DE3170937D1 - 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them - Google Patents
2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- DE3170937D1 DE3170937D1 DE8181107104T DE3170937T DE3170937D1 DE 3170937 D1 DE3170937 D1 DE 3170937D1 DE 8181107104 T DE8181107104 T DE 8181107104T DE 3170937 T DE3170937 T DE 3170937T DE 3170937 D1 DE3170937 D1 DE 3170937D1
- Authority
- DE
- Germany
- Prior art keywords
- ylalkyl
- benzodioxan
- imidazoles
- preparation
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/185,832 US4302469A (en) | 1980-09-10 | 1980-09-10 | 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antidepressants |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3170937D1 true DE3170937D1 (en) | 1985-07-18 |
Family
ID=22682624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8181107104T Expired DE3170937D1 (en) | 1980-09-10 | 1981-09-09 | 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them |
Country Status (17)
Country | Link |
---|---|
US (1) | US4302469A (de) |
EP (1) | EP0047531B1 (de) |
JP (1) | JPS5750989A (de) |
KR (1) | KR830007626A (de) |
AT (1) | ATE13765T1 (de) |
AU (1) | AU541413B2 (de) |
CA (1) | CA1173044A (de) |
DE (1) | DE3170937D1 (de) |
DK (1) | DK400781A (de) |
ES (1) | ES8205791A1 (de) |
FI (1) | FI812804L (de) |
HU (1) | HU186781B (de) |
IL (1) | IL63782A (de) |
NO (1) | NO813065L (de) |
NZ (1) | NZ198321A (de) |
YU (1) | YU217181A (de) |
ZA (1) | ZA816259B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH16249A (en) * | 1980-02-04 | 1983-08-16 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives,its pharmaceutical composition and method of use |
US4402967A (en) * | 1981-04-23 | 1983-09-06 | Syntex (U.S.A.) Inc. | Method for lowering intraocular pressure |
US4436914A (en) * | 1981-08-03 | 1984-03-13 | Kluge Arthur F | Benzodioxane-imidazoline compounds as antihypertensives |
US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
FI833224A (fi) * | 1983-09-09 | 1985-03-10 | Farmos Oy | Foerfarande foer framstaellning av ett terapeutiskt aktivt aemne. |
US4634714A (en) * | 1983-12-01 | 1987-01-06 | American Home Products Corporation | Inhibition of prolactin release by a benzodioxinylimidazoline derivative |
GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
US4943311A (en) * | 1988-05-09 | 1990-07-24 | Uniroyal Chemical Company, Inc. | Azole derivatives of spiroheterocycles |
IL95760A0 (en) * | 1989-09-27 | 1992-05-25 | Rhone Poulenc Sante | Imidazole derivatives,their preparation and pharmaceutical compositions containing the same |
GB9020889D0 (en) * | 1990-09-25 | 1990-11-07 | May & Baker Ltd | New compositions of matter |
US6162455A (en) * | 1997-01-22 | 2000-12-19 | American Cyanamid Company | Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals |
US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
AU2004281750A1 (en) * | 2003-10-14 | 2005-04-28 | Wyeth | Use of adrenergic alphaze antagonists for the treatment of vasomotor symptoms |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA731147A (en) | 1966-03-29 | Charles E. Frosst And Co. | 1:4 benzodioxan derivatives | |
US2979511A (en) * | 1959-03-25 | 1961-04-11 | Olin Mathieson | Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process |
US3360529A (en) * | 1962-01-29 | 1967-12-26 | Smith Kline French Lab | Guanidinoalkylbenzodioxan derivatives |
GB1094982A (en) | 1963-05-08 | 1967-12-13 | Ward Blenkinsop & Co Ltd | 1,4-benzodioxanes |
BE643853A (de) | 1964-02-20 | 1964-08-14 | ||
US3829411A (en) * | 1972-03-29 | 1974-08-13 | Eastman Kodak Co | Thiadiazolyl-azo-indole compounds |
GB1411531A (en) * | 1972-10-24 | 1975-10-29 | Lafon Labor | Amino derivatives of 1,4-benzodioxan |
GB1457038A (en) * | 1973-10-23 | 1976-12-01 | Lafon Labor | Amino derivatives of 1,4-benzodioxan |
GB1520801A (en) | 1975-01-16 | 1978-08-09 | Lafon Labor | Benzodioxanyl and benzofuranylmethylamines |
US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
-
1980
- 1980-09-10 US US06/185,832 patent/US4302469A/en not_active Expired - Lifetime
-
1981
- 1981-05-25 JP JP56079118A patent/JPS5750989A/ja active Pending
- 1981-09-09 CA CA000385505A patent/CA1173044A/en not_active Expired
- 1981-09-09 DK DK400781A patent/DK400781A/da not_active Application Discontinuation
- 1981-09-09 NZ NZ198321A patent/NZ198321A/en unknown
- 1981-09-09 IL IL63782A patent/IL63782A/xx unknown
- 1981-09-09 FI FI812804A patent/FI812804L/fi not_active Application Discontinuation
- 1981-09-09 EP EP81107104A patent/EP0047531B1/de not_active Expired
- 1981-09-09 YU YU02171/81A patent/YU217181A/xx unknown
- 1981-09-09 DE DE8181107104T patent/DE3170937D1/de not_active Expired
- 1981-09-09 AT AT81107104T patent/ATE13765T1/de not_active IP Right Cessation
- 1981-09-09 HU HU812591A patent/HU186781B/hu unknown
- 1981-09-09 NO NO813065A patent/NO813065L/no unknown
- 1981-09-09 ZA ZA816259A patent/ZA816259B/xx unknown
- 1981-09-09 KR KR1019810003367A patent/KR830007626A/ko unknown
- 1981-09-09 AU AU75094/81A patent/AU541413B2/en not_active Ceased
- 1981-09-09 ES ES505329A patent/ES8205791A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL63782A0 (en) | 1981-12-31 |
ES505329A0 (es) | 1982-08-16 |
FI812804L (fi) | 1982-03-11 |
NZ198321A (en) | 1985-07-12 |
JPS5750989A (en) | 1982-03-25 |
DK400781A (da) | 1982-03-11 |
KR830007626A (ko) | 1983-11-04 |
YU217181A (en) | 1983-10-31 |
ZA816259B (en) | 1983-04-27 |
AU541413B2 (en) | 1985-01-10 |
ATE13765T1 (de) | 1985-06-15 |
AU7509481A (en) | 1982-03-18 |
EP0047531B1 (de) | 1985-06-12 |
HU186781B (en) | 1985-09-30 |
IL63782A (en) | 1984-03-30 |
NO813065L (no) | 1982-03-11 |
US4302469A (en) | 1981-11-24 |
CA1173044A (en) | 1984-08-21 |
ES8205791A1 (es) | 1982-08-16 |
EP0047531A1 (de) | 1982-03-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |