IL65232A - Beta-lactam acetic acid derivatives,process for preparing them and their use as intermediates for 1-azabicyclo(3.2.0)-hept-2-ene antibiotics - Google Patents
Beta-lactam acetic acid derivatives,process for preparing them and their use as intermediates for 1-azabicyclo(3.2.0)-hept-2-ene antibioticsInfo
- Publication number
- IL65232A IL65232A IL65232A IL6523282A IL65232A IL 65232 A IL65232 A IL 65232A IL 65232 A IL65232 A IL 65232A IL 6523282 A IL6523282 A IL 6523282A IL 65232 A IL65232 A IL 65232A
- Authority
- IL
- Israel
- Prior art keywords
- preparing
- acetic acid
- acid derivatives
- beta
- azabicyclo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8107865 | 1981-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL65232A0 IL65232A0 (en) | 1982-05-31 |
| IL65232A true IL65232A (en) | 1986-01-31 |
Family
ID=10520350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL65232A IL65232A (en) | 1981-03-12 | 1982-03-12 | Beta-lactam acetic acid derivatives,process for preparing them and their use as intermediates for 1-azabicyclo(3.2.0)-hept-2-ene antibiotics |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4576746A (xx) |
| EP (1) | EP0060416B1 (xx) |
| JP (1) | JPS57159761A (xx) |
| KR (1) | KR880001847B1 (xx) |
| AT (1) | ATE21509T1 (xx) |
| AU (1) | AU548727B2 (xx) |
| CA (1) | CA1185244A (xx) |
| DE (1) | DE3272660D1 (xx) |
| DK (1) | DK103982A (xx) |
| ES (2) | ES8308540A1 (xx) |
| IE (1) | IE52609B1 (xx) |
| IL (1) | IL65232A (xx) |
| PH (1) | PH23415A (xx) |
| ZA (1) | ZA821252B (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU187424B (en) * | 1982-11-05 | 1986-01-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing new azetidinyl-acetic acids |
| JPS60224672A (ja) * | 1984-04-23 | 1985-11-09 | Sumitomo Chem Co Ltd | β−ラクタム誘導体の製造法 |
| JPS62209079A (ja) * | 1986-03-11 | 1987-09-14 | Sanraku Inc | 二置換アミノカルバペナム類 |
| JP2618271B2 (ja) * | 1989-04-26 | 1997-06-11 | 日本化薬株式会社 | モノｐ―ニトロベンジルマロネートマグネシウム塩の結晶変態及びその製法 |
| UA50705C2 (uk) * | 1992-09-18 | 2002-11-15 | Мерк Енд Ко, Інк | СПОСОБИ ОДЕРЖАННЯ ПРОМІЖНИХ СПОЛУК <font face="Symbol">b</font>-МЕТИЛКАРБАПЕНЕМУ, ПРОМІЖНІ CПОЛУКИ |
| US5516934A (en) * | 1994-08-05 | 1996-05-14 | Nippon Kayaku Kabushiki Kaisha | Process for producing mono-P-nitrobenzyl malonate |
| US20040148868A1 (en) * | 2003-02-05 | 2004-08-05 | 3M Innovative Properties Company | Methods of making ceramics |
| CN101098970B (zh) * | 2004-12-10 | 2010-05-12 | V.B.医疗保险私人有限公司 | 通过在6-乙酰基-4,1',6'三氯半乳蔗糖和4,1',6'三氯半乳蔗糖的有机溶剂提取物的浓缩过程中直接加入碳酸盐和碳酸氢盐来调节pH的方法 |
| ES2670576T3 (es) | 2009-09-03 | 2018-05-31 | Pfizer Vaccines Llc | Vacuna de PCSK9 |
| WO2011048583A1 (en) * | 2009-10-23 | 2011-04-28 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
| CN103483202B (zh) * | 2013-06-26 | 2015-01-21 | 华北水利水电大学 | 一种对硝基苄醇丙二酸单酯镁的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1570278A (en) * | 1975-10-06 | 1980-06-25 | Fujisawa Pharmaceutical Co | O-substituted-2-azetidinone derivatives and the preparation thereof |
| US4138400A (en) * | 1975-12-20 | 1979-02-06 | Hoechst Aktiengesellschaft | Omega-alkoxy derivatives of lactams |
| GB1584762A (en) * | 1977-04-01 | 1981-02-18 | Beecham Group Ltd | Azabicycloheptenes |
| EP0017992A1 (en) * | 1979-04-19 | 1980-10-29 | Merck & Co. Inc. | 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates |
| US4290947A (en) * | 1979-04-27 | 1981-09-22 | Merck & Co., Inc. | Process for the preparation of thienamycin and intermediates |
| US4262010A (en) * | 1979-12-03 | 1981-04-14 | Merck & Co., Inc. | 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4312871A (en) * | 1979-12-03 | 1982-01-26 | Merck & Co., Inc. | 6-, 1- And 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4287123A (en) * | 1980-01-14 | 1981-09-01 | Merck & Co., Inc. | Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate |
| US4282148A (en) * | 1980-01-14 | 1981-08-04 | Merck & Co., Inc. | Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid |
| US4269772A (en) * | 1980-01-14 | 1981-05-26 | Merck & Co., Inc. | Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline |
-
1982
- 1982-02-24 AU AU80765/82A patent/AU548727B2/en not_active Ceased
- 1982-02-25 ZA ZA821252A patent/ZA821252B/xx unknown
- 1982-02-26 AT AT82101463T patent/ATE21509T1/de not_active IP Right Cessation
- 1982-02-26 EP EP82101463A patent/EP0060416B1/en not_active Expired
- 1982-02-26 DE DE8282101463T patent/DE3272660D1/de not_active Expired
- 1982-03-04 PH PH26950A patent/PH23415A/en unknown
- 1982-03-04 US US06/354,572 patent/US4576746A/en not_active Expired - Fee Related
- 1982-03-10 DK DK103982A patent/DK103982A/da not_active Application Discontinuation
- 1982-03-11 ES ES510336A patent/ES8308540A1/es not_active Expired
- 1982-03-11 KR KR8201103A patent/KR880001847B1/ko active
- 1982-03-11 CA CA000398140A patent/CA1185244A/en not_active Expired
- 1982-03-11 IE IE554/82A patent/IE52609B1/en unknown
- 1982-03-12 JP JP57039284A patent/JPS57159761A/ja active Pending
- 1982-03-12 IL IL65232A patent/IL65232A/xx unknown
- 1982-10-25 ES ES516808A patent/ES516808A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IL65232A0 (en) | 1982-05-31 |
| DE3272660D1 (en) | 1986-09-25 |
| EP0060416A1 (en) | 1982-09-22 |
| JPS57159761A (en) | 1982-10-01 |
| EP0060416B1 (en) | 1986-08-20 |
| AU8076582A (en) | 1982-09-16 |
| ZA821252B (en) | 1983-01-26 |
| AU548727B2 (en) | 1986-01-02 |
| KR830009020A (ko) | 1983-12-17 |
| PH23415A (en) | 1989-08-07 |
| CA1185244A (en) | 1985-04-09 |
| IE52609B1 (en) | 1987-12-23 |
| ES8402590A1 (es) | 1984-02-01 |
| IE820554L (en) | 1982-09-12 |
| ES510336A0 (es) | 1983-09-01 |
| ATE21509T1 (de) | 1986-09-15 |
| KR880001847B1 (ko) | 1988-09-22 |
| US4576746A (en) | 1986-03-18 |
| ES516808A0 (es) | 1984-02-01 |
| ES8308540A1 (es) | 1983-09-01 |
| DK103982A (da) | 1982-09-13 |
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