IL66868A - 6-fluoro-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoles,a process for their preparation and pharmaceutical compositions thereof - Google Patents
6-fluoro-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoles,a process for their preparation and pharmaceutical compositions thereofInfo
- Publication number
- IL66868A IL66868A IL66868A IL6686882A IL66868A IL 66868 A IL66868 A IL 66868A IL 66868 A IL66868 A IL 66868A IL 6686882 A IL6686882 A IL 6686882A IL 66868 A IL66868 A IL 66868A
- Authority
- IL
- Israel
- Prior art keywords
- fluoro
- preparation
- heterocyclo
- benzisoxazoles
- propyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/366,245 US4458075A (en) | 1982-04-09 | 1982-04-09 | 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL66868A0 IL66868A0 (en) | 1982-12-31 |
| IL66868A true IL66868A (en) | 1987-07-31 |
Family
ID=23442245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL66868A IL66868A (en) | 1982-04-09 | 1982-09-24 | 6-fluoro-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoles,a process for their preparation and pharmaceutical compositions thereof |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4458075A (es) |
| EP (1) | EP0091512B1 (es) |
| JP (1) | JPS58177981A (es) |
| AT (1) | ATE34172T1 (es) |
| AU (1) | AU560513B2 (es) |
| CA (1) | CA1189858A (es) |
| DE (1) | DE3278472D1 (es) |
| DK (1) | DK474582A (es) |
| ES (1) | ES516828A0 (es) |
| FI (1) | FI823434L (es) |
| GR (1) | GR77705B (es) |
| HU (1) | HU191076B (es) |
| IL (1) | IL66868A (es) |
| NO (1) | NO823557L (es) |
| NZ (1) | NZ202045A (es) |
| PH (1) | PH18365A (es) |
| PT (1) | PT75728B (es) |
| ZA (1) | ZA827814B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894461A (en) * | 1981-04-27 | 1990-01-16 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole |
| US4980365A (en) * | 1987-07-13 | 1990-12-25 | Hoechst-Roussel Pharmaceuticals Inc. | N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents |
| US4861889A (en) * | 1988-03-14 | 1989-08-29 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes |
| US4954511A (en) * | 1988-03-14 | 1990-09-04 | Hoechst-Roussell Pharmaceuticals Inc. | 4-pentafluorophenoxypiperidines |
| US4914204A (en) * | 1988-03-14 | 1990-04-03 | Hoechst-Roussel Pharmaceuticals Incorporated | 4-Pentafluorophenoxypiperidines |
| US5114936A (en) * | 1990-08-23 | 1992-05-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use |
| US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| EP1535912A1 (en) * | 2000-04-28 | 2005-06-01 | Arcadia Pharmaceuticals Inc. | Muscarinic agonists |
| ATE290000T1 (de) * | 2000-04-28 | 2005-03-15 | Acadia Pharm Inc | Muscarinagonisten |
| DE102019103847A1 (de) | 2019-02-15 | 2020-08-20 | Vetron Typical Europe Gmbh | Nähmaschine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4970963A (es) * | 1972-11-09 | 1974-07-09 | ||
| GB1488003A (en) * | 1973-10-23 | 1977-10-05 | Lilly Industries Ltd | 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals |
| FI60390C (fi) * | 1975-03-05 | 1982-01-11 | Sumitomo Chemical Co | Foerfarande foer framstaellning av neuroleptiska butyrofenoner |
| JPS51136666A (en) * | 1975-05-19 | 1976-11-26 | Dainippon Pharmaceut Co Ltd | Process for preparing 3-aminoalkyl-1,2-benzisoxazole derivatives. |
| JPS6043064B2 (ja) * | 1979-11-28 | 1985-09-26 | ウェルファイド株式会社 | 新規イソオキサゾ−ル誘導体 |
-
1982
- 1982-04-09 US US06/366,245 patent/US4458075A/en not_active Expired - Lifetime
- 1982-09-24 IL IL66868A patent/IL66868A/xx unknown
- 1982-09-30 NZ NZ202045A patent/NZ202045A/en unknown
- 1982-10-08 FI FI823434A patent/FI823434L/fi not_active Application Discontinuation
- 1982-10-22 PT PT75728A patent/PT75728B/pt unknown
- 1982-10-22 GR GR69602A patent/GR77705B/el unknown
- 1982-10-23 AT AT82109802T patent/ATE34172T1/de not_active IP Right Cessation
- 1982-10-23 EP EP82109802A patent/EP0091512B1/en not_active Expired
- 1982-10-23 DE DE8282109802T patent/DE3278472D1/de not_active Expired
- 1982-10-26 AU AU89777/82A patent/AU560513B2/en not_active Ceased
- 1982-10-26 ZA ZA827814A patent/ZA827814B/xx unknown
- 1982-10-26 HU HU823416A patent/HU191076B/hu unknown
- 1982-10-26 PH PH28038A patent/PH18365A/en unknown
- 1982-10-26 CA CA000414158A patent/CA1189858A/en not_active Expired
- 1982-10-26 ES ES516828A patent/ES516828A0/es active Granted
- 1982-10-26 JP JP57186908A patent/JPS58177981A/ja active Pending
- 1982-10-26 NO NO823557A patent/NO823557L/no unknown
- 1982-10-26 DK DK474582A patent/DK474582A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0091512A3 (en) | 1984-12-12 |
| GR77705B (es) | 1984-09-25 |
| FI823434A0 (fi) | 1982-10-08 |
| PT75728B (en) | 1985-11-11 |
| ATE34172T1 (de) | 1988-05-15 |
| US4458075A (en) | 1984-07-03 |
| NO823557L (no) | 1983-10-10 |
| DE3278472D1 (en) | 1988-06-16 |
| DK474582A (da) | 1983-10-10 |
| ES8308560A1 (es) | 1983-09-16 |
| PH18365A (en) | 1985-06-13 |
| FI823434L (fi) | 1983-10-10 |
| EP0091512A2 (en) | 1983-10-19 |
| PT75728A (en) | 1982-11-01 |
| NZ202045A (en) | 1986-03-14 |
| CA1189858A (en) | 1985-07-02 |
| HU191076B (en) | 1987-01-28 |
| IL66868A0 (en) | 1982-12-31 |
| ZA827814B (en) | 1983-08-31 |
| EP0091512B1 (en) | 1988-05-11 |
| JPS58177981A (ja) | 1983-10-18 |
| AU560513B2 (en) | 1987-04-09 |
| ES516828A0 (es) | 1983-09-16 |
| AU8977782A (en) | 1983-10-13 |
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| GR77706B (es) | ||
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