
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK19383D0 publication Critical patent/DK19383D0/da
Publication of DK19383A publication Critical patent/DK19383A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK19383A 1982-01-19 1983-01-18 Fremgangsmaade til fremstilling af benzodiazepiner, let hydrolyserbare estere eller ethere deraf eller farmaceutisk acceptable salte af disse forbindelser DK19383A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH31382 1982-01-19

Publications (2)

Publication Number Publication Date
DK19383D0 true DK19383D0 (da) 1983-01-18
DK19383A DK19383A (da) 1983-07-20

Family

ID=4184157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19383A DK19383A (da) 1982-01-19 1983-01-18 Fremgangsmaade til fremstilling af benzodiazepiner, let hydrolyserbare estere eller ethere deraf eller farmaceutisk acceptable salte af disse forbindelser

Country Status (18)

Country Link
US (1) US4474777A (da)
EP (1) EP0084357A1 (da)
JP (1) JPS58124774A (da)
KR (1) KR840003243A (da)
AU (1) AU1031383A (da)
CA (1) CA1202023A (da)
DK (1) DK19383A (da)
ES (1) ES8402582A1 (da)
FI (1) FI830134L (da)
GR (1) GR77189B (da)
HU (1) HU191041B (da)
IL (1) IL67675A (da)
MC (1) MC1502A1 (da)
NO (1) NO830161L (da)
NZ (1) NZ203005A (da)
PH (1) PH17992A (da)
PT (1) PT76108B (da)
ZA (1) ZA83207B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684646A (en) * 1984-06-26 1987-08-04 Merck & Co., Inc. 2-acylaminomethyl-1,4-benzodiazepine derivatives as CCK-antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4299767A (en) * 1978-08-11 1981-11-10 Hoffmann-La Roche Inc. Benzodiazepine derivatives
CA1114373A (en) * 1978-08-11 1981-12-15 Albert E. Fischli Benzodiazepine derivatives
US4251443A (en) * 1979-08-02 1981-02-17 Hoffmann-La Roche Inc. Benzodiazepine derivatives

Also Published As

Publication number Publication date
DK19383A (da) 1983-07-20
GR77189B (da) 1984-09-11
ES519083A0 (es) 1984-03-01
NO830161L (no) 1983-07-20
US4474777A (en) 1984-10-02
CA1202023A (en) 1986-03-18
MC1502A1 (fr) 1983-11-17
KR840003243A (ko) 1984-08-20
HU191041B (en) 1986-12-28
PH17992A (en) 1985-02-28
PT76108A (en) 1983-02-01
AU1031383A (en) 1983-07-28
ES8402582A1 (es) 1984-03-01
NZ203005A (en) 1986-01-24
IL67675A (en) 1986-01-31
ZA83207B (en) 1983-10-26
JPS58124774A (ja) 1983-07-25
FI830134A0 (fi) 1983-01-14
EP0084357A1 (de) 1983-07-27
FI830134L (fi) 1983-07-20
IL67675A0 (en) 1983-05-15
PT76108B (en) 1986-01-24

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment