IL63782A - 2-(1,4-benzodioxan-2-ylalkyl)imidazoles,their preparation and pharmaceutical compositions containing them - Google Patents
2-(1,4-benzodioxan-2-ylalkyl)imidazoles,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL63782A IL63782A IL63782A IL6378281A IL63782A IL 63782 A IL63782 A IL 63782A IL 63782 A IL63782 A IL 63782A IL 6378281 A IL6378281 A IL 6378281A IL 63782 A IL63782 A IL 63782A
- Authority
- IL
- Israel
- Prior art keywords
- ylalkyl
- benzodioxan
- imidazoles
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/185,832 US4302469A (en) | 1980-09-10 | 1980-09-10 | 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antidepressants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL63782A0 IL63782A0 (en) | 1981-12-31 |
| IL63782A true IL63782A (en) | 1984-03-30 |
Family
ID=22682624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL63782A IL63782A (en) | 1980-09-10 | 1981-09-09 | 2-(1,4-benzodioxan-2-ylalkyl)imidazoles,their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4302469A (da) |
| EP (1) | EP0047531B1 (da) |
| JP (1) | JPS5750989A (da) |
| KR (1) | KR830007626A (da) |
| AT (1) | ATE13765T1 (da) |
| AU (1) | AU541413B2 (da) |
| CA (1) | CA1173044A (da) |
| DE (1) | DE3170937D1 (da) |
| DK (1) | DK400781A (da) |
| ES (1) | ES505329A0 (da) |
| FI (1) | FI812804A7 (da) |
| HU (1) | HU186781B (da) |
| IL (1) | IL63782A (da) |
| NO (1) | NO813065L (da) |
| NZ (1) | NZ198321A (da) |
| YU (1) | YU217181A (da) |
| ZA (1) | ZA816259B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH16249A (en) * | 1980-02-04 | 1983-08-16 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives,its pharmaceutical composition and method of use |
| US4402967A (en) * | 1981-04-23 | 1983-09-06 | Syntex (U.S.A.) Inc. | Method for lowering intraocular pressure |
| US4436914A (en) * | 1981-08-03 | 1984-03-13 | Kluge Arthur F | Benzodioxane-imidazoline compounds as antihypertensives |
| US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
| FI833224A7 (fi) * | 1983-09-09 | 1985-03-10 | Farmos Oy | Menetelmä terapeuttisesti tehokkaan aineen valmistamiseksi. |
| US4634714A (en) * | 1983-12-01 | 1987-01-06 | American Home Products Corporation | Inhibition of prolactin release by a benzodioxinylimidazoline derivative |
| GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
| US4943311A (en) * | 1988-05-09 | 1990-07-24 | Uniroyal Chemical Company, Inc. | Azole derivatives of spiroheterocycles |
| IL95760A0 (en) * | 1989-09-27 | 1992-05-25 | Rhone Poulenc Sante | Imidazole derivatives,their preparation and pharmaceutical compositions containing the same |
| GB9020889D0 (en) * | 1990-09-25 | 1990-11-07 | May & Baker Ltd | New compositions of matter |
| US6162455A (en) * | 1997-01-22 | 2000-12-19 | American Cyanamid Company | Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals |
| US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| WO2005037260A2 (en) * | 2003-10-14 | 2005-04-28 | Wyeth | Use of adrenergic alphaze antagonists for the treatment of vasomotor symptoms |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA731147A (en) | 1966-03-29 | Charles E. Frosst And Co. | 1:4 benzodioxan derivatives | |
| US2979511A (en) * | 1959-03-25 | 1961-04-11 | Olin Mathieson | Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process |
| US3360529A (en) * | 1962-01-29 | 1967-12-26 | Smith Kline French Lab | Guanidinoalkylbenzodioxan derivatives |
| GB1094982A (en) | 1963-05-08 | 1967-12-13 | Ward Blenkinsop & Co Ltd | 1,4-benzodioxanes |
| BE643853A (da) | 1964-02-20 | 1964-08-14 | ||
| US3829411A (en) * | 1972-03-29 | 1974-08-13 | Eastman Kodak Co | Thiadiazolyl-azo-indole compounds |
| GB1411531A (en) * | 1972-10-24 | 1975-10-29 | Lafon Labor | Amino derivatives of 1,4-benzodioxan |
| GB1457038A (en) * | 1973-10-23 | 1976-12-01 | Lafon Labor | Amino derivatives of 1,4-benzodioxan |
| GB1520801A (en) | 1975-01-16 | 1978-08-09 | Lafon Labor | Benzodioxanyl and benzofuranylmethylamines |
| US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
-
1980
- 1980-09-10 US US06/185,832 patent/US4302469A/en not_active Expired - Lifetime
-
1981
- 1981-05-25 JP JP56079118A patent/JPS5750989A/ja active Pending
- 1981-09-09 NZ NZ198321A patent/NZ198321A/en unknown
- 1981-09-09 NO NO813065A patent/NO813065L/no unknown
- 1981-09-09 EP EP81107104A patent/EP0047531B1/en not_active Expired
- 1981-09-09 HU HU812591A patent/HU186781B/hu unknown
- 1981-09-09 CA CA000385505A patent/CA1173044A/en not_active Expired
- 1981-09-09 KR KR1019810003367A patent/KR830007626A/ko not_active Withdrawn
- 1981-09-09 DE DE8181107104T patent/DE3170937D1/de not_active Expired
- 1981-09-09 DK DK400781A patent/DK400781A/da not_active Application Discontinuation
- 1981-09-09 AT AT81107104T patent/ATE13765T1/de not_active IP Right Cessation
- 1981-09-09 FI FI812804A patent/FI812804A7/fi not_active Application Discontinuation
- 1981-09-09 ZA ZA816259A patent/ZA816259B/xx unknown
- 1981-09-09 IL IL63782A patent/IL63782A/xx unknown
- 1981-09-09 ES ES505329A patent/ES505329A0/es active Granted
- 1981-09-09 AU AU75094/81A patent/AU541413B2/en not_active Ceased
- 1981-09-09 YU YU02171/81A patent/YU217181A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO813065L (no) | 1982-03-11 |
| CA1173044A (en) | 1984-08-21 |
| US4302469A (en) | 1981-11-24 |
| ZA816259B (en) | 1983-04-27 |
| YU217181A (en) | 1983-10-31 |
| ATE13765T1 (de) | 1985-06-15 |
| AU7509481A (en) | 1982-03-18 |
| JPS5750989A (en) | 1982-03-25 |
| FI812804L (fi) | 1982-03-11 |
| KR830007626A (ko) | 1983-11-04 |
| IL63782A0 (en) | 1981-12-31 |
| EP0047531A1 (en) | 1982-03-17 |
| NZ198321A (en) | 1985-07-12 |
| AU541413B2 (en) | 1985-01-10 |
| FI812804A7 (fi) | 1982-03-11 |
| ES8205791A1 (es) | 1982-08-16 |
| EP0047531B1 (en) | 1985-06-12 |
| ES505329A0 (es) | 1982-08-16 |
| DK400781A (da) | 1982-03-11 |
| DE3170937D1 (en) | 1985-07-18 |
| HU186781B (en) | 1985-09-30 |
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