IL66650A - Dibenzoxepines and dibenzooxazepines,their preparation and pharmaceutical compositions containing them - Google Patents

Dibenzoxepines and dibenzooxazepines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL66650A
IL66650A IL66650A IL6665082A IL66650A IL 66650 A IL66650 A IL 66650A IL 66650 A IL66650 A IL 66650A IL 6665082 A IL6665082 A IL 6665082A IL 66650 A IL66650 A IL 66650A
Authority
IL
Israel
Prior art keywords
group
lower alkyl
dibenzoxepines
dibenzooxazepines
preparation
Prior art date
Application number
IL66650A
Other languages
English (en)
Other versions
IL66650A0 (en
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of IL66650A0 publication Critical patent/IL66650A0/xx
Publication of IL66650A publication Critical patent/IL66650A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12[b,e]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/18[b, e]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
IL66650A 1981-08-27 1982-08-26 Dibenzoxepines and dibenzooxazepines,their preparation and pharmaceutical compositions containing them IL66650A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8116347A FR2512024A1 (fr) 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
IL66650A0 IL66650A0 (en) 1982-12-31
IL66650A true IL66650A (en) 1985-08-30

Family

ID=9261704

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66650A IL66650A (en) 1981-08-27 1982-08-26 Dibenzoxepines and dibenzooxazepines,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4496557A (id)
EP (1) EP0074304B1 (id)
JP (1) JPS5874673A (id)
AT (1) ATE12497T1 (id)
AU (1) AU8773082A (id)
CA (1) CA1227481A (id)
DE (1) DE3262880D1 (id)
ES (1) ES515232A0 (id)
FR (1) FR2512024A1 (id)
GR (1) GR77595B (id)
IL (1) IL66650A (id)
NZ (1) NZ201740A (id)
PT (1) PT75471B (id)
ZA (1) ZA826252B (id)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
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SE8500273D0 (sv) * 1985-01-22 1985-01-22 Leo Ab Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder
EP0332246A1 (en) * 1988-03-11 1989-09-13 Akzo N.V. Tricyclic amine derivatives
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5006536A (en) * 1989-12-26 1991-04-09 Hoechst-Roussel Pharmaceuticals Inc. Thienobenzoxepins and analgesic compositions thereof
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
US8571289B2 (en) 2002-11-27 2013-10-29 Hologic, Inc. System and method for generating a 2D image from a tomosynthesis data set
US10638994B2 (en) 2002-11-27 2020-05-05 Hologic, Inc. X-ray mammography with tomosynthesis
US7577282B2 (en) 2002-11-27 2009-08-18 Hologic, Inc. Image handling and display in X-ray mammography and tomosynthesis
US7616801B2 (en) 2002-11-27 2009-11-10 Hologic, Inc. Image handling and display in x-ray mammography and tomosynthesis
US8565372B2 (en) 2003-11-26 2013-10-22 Hologic, Inc System and method for low dose tomosynthesis
US7123684B2 (en) 2002-11-27 2006-10-17 Hologic, Inc. Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing
US8768026B2 (en) 2003-11-26 2014-07-01 Hologic, Inc. X-ray imaging with x-ray markers that provide adjunct information but preserve image quality
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
WO2006055830A2 (en) 2004-11-15 2006-05-26 Hologic, Inc. Matching geometry generation and display of mammograms and tomosynthesis images
EP3106094B1 (en) 2004-11-26 2021-09-08 Hologic, Inc. Integrated multi-mode mammography/tomosynthesis x-ray system
US7245694B2 (en) * 2005-08-15 2007-07-17 Hologic, Inc. X-ray mammography/tomosynthesis of patient's breast
WO2013078476A1 (en) 2011-11-27 2013-05-30 Hologic, Inc. System and method for generating a 2d image using mammography and/or tomosynthesis image data
US7465268B2 (en) 2005-11-18 2008-12-16 Senorx, Inc. Methods for asymmetrical irradiation of a body cavity
EP1986548B1 (en) 2006-02-15 2013-01-02 Hologic, Inc. Breast biopsy and needle localization using tomosynthesis systems
US7630533B2 (en) 2007-09-20 2009-12-08 Hologic, Inc. Breast tomosynthesis with display of highlighted suspected calcifications
US7991106B2 (en) 2008-08-29 2011-08-02 Hologic, Inc. Multi-mode tomosynthesis/mammography gain calibration and image correction using gain map information from selected projection angles
KR20110063659A (ko) 2008-09-04 2011-06-13 홀로직, 인크. 통합된 다중 모드 마모그래피/토모신테시스 x선 시스템 및 방법
US9248311B2 (en) 2009-02-11 2016-02-02 Hologic, Inc. System and method for modifying a flexibility of a brachythereapy catheter
US9579524B2 (en) 2009-02-11 2017-02-28 Hologic, Inc. Flexible multi-lumen brachytherapy device
US8170320B2 (en) 2009-03-03 2012-05-01 Hologic, Inc. Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly
US10207126B2 (en) 2009-05-11 2019-02-19 Cytyc Corporation Lumen visualization and identification system for multi-lumen balloon catheter
WO2011043838A1 (en) 2009-10-08 2011-04-14 Hologic, Inc . Needle breast biopsy system and method of use
US9352172B2 (en) 2010-09-30 2016-05-31 Hologic, Inc. Using a guide member to facilitate brachytherapy device swap
CA2813591C (en) 2010-10-05 2020-09-22 Hologic, Inc. Upright x-ray breast imaging with a ct mode, multiple tomosynthesis modes, and a mammography mode
US9075903B2 (en) 2010-11-26 2015-07-07 Hologic, Inc. User interface for medical image review workstation
US10342992B2 (en) 2011-01-06 2019-07-09 Hologic, Inc. Orienting a brachytherapy applicator
JP6057922B2 (ja) 2011-03-08 2017-01-11 ホロジック, インコーポレイテッドHologic, Inc. スクリーニング、診断及び生検のための二重エネルギー及び/又は造影強化乳房撮像のためのシステム及び方法
WO2013123091A1 (en) 2012-02-13 2013-08-22 Hologic, Inc. System and method for navigating a tomosynthesis stack using synthesized image data
JP6388347B2 (ja) 2013-03-15 2018-09-12 ホロジック, インコーポレイテッドHologic, Inc. 腹臥位におけるトモシンセシス誘導生検
EP3964132B1 (en) 2013-10-09 2023-07-19 Hologic, Inc. X-ray breast tomosynthesis enhancing spatial resolution including in the thickness direction of a flattened breast
US11364005B2 (en) 2013-10-24 2022-06-21 Hologic, Inc. System and method for navigating x-ray guided breast biopsy
CN106061389B (zh) 2014-02-28 2019-11-12 霍罗吉克公司 用于生成和显示断层合成图像板块的系统和方法
US10603002B2 (en) 2014-11-07 2020-03-31 Hologic, Inc. Pivoting paddle apparatus for mammography/tomosynthesis X-ray system
EP3445247B1 (en) 2016-04-22 2021-03-10 Hologic, Inc. Tomosynthesis with shifting focal spot x-ray system using an addressable array
US10888292B2 (en) 2016-11-08 2021-01-12 Hologic, Inc. Imaging with curved compression elements
JP7277053B2 (ja) 2017-03-30 2023-05-18 ホロジック, インコーポレイテッド 階層式マルチレベル特徴画像合成および提示のためのシステムおよび方法
WO2018183549A1 (en) 2017-03-30 2018-10-04 Hologic, Inc. System and method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement
EP3600052A1 (en) 2017-03-30 2020-02-05 Hologic, Inc. System and method for targeted object enhancement to generate synthetic breast tissue images
EP3641635A4 (en) 2017-06-20 2021-04-07 Hologic, Inc. DYNAMIC SELF-LEARNING MEDICAL IMAGING PROCESS AND SYSTEM
JP7229228B2 (ja) 2017-08-11 2023-02-27 ホロジック, インコーポレイテッド アクセス角を伴う乳房圧迫パドル
CN111031920B (zh) 2017-08-11 2024-05-07 豪洛捷公司 具有可膨胀护套的乳房压缩桨板
WO2019035064A1 (en) 2017-08-16 2019-02-21 Hologic, Inc. PATIENT MOVEMENT ARTIFACT COMPENSATION TECHNIQUES IN BREAST IMAGING
EP3449835B1 (en) 2017-08-22 2023-01-11 Hologic, Inc. Computed tomography system and method for imaging multiple anatomical targets
US11090017B2 (en) 2018-09-13 2021-08-17 Hologic, Inc. Generating synthesized projection images for 3D breast tomosynthesis or multi-mode x-ray breast imaging
EP3832689A3 (en) 2019-12-05 2021-08-11 Hologic, Inc. Systems and methods for improved x-ray tube life
US11622736B2 (en) 2020-01-24 2023-04-11 Hologic, Inc. Horizontally-displaceable foam breast compression paddle
US11471118B2 (en) 2020-03-27 2022-10-18 Hologic, Inc. System and method for tracking x-ray tube focal spot position
US11786191B2 (en) 2021-05-17 2023-10-17 Hologic, Inc. Contrast-enhanced tomosynthesis with a copper filter

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3609167A (en) * 1962-04-02 1971-09-28 Smith Kline French Lab IBENZO{8 b,e{9 {0 THIEPINES
NL125253C (id) * 1963-12-05
NL152845B (nl) * 1966-03-11 1977-04-15 Boehringer Mannheim Gmbh Werkwijze voor het bereiden van een geneesmiddel met een psychotrope en bloedsomloopstimulerende werking, alsmede het aldus verkregen gevormde geneesmiddel, en werkwijze voor het bereiden van een geneeskrachtig omega,omega-difenylalkylaminederivaat.
FR1518226A (fr) * 1966-04-09 1968-03-22 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide
US4463001A (en) * 1980-10-20 1984-07-31 Farmitalia Carlo Erba S.P.A. 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation

Also Published As

Publication number Publication date
ZA826252B (en) 1983-07-27
US4496557A (en) 1985-01-29
CA1227481A (fr) 1987-09-29
EP0074304B1 (fr) 1985-04-03
ATE12497T1 (de) 1985-04-15
ES8400422A1 (es) 1983-11-01
EP0074304A1 (fr) 1983-03-16
GR77595B (id) 1984-09-25
FR2512024B1 (id) 1984-01-06
JPS5874673A (ja) 1983-05-06
NZ201740A (en) 1985-05-31
PT75471A (fr) 1982-09-01
FR2512024A1 (fr) 1983-03-04
DE3262880D1 (en) 1985-05-09
JPS6129950B2 (id) 1986-07-10
ES515232A0 (es) 1983-11-01
AU8773082A (en) 1983-03-03
PT75471B (fr) 1984-11-19
IL66650A0 (en) 1982-12-31

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