IL65292A - Preparation of 1alpha-hydroxy-5,6-trans-vitamin d compounds - Google Patents
Preparation of 1alpha-hydroxy-5,6-trans-vitamin d compoundsInfo
- Publication number
- IL65292A IL65292A IL65292A IL6529282A IL65292A IL 65292 A IL65292 A IL 65292A IL 65292 A IL65292 A IL 65292A IL 6529282 A IL6529282 A IL 6529282A IL 65292 A IL65292 A IL 65292A
- Authority
- IL
- Israel
- Prior art keywords
- 1alpha
- vitamin
- trans
- hydroxy
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/258,125 US4338250A (en) | 1981-04-27 | 1981-04-27 | 1-Hydroxylation process |
Publications (2)
Publication Number | Publication Date |
---|---|
IL65292A0 IL65292A0 (en) | 1982-05-31 |
IL65292A true IL65292A (en) | 1985-05-31 |
Family
ID=22979185
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL65292A IL65292A (en) | 1981-04-27 | 1982-03-19 | Preparation of 1alpha-hydroxy-5,6-trans-vitamin d compounds |
Country Status (4)
Country | Link |
---|---|
US (1) | US4338250A (xx) |
EP (1) | EP0077353A1 (xx) |
IL (1) | IL65292A (xx) |
WO (1) | WO1982003864A1 (xx) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0078705B1 (en) * | 1981-11-02 | 1988-04-27 | Research Institute For Medicine And Chemistry Inc. | Process for the preparation of 1-hydroxylated vitamin d compounds |
US4508651A (en) * | 1983-03-21 | 1985-04-02 | Hoffmann-La Roche Inc. | Synthesis of 1α,25-dihydroxyergocalciferol |
US4551214A (en) * | 1983-07-01 | 1985-11-05 | Hoffmann-La Roche Inc. | Photochemical preparation of previtamin D |
JPS6089422A (ja) * | 1983-10-24 | 1985-05-20 | Kureha Chem Ind Co Ltd | 抗骨粗鬆症剤 |
US4769181A (en) * | 1983-11-07 | 1988-09-06 | Wisconsin Alumni Research Foundation | 1,25-dihydroxyvitamin D2 compounds |
US4554106A (en) * | 1984-11-01 | 1985-11-19 | Wisconsin Alumni Research Foundation | Method for preparing 1α-hydroxyvitamin D compounds |
EP0184112B1 (en) * | 1984-11-27 | 1990-05-09 | Chugai Seiyaku Kabushiki Kaisha | Novel vitamin d derivatives and process for producing the same |
US5001118A (en) * | 1986-12-29 | 1991-03-19 | Kureha Kagaku Kogyo Kabushiki Kaisha | Method for preventing senescence and increasing bone mass |
US4892821A (en) * | 1987-07-08 | 1990-01-09 | Taisho Pharmaceutical Co., Ltd. | Method for preparing vitamin D compounds |
JP2645130B2 (ja) * | 1989-03-31 | 1997-08-25 | 日清製粉株式会社 | ステロイド誘導体 |
US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
US5185150A (en) * | 1990-08-24 | 1993-02-09 | Wisconsin Alumni Research Fdn. | Cosmetic compositions containing 19-nor-vitamin D compounds |
US5756783A (en) * | 1990-09-21 | 1998-05-26 | Bone Care International, Inc. | 1α-Hydroxy-24-EPI-vitamin D4 |
US20040009958A1 (en) * | 1991-01-08 | 2004-01-15 | Bone Care International, Inc. | Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2 |
US6538037B2 (en) | 1991-01-08 | 2003-03-25 | Bone Care International, Inc. | Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2 |
US6166000A (en) * | 1991-01-08 | 2000-12-26 | Bone Care International, Inc. | Methods for preparation and use of 1α,24(S)-Dihydroxy vitamin . D.sub2 |
US6251883B1 (en) | 1991-01-08 | 2001-06-26 | Bone Care International, Inc. | Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2 |
US5786348A (en) * | 1991-01-08 | 1998-07-28 | Bone Care International, Inc. | Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2 |
DE69233074T2 (de) * | 1991-01-08 | 2004-03-18 | Bone Care International Inc., Madison | Verfahren zur Herstellung von 1-alpha-24-dihydroxy-Vitamin D2 |
US5225569A (en) * | 1991-08-09 | 1993-07-06 | Hoffmann-La Roche Inc. | Process for precursors to calcitriol and related compounds |
US5182393A (en) * | 1991-08-09 | 1993-01-26 | Hoffmann-La Roche Inc. | Process for precursors to calcitriol and related compounds |
WO1993014763A1 (en) * | 1992-01-29 | 1993-08-05 | Lunar Corporation | 1α-HYDROXY-24-EPI-VITAMIN D¿4? |
AU4841193A (en) * | 1992-08-28 | 1994-03-29 | Lunar Corporation | 1alpha,24(S)-dihydroxy vitamin D2, its formation and use |
US5565589A (en) * | 1993-11-03 | 1996-10-15 | Wisconsin Alumni Research Foundation | 17-formyl-5,6-trans-vitamin D compounds |
US5869472A (en) * | 1994-07-18 | 1999-02-09 | Bone Care International, Inc. | Synthesis of 1α-hydroxy vitamin D |
US6432936B1 (en) | 1999-01-20 | 2002-08-13 | Wisconsin Alumni Research Foundation | Crystalline 1α-hydroxyvitamin D2 and method of purification thereof |
US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
CN1948283B (zh) * | 2005-10-14 | 2010-12-29 | 台耀化学股份有限公司 | 维生素d衍生物的制备方法 |
US20120184514A1 (en) * | 2009-07-01 | 2012-07-19 | Vitamin Derivatives Inc. | Vitamin d compounds and methods for preparing same |
CN103073468A (zh) * | 2012-11-27 | 2013-05-01 | 天津大学 | 一种骨质疏松治疗药1α-羟基维生素D3的合成方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3847955A (en) * | 1973-07-16 | 1974-11-12 | Wisconsin Alumni Res Found | 1,24,25-trihydroxycholecalciferol |
US4022891A (en) * | 1974-06-18 | 1977-05-10 | Teijin Limited | Novel 1α,24-dihydroxycholecalciferol compositions, novel precursors thereof, and processes for preparing them |
US4202829A (en) * | 1978-01-05 | 1980-05-13 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
US4206131A (en) * | 1978-06-19 | 1980-06-03 | The Upjohn Company | Compounds and process |
PH16989A (en) * | 1978-11-07 | 1984-05-04 | Res Inst Medicine Chem | Process for the preparation of 1-hydroxylated vitamin d compounds |
LU80545A1 (de) * | 1978-11-17 | 1980-06-05 | Hoffmann La Roche | Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden |
US4265822A (en) * | 1979-09-10 | 1981-05-05 | Wisconsin Alumni Research Foundation | Process for preparing 1-hydroxylated vitamin D compounds from 5,6-trans-vitamin D compounds |
US4305880A (en) * | 1980-09-22 | 1981-12-15 | Wisconsin Alumni Research Foundation | Process for preparing 24-fluoro-25-hydroxycholecalciferol |
-
1981
- 1981-04-27 US US06/258,125 patent/US4338250A/en not_active Expired - Lifetime
-
1982
- 1982-03-15 EP EP82901246A patent/EP0077353A1/en not_active Withdrawn
- 1982-03-15 WO PCT/US1982/000325 patent/WO1982003864A1/en unknown
- 1982-03-19 IL IL65292A patent/IL65292A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1982003864A1 (en) | 1982-11-11 |
IL65292A0 (en) | 1982-05-31 |
EP0077353A1 (en) | 1983-04-27 |
US4338250A (en) | 1982-07-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |