IL65232A - Beta-lactam acetic acid derivatives,process for preparing them and their use as intermediates for 1-azabicyclo(3.2.0)-hept-2-ene antibiotics - Google Patents
Beta-lactam acetic acid derivatives,process for preparing them and their use as intermediates for 1-azabicyclo(3.2.0)-hept-2-ene antibioticsInfo
- Publication number
- IL65232A IL65232A IL65232A IL6523282A IL65232A IL 65232 A IL65232 A IL 65232A IL 65232 A IL65232 A IL 65232A IL 6523282 A IL6523282 A IL 6523282A IL 65232 A IL65232 A IL 65232A
- Authority
- IL
- Israel
- Prior art keywords
- preparing
- acetic acid
- acid derivatives
- beta
- azabicyclo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8107865 | 1981-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL65232A0 IL65232A0 (en) | 1982-05-31 |
| IL65232A true IL65232A (en) | 1986-01-31 |
Family
ID=10520350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL65232A IL65232A (en) | 1981-03-12 | 1982-03-12 | Beta-lactam acetic acid derivatives,process for preparing them and their use as intermediates for 1-azabicyclo(3.2.0)-hept-2-ene antibiotics |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4576746A (xx) |
| EP (1) | EP0060416B1 (xx) |
| JP (1) | JPS57159761A (xx) |
| KR (1) | KR880001847B1 (xx) |
| AT (1) | ATE21509T1 (xx) |
| AU (1) | AU548727B2 (xx) |
| CA (1) | CA1185244A (xx) |
| DE (1) | DE3272660D1 (xx) |
| DK (1) | DK103982A (xx) |
| ES (2) | ES8308540A1 (xx) |
| IE (1) | IE52609B1 (xx) |
| IL (1) | IL65232A (xx) |
| PH (1) | PH23415A (xx) |
| ZA (1) | ZA821252B (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU187424B (en) * | 1982-11-05 | 1986-01-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing new azetidinyl-acetic acids |
| JPS60224672A (ja) * | 1984-04-23 | 1985-11-09 | Sumitomo Chem Co Ltd | β−ラクタム誘導体の製造法 |
| JPS62209079A (ja) * | 1986-03-11 | 1987-09-14 | Sanraku Inc | 二置換アミノカルバペナム類 |
| JP2618271B2 (ja) * | 1989-04-26 | 1997-06-11 | 日本化薬株式会社 | モノｐ―ニトロベンジルマロネートマグネシウム塩の結晶変態及びその製法 |
| CZ286267B6 (cs) * | 1992-09-18 | 2000-03-15 | Merck & Co., Inc | Způsob výroby karbapenemových meziproduktů a meziprodukty pro povádění tohoto postupu |
| US5516934A (en) * | 1994-08-05 | 1996-05-14 | Nippon Kayaku Kabushiki Kaisha | Process for producing mono-P-nitrobenzyl malonate |
| US20040148868A1 (en) * | 2003-02-05 | 2004-08-05 | 3M Innovative Properties Company | Methods of making ceramics |
| WO2006061854A2 (en) * | 2004-12-10 | 2006-06-15 | Pharmed Medicare Private Limited | CONTROL OF pH BY DIRECT ADDITION OF CARBONATES AND BICARBONATES DURING CONCENTRATION OF ORGANIC SOLVENT EXTRACTS OF 6- ACETYL- 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE AND 4,1 ‘, 6' TRICHLOROGALACTOSUCROSE |
| PT2473605T (pt) | 2009-09-03 | 2018-05-28 | Pfizer Vaccines Llc | Vacina pcsk9 |
| WO2011048583A1 (en) * | 2009-10-23 | 2011-04-28 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
| CN103483202B (zh) * | 2013-06-26 | 2015-01-21 | 华北水利水电大学 | 一种对硝基苄醇丙二酸单酯镁的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1570278A (en) * | 1975-10-06 | 1980-06-25 | Fujisawa Pharmaceutical Co | O-substituted-2-azetidinone derivatives and the preparation thereof |
| US4138400A (en) * | 1975-12-20 | 1979-02-06 | Hoechst Aktiengesellschaft | Omega-alkoxy derivatives of lactams |
| GB1584762A (en) * | 1977-04-01 | 1981-02-18 | Beecham Group Ltd | Azabicycloheptenes |
| EP0017992A1 (en) * | 1979-04-19 | 1980-10-29 | Merck & Co. Inc. | 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates |
| US4290947A (en) * | 1979-04-27 | 1981-09-22 | Merck & Co., Inc. | Process for the preparation of thienamycin and intermediates |
| US4312871A (en) * | 1979-12-03 | 1982-01-26 | Merck & Co., Inc. | 6-, 1- And 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4262010A (en) * | 1979-12-03 | 1981-04-14 | Merck & Co., Inc. | 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4269772A (en) * | 1980-01-14 | 1981-05-26 | Merck & Co., Inc. | Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline |
| US4287123A (en) * | 1980-01-14 | 1981-09-01 | Merck & Co., Inc. | Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate |
| US4282148A (en) * | 1980-01-14 | 1981-08-04 | Merck & Co., Inc. | Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid |
-
1982
- 1982-02-24 AU AU80765/82A patent/AU548727B2/en not_active Ceased
- 1982-02-25 ZA ZA821252A patent/ZA821252B/xx unknown
- 1982-02-26 AT AT82101463T patent/ATE21509T1/de not_active IP Right Cessation
- 1982-02-26 EP EP82101463A patent/EP0060416B1/en not_active Expired
- 1982-02-26 DE DE8282101463T patent/DE3272660D1/de not_active Expired
- 1982-03-04 PH PH26950A patent/PH23415A/en unknown
- 1982-03-04 US US06/354,572 patent/US4576746A/en not_active Expired - Fee Related
- 1982-03-10 DK DK103982A patent/DK103982A/da not_active Application Discontinuation
- 1982-03-11 KR KR8201103A patent/KR880001847B1/ko active
- 1982-03-11 CA CA000398140A patent/CA1185244A/en not_active Expired
- 1982-03-11 IE IE554/82A patent/IE52609B1/en unknown
- 1982-03-11 ES ES510336A patent/ES8308540A1/es not_active Expired
- 1982-03-12 JP JP57039284A patent/JPS57159761A/ja active Pending
- 1982-03-12 IL IL65232A patent/IL65232A/xx unknown
- 1982-10-25 ES ES516808A patent/ES8402590A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4576746A (en) | 1986-03-18 |
| ATE21509T1 (de) | 1986-09-15 |
| AU548727B2 (en) | 1986-01-02 |
| DK103982A (da) | 1982-09-13 |
| ES516808A0 (es) | 1984-02-01 |
| EP0060416B1 (en) | 1986-08-20 |
| ES8402590A1 (es) | 1984-02-01 |
| CA1185244A (en) | 1985-04-09 |
| KR880001847B1 (ko) | 1988-09-22 |
| EP0060416A1 (en) | 1982-09-22 |
| DE3272660D1 (en) | 1986-09-25 |
| ZA821252B (en) | 1983-01-26 |
| IE820554L (en) | 1982-09-12 |
| JPS57159761A (en) | 1982-10-01 |
| PH23415A (en) | 1989-08-07 |
| IE52609B1 (en) | 1987-12-23 |
| ES510336A0 (es) | 1983-09-01 |
| IL65232A0 (en) | 1982-05-31 |
| KR830009020A (ko) | 1983-12-17 |
| ES8308540A1 (es) | 1983-09-01 |
| AU8076582A (en) | 1982-09-16 |
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